Publications by authors named "Hanrui Yin"

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Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy.
Sijia Lu, Quanxin Jiang, Peihui Zhou, Limin Yin, Ning Wang, Hanrui Yin

J Adv Res· September 2025

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Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism.
Ning Wang, Sijia Lu, Ziyi Cao, Huimin Li, Junting Xu, Hanrui Yin, Limin Yin, Yingjie Xu

Cell Metab· June 2025

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Loss of insulin receptor isoform B impairs proinsulin processing in pancreatic β cells.
Hanrui Yin, Suzhen Chen, Junli Liu

Metabol Open· September 2024

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Intestinal activating transcription factor 4 regulates stress-related behavioral alterations via paraventricular thalamus in male mice.
Feixiang Yuan, Ziheng Zhou, Shangming Wu, Fuxin Jiao, Liang Chen, Hanrui Yin

Proc Natl Acad Sci U S A· May 2023

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Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.
Fei Xiao, Haizhou Jiang, Zi Li, Xiaoxue Jiang, Shanghai Chen, Hanrui Yin, Xiaoying Li

Nat Commun· May 2023

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Leucine deprivation results in antidepressant effects via GCN2 in AgRP neurons.
Feixiang Yuan, Shangming Wu, Ziheng Zhou, Fuxin Jiao, Hanrui Yin

Life Metab· February 2023

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SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
Xiaoxue Jiang, Kan Liu, Haizhou Jiang, Hanrui Yin, En-Duo Wang, Xiaoying Li

Cell Rep· January 2023

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Inhibition of c-Jun in AgRP neurons increases stress-induced anxiety and colitis susceptibility.
Fuxin Jiao, Xiaoming Hu, Hanrui Yin, Feixiang Yuan, Ziheng Zhou

Commun Biol· January 2023

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Amino acid sensor GCN2 promotes SARS-CoV-2 receptor ACE2 expression in response to amino acid deprivation.
Xiaoming Hu, Yuguo Niu, Peixiang Luo, Fei Xiao, Feixiang Yuan, Hanrui Yin

Commun Biol· July 2022

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Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
Yuguo Niu, Haizhou Jiang, Hanrui Yin, Fenfen Wang, Ronggui Hu

Diabetes· May 2022

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Intermittent Leucine Deprivation Produces Long-lasting Improvement in Insulin Sensitivity by Increasing Hepatic Gcn2 Expression.
Hanrui Yin, Feixiang Yuan, Fuxin Jiao, Yuguo Niu, Xiaoxue Jiang

Diabetes· February 2022

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Activation of GCN2 in macrophages promotes white adipose tissue browning and lipolysis under leucine deprivation.
Fenfen Wang, Fei Xiao, Linjuan Du, Yuguo Niu, Hanrui Yin

FASEB J· June 2021

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A fifty percent leucine-restricted diet reduces fat mass and improves glucose regulation.
Ziheng Zhou, Hanrui Yin, Yajie Guo, Yuanyuan Fang, Feixiang Yuan

Nutr Metab (Lond)· March 2021

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Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling.
Feixiang Yuan, Hanrui Yin, Yalan Deng, Fuxin Jiao, Haizhou Jiang, Hao Ying

Mol Metab· December 2020

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Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation.
Feixiang Yuan, Haizhou Jiang, Hanrui Yin, Xiaoxue Jiang, Fuxin Jiao, Hao Ying

Nat Commun· June 2020

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Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening.
Jiali Deng, Yajie Guo, Feixiang Yuan, Shanghai Chen, Hanrui Yin, Hao Ying

Autophagy· March 2020

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