Publications by authors named "Hans C Helms"

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Sortilin regulates blood-brain barrier integrity.
Andrea E Toth, Hans C Helms, Andras Harazin, Kasper B Johnsen, Charlotte Goldeman

FEBS J· February 2022

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Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins.
Lars Winkler, Rosel Blasig, Olga Breitkreuz-Korff, Philipp Berndt, Sophie Dithmer, Hans C Helms

J Cereb Blood Flow Metab· January 2021

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Evaluating the involvement of cerebral microvascular endothelial Na/K-ATPase and Na-K-2Cl co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration.
Kasper Lykke, Mette Assentoft, Sofie Hørlyck, Hans Cc Helms, Anca Stoica

J Cereb Blood Flow Metab· March 2019

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The insulin receptor is expressed and functional in cultured blood-brain barrier endothelial cells but does not mediate insulin entry from blood to brain.
Maria Hersom, Hans C Helms, Christoffer Schmalz, Thomas Å Pedersen, Stephen T Buckley

Am J Physiol Endocrinol Metab· October 2018

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Characterization of the L-glutamate clearance pathways across the blood-brain barrier and the effect of astrocytes in an in vitro blood-brain barrier model.
Hans Cc Helms, Blanca I Aldana, Simon Groth, Morten M Jensen, Helle S Waagepetersen

J Cereb Blood Flow Metab· December 2017

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Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers.
Maria Hersom, Hans Christian Helms, Natasia Pretzer, Charlotte Goldeman, Andreas I Jensen

Mol Cell Neurosci· October 2016

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In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.
Hans C Helms, N Joan Abbott, Malgorzata Burek, Romeo Cecchelli, Pierre-Olivier Couraud

J Cereb Blood Flow Metab· May 2016

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IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P-glycoprotein (ABCB1) for Drug Screening Studies.
Lasse Saaby, Hans Christian Cederberg Helms, Birger Brodin

Mol Pharm· February 2016

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Generation of primary cultures of bovine brain endothelial cells and setup of cocultures with rat astrocytes.
Hans C Helms, Birger Brodin

Methods Mol Biol· September 2014

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An electrically tight in vitro blood-brain barrier model displays net brain-to-blood efflux of substrates for the ABC transporters, P-gp, Bcrp and Mrp-1.
Hans Christian Helms, Maria Hersom, Louise Borella Kuhlmann, Lasina Badolo, Carsten Uhd Nielsen

AAPS J· September 2014

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In Vitro Membrane Permeation Studies and in Vivo Antinociception of Glycosylated Dmt-DALDA Analogues.
Steven Ballet, Cecilia Betti, Alexandre Novoa, Csaba Tömböly, Carsten Uhd Nielsen, Hans Christian Helms

ACS Med Chem Lett· April 2014

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In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells cocultured with astrocytes display a polarized brain-to-blood transport of glutamate.
Hans Christian Helms, Rasmus Madelung, Helle Sønderby Waagepetersen, Carsten Uhd Nielsen, Birger Brodin

Glia· May 2012

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Paracellular tightness and claudin-5 expression is increased in the BCEC/astrocyte blood-brain barrier model by increasing media buffer capacity during growth.
Hans Christian Helms, Helle Sønderby Waagepetersen, Carsten Uhd Nielsen, Birger Brodin

AAPS J· December 2010

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