Publications by authors named "Hanny Fredrix"

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Intraperitoneal infusion of stem cell-derived natural killer cells in recurrent epithelial ovarian cancer patients: Results of the phase 1 INTRO-01 trial.
Janneke S Hoogstad-van Evert, Paul K J D de Jonge, Petra L M Zusterzeel, Willemijn Hobo, Anniek B van der Waart, Hanny Fredrix

Gynecol Oncol· November 2025

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PD-L1 siRNA-mediated silencing in acute myeloid leukemia enhances anti-leukemic T cell reactivity.
Diede van Ens, Charlotte M Mousset, Tim J A Hutten, Anniek B van der Waart, Diana Campillo-Davo, Hanny Fredrix

Bone Marrow Transplant· December 2020

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AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8 T cells for adoptive immunotherapy.
Charlotte M Mousset, Willemijn Hobo, Yun Ji, Hanny Fredrix, Valeria De Giorgi

Oncoimmunology· August 2018

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CLEC12A-Mediated Antigen Uptake and Cross-Presentation by Human Dendritic Cell Subsets Efficiently Boost Tumor-Reactive T Cell Responses.
Tim J A Hutten, Soley Thordardottir, Hanny Fredrix, Lisanne Janssen, Rob Woestenenk

J Immunol· October 2016

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siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8(+) T cells in NOD/SCID/IL2Rg(null) mice.
Anniek B van der Waart, Hanny Fredrix, Robbert van der Voort, Nicolaas Schaap, Willemijn Hobo

Cancer Immunol Immunother· May 2015

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Efficient nontoxic delivery of PD-L1 and PD-L2 siRNA into dendritic cell vaccines using the cationic lipid SAINT-18.
Mieke W H Roeven, Willemijn Hobo, Robbert van der Voort, Hanny Fredrix, Wieger J Norde

J Immunother· May 2015

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Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients.
Willemijn Hobo, Leonie Strobbe, Frans Maas, Hanny Fredrix, Annelies Greupink-Draaisma

Cancer Immunol Immunother· August 2013

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Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation.
Willemijn Hobo, Tatiana I Novobrantseva, Hanny Fredrix, Jamie Wong, Stuart Milstein

Cancer Immunol Immunother· February 2013

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Association of disparities in known minor histocompatibility antigens with relapse-free survival and graft-versus-host disease after allogeneic stem cell transplantation.
Willemijn Hobo, Kelly Broen, Walter J F M van der Velden, Annelies Greupink-Draaisma, Niken Adisty, Hanny Fredrix

Biol Blood Marrow Transplant· February 2013

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B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation.
Willemijn Hobo, Wieger J Norde, Nicolaas Schaap, Hanny Fredrix, Frans Maas

J Immunol· July 2012

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A polymorphism in the splice donor site of ZNF419 results in the novel renal cell carcinoma-associated minor histocompatibility antigen ZAPHIR.
Kelly Broen, Henriette Levenga, Johanna Vos, Kees van Bergen, Hanny Fredrix

PLoS One· December 2011

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Partial T cell-depleted allogeneic stem cell transplantation following reduced-intensity conditioning creates a platform for immunotherapy with donor lymphocyte infusion and recipient dendritic cell vaccination in multiple myeloma.
Henriëtte Levenga, Nicolaas Schaap, Frans Maas, Bennie Esendam, Hanny Fredrix

Biol Blood Marrow Transplant· March 2010

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Efficient activation of LRH-1-specific CD8+ T-cell responses from transplanted leukemia patients by stimulation with P2X5 mRNA-electroporated dendritic cells.
Ingrid M Overes, Hanny Fredrix, Michel G D Kester, J H Frederik Falkenburg, Robbert van der Voort

J Immunother· October 2009

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Myeloid leukemic progenitor cells can be specifically targeted by minor histocompatibility antigen LRH-1-reactive cytotoxic T cells.
Wieger J Norde, Ingrid M Overes, Frans Maas, Hanny Fredrix, Johanna C M Vos

Blood· March 2009

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Expression of P2X5 in lymphoid malignancies results in LRH-1-specific cytotoxic T-cell-mediated lysis.
Ingrid M Overes, Björn de Rijke, Agnes van Horssen-Zoetbrood, Hanny Fredrix, Aniek O de Graaf

Br J Haematol· June 2008

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Refinement of molecular approaches to improve the chance of identification of hematopoietic-restricted minor histocompatibility antigens.
Björn de Rijke, Agnes van Horssen-Zoetbrood, Sharon Veenbergen, Hanny Fredrix, Theo de Witte

J Immunol Methods· January 2008

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Generation of autologous cytotoxic and helper T-cell responses against the B-cell leukemia-associated antigen HB-1: relevance for precursor B-ALL-specific immunotherapy.
Bjorn de Rijke, Hanny Fredrix, Agnes Zoetbrood, Frank Scherpen, Henry Witteveen

Blood· October 2003

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Bi-directional allelic recognition of the human minor histocompatibility antigen HB-1 by cytotoxic T lymphocytes.
Harry Dolstra, Björn de Rijke, Hanny Fredrix, Antonio Balas, Frans Maas

Eur J Immunol· October 2002

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