Publications by authors named "Han-Yu Shih"

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Epigenomic Control of Immunity: From Mechanisms to Therapeutic Targets in Inflammatory Bowel Diseases.
Han-Yu Shih, Giuseppe Sciumè, Yohei Mikami

Int Immunol· July 2025

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Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4.
Roxan A Stephenson, Jordy Sepulveda, Kory R Johnson, Adrian Lita, Jaanam Gopalakrishnan, Han-Yu Shih

Cell Rep· July 2025

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Selective requirement of glycosphingolipid synthesis for natural killer and cytotoxic T cells.
Tasha A Morrison, Jaelyn Vigee, Kevin A Tovar, Taylor A Talley, Adriana M Mujal, Han-Yu Shih

Cell· June 2025

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A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification.
Chunhong Liu, Hiroyuki Nagashima, Nilisha Fernando, Victor Bass, Jaanam Gopalakrishnan, Han-Yu Shih

Immunity· May 2024

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Triglyceride metabolism controls inflammation and -associated disease states in microglia.
Roxan A Stephenson, Kory R Johnson, Linling Cheng, Linda G Yang, Jessica T Root, Han-Yu Shih

bioRxiv· April 2024

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Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss.
Nilisha Fernando, Jaanam Gopalakrishnan, Adam Behensky, Lauren Reich, Chunhong Liu, Han-Yu Shih

bioRxiv· March 2023

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When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer.
Mohamed S Hasim, Marie Marotel, Jonathan J Hodgins, Elisabetta Vulpis, Olivia J Makinson, Han-Yu Shih

Sci Adv· April 2022

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Mucus sialylation determines intestinal host-commensal homeostasis.
Yikun Yao, Girak Kim, Samantha Shafer, Zuojia Chen, Satoshi Kubo, Han-Yu Shih

Cell· March 2022

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Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory.
Tasha A Morrison, William H Hudson, Danielle A Chisolm, Yuka Kanno, Han-Yu Shih

Cold Spring Harb Perspect Biol· January 2022

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Stability and change in epigenetic regulation of immune cells.
James Scott-Browne, Han-Yu Shih

Immunol Rev· January 2022

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Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver.
Chiara Di Censo, Marie Marotel, Irene Mattiola, Lena Müller, Gianluca Scarno, Han-Yu Shih

Eur J Immunol· November 2021

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PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8 T cells at the expense of central memory.
Jennifer L Cannons, Alejandro V Villarino, Senta M Kapnick, Silvia Preite, Han-Yu Shih

Cell Rep· October 2021

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Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes.
Nilisha Fernando, Giuseppe Sciumè, John J O'Shea, Han-Yu Shih

Front Immunol· September 2021

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Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring.
Ai Ing Lim, Taryn McFadden, Verena M Link, Seong-Ji Han, Rose-Marie Karlsson, Han-Yu Shih

Science· August 2021

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Neuronal enhancers are hotspots for DNA single-strand break repair.
Wei Wu, Sarah E Kargbo-Hill, William J Nathan, Jacob Paiano, Elsa Callen, Han-Yu Shih

Nature· May 2021

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MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.
Yohei Mikami, Rachael L Philips, Giuseppe Sciumè, Franziska Petermann, Françoise Meylan, Han-Yu Shih

Immunity· March 2021

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Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells.
Giuseppe Sciumè, Yohei Mikami, Dragana Jankovic, Hiroyuki Nagashima, Alejandro V Villarino, Han-Yu Shih

Immunity· October 2020

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Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis.
Lisa Göschl, Teresa Preglej, Nicole Boucheron, Victoria Saferding, Lena Müller, Han-Yu Shih

J Autoimmun· March 2020

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Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation.
Hiroyuki Nagashima, Tanel Mahlakõiv, Han-Yu Shih, Fred P Davis, Francoise Meylan

Immunity· October 2019

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The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1.
Franziska Petermann, Aleksandra Pękowska, Catrina A Johnson, Dragana Jankovic, Han-Yu Shih

Mol Cell· September 2019

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Single-cell RNA-seq reveals TOX as a key regulator of CD8 T cell persistence in chronic infection.
Chen Yao, Hong-Wei Sun, Neal E Lacey, Yun Ji, E Ashley Moseman, Han-Yu Shih

Nat Immunol· July 2019

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Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium.
Tetsuro Kobayashi, Benjamin Voisin, Do Young Kim, Elizabeth A Kennedy, Jay-Hyun Jo, Han-Yu Shih

Cell· February 2019

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Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury.
Oliver J Harrison, Jonathan L Linehan, Han-Yu Shih, Nicolas Bouladoux, Seong-Ji Han

Science· January 2019

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Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology.
Daniella M Schwartz, Taylor K Farley, Nathan Richoz, Chen Yao, Han-Yu Shih

Immunity· January 2019

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Human retinoic acid-regulated CD161 regulatory T cells support wound repair in intestinal mucosa.
Giovanni A M Povoleri, Estefania Nova-Lamperti, Cristiano Scottà, Giorgia Fanelli, Yun-Ching Chen, Han-Yu Shih

Nat Immunol· December 2018

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