Publications by authors named "Hang Miao"

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Design, synthesis, structure-activity relationship (SAR) and analgesic effect studies of novel arylsulfonamides as selective Nav1.7 inhibitors.
Ruokun Wu, Wenfeng Chen, Xueyuan Wang, Xinran Ye, Hang Miao, Jingmiao Shi

Eur J Med Chem· December 2025

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Design and Discovery of Novel Selective RET Inhibitors with High Central Nervous System Penetration, Enhanced Pharmacokinetics, and Pharmacodynamics.
Xueyuan Wang, Hang Miao, Xinran Ye, Jingmiao Shi, Chunhuan Jiang

J Med Chem· July 2025

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Design and Synthesis of Novel 5,6,7,8-Tetrahydropyrido[2,3-]pyrimidine Derivatives as VCP/p97 Inhibitors for the Treatment of Acute Myeloid Leukemia (AML).
Xueyuan Wang, Zebo Long, Tiantian Wen, Hang Miao, Xinran Ye

Drug Des Devel Ther· June 2025

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Discovery of SZJK-0421: A Novel Potent, Low Toxicity, Selective Second Generation of CRM1 Inhibitor for the Treatment of Both Hematological and Solid Tumors.
Hang Miao, Yanru Qin, DingLu Shao, Qinghua Chen, Yupeng Pan

J Med Chem· November 2024

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Antitumor activity and low gastrointestinal toxicity of a novel selective inhibitor of nuclear export, SZJK-0421, in multiple myeloma.
Jing Wang, Hang Miao, Xuxing Shen, Lin Yang, Yongqiang Zhu

Acta Pharm Sin B· July 2024

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KPT-330 and Y219 exert a synergistic antitumor effect in triple-negative breast cancer through inhibiting NF-κB signaling.
Tiantian Wen, Mengzhu Geng, Enhe Bai, Xueyuan Wang, Hang Miao, Jingmiao Shi

FEBS Open Bio· April 2023

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Design and discovery of novel dipeptide boronic acid ester proteasome inhibitors, an oral slowly-released prodrug for the treatment of multiple myeloma.
Xueyuan Wang, Wen Zhang, Tiantian Wen, Hang Miao, Wenjiao Hu

Eur J Med Chem· March 2023

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Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of colorectal cancer.
Xueyuan Wang, Tiantian Wen, Hang Miao, Wenjiao Hu, Meng Lei

Bioorg Med Chem· November 2022

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Discovery of novel tripeptide propylene oxide proteasome inhibitors for the treatment of multiple myeloma.
Wen Zhang, Xueyuan Wang, Haoyang Zhang, Tiantian Wen, Lin Yang, Hang Miao

Bioorg Med Chem· June 2021

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Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors.
Meng Lei, Haoyang Zhang, Hang Miao, Xiao Du, Hui Zhou, Jingmiao Shi

Bioorg Med Chem· September 2019

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Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of non-small cell lung cancer.
Xueyuan Wang, Enhe Bai, Hui Zhou, Sijia Sha, Hang Miao

Bioorg Med Chem· February 2019

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Co-delivery of paclitaxel and gemcitabine a self-assembling nanoparticle for targeted treatment of breast cancer.
Meng Lei, Sijia Sha, Xueyuan Wang, Jia Wang, Xiao Du, Hang Miao, Jingmiao Shi

RSC Adv· February 2019

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