Publications by authors named "Hans Princen"

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Low phylloquinone intake deteriorates endothelial function in normolipidemic and dyslipidaemic mice.
Agnieszka Kij, Anna Kieronska-Rudek, Anna Bar, Izabela Czyzynska-Cichon, Magdalena Strus, Hans M G Princen

J Nutr Biochem· June 2025

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Effects of life-long hyperlipidaemia on age-dependent development of endothelial dysfunction in humanised dyslipidaemic mice.
Anna Bar, Piotr Berkowicz, Anna Kurpinska, Tasnim Mohaissen, Agnieszka Karaś, Hans M G Princen

Geroscience· June 2025

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Fibrogenic Gene Signature as Early Prediction for the Efficacy of Pharmacological Interventions for MASH-Associated Fibrosis.
José A Inia, Martine C Morrison, Arianne van Koppen, Eveline Gart, Martien P M Caspers, Hans M G Princen

FASEB J· June 2025

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Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis.
José A Inia, Anita van Nieuwkoop-van Straalen, J Wouter Jukema, Bidda Rolin, Ellen Marie Staarup, Hans M G Princen

J Lipid Res· March 2025

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Therapeutic effects of FGF21 mimetic bFKB1 on MASH and atherosclerosis in Ldlr-/-.Leiden mice.
José A Inia, Joline Attema, Christa de Ruiter, Aswin L Menke, Martien P M Caspers, Hans M G Princen

FASEB J· October 2024

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Effects of repeated weight cycling on non-alcoholic steatohepatitis in diet-induced obese mice.
José A Inia, Jelle C B C de Jong, Nanda Keijzer, Aswin L Menke, Hans M G Princen

FASEB J· April 2024

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A systems toxicology approach for identification of disruptions in cholesterol homeostasis after aggregated exposure to mixtures of perfluorinated compounds in humans.
Joost Westerhout, Annemiek den Heijer-Jordaan, Hans M G Princen, Rob Stierum

Toxicol Sci· March 2024

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Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model.
Vanessa Zancanella, Astrid Vallès, Jolanda M P Liefhebber, Lieke Paerels, Carlos Vendrell Tornero, Hans Marinus Gerardus Princen

Mol Ther Nucleic Acids· June 2023

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Semaglutide Has Beneficial Effects on Non-Alcoholic Steatohepatitis in Ldlr-/-.Leiden Mice.
José A Inia, Geurt Stokman, Martine C Morrison, Nicole Worms, Lars Verschuren, Hans M G Princen

Int J Mol Sci· May 2023

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Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation.
José A Inia, Geurt Stokman, Elsbet J Pieterman, Martine C Morrison, Aswin L Menke, Hans M G Princen

Int J Mol Sci· April 2023

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A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo.
Alexandra K Suchowerska, Geurt Stokman, James T Palmer, Phillip A Coghlan, Elsbet J Pieterman, Hans M G Princen

J Lipid Res· November 2022

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The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis.
Miguel Carracedo, Sven-Christian Pawelzik, Gonzalo Artiach, Marianne G Pouwer, Oscar Plunde, Hans M G Princen

Br J Pharmacol· October 2022

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Chronic Oral Administration of Mineral Oil Compared With Corn Oil: Effects on Gut Permeability and Plasma Inflammatory and Lipid Biomarkers.
Elsbet J Pieterman, Hans M G Princen, Annica Jarke, Ralf Nilsson, Anders Cavallin

Front Pharmacol· August 2021

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Effects of mineral oil administration on the pharmacokinetics, metabolism and pharmacodynamics of atorvastatin and pravastatin in mice and dogs.
V Sashi Gopaul, Elsbet J Pieterman, Hans M G Princen, Linnéa Bergenholm, Eva Lundborg

Eur J Pharm Sci· June 2021

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Common Variants Associated With Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans.
Danielle van Keulen, Ian D van Koeverden, Arjan Boltjes, Hans M G Princen, Alain J van Gool

Front Cardiovasc Med· April 2021

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Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men.
Anita M van den Hoek, Lars Verschuren, Martien P M Caspers, Nicole Worms, Aswin L Menke, Hans M G Princen

Sci Rep· March 2021

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Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Styliani Fragki, Hubert Dirven, Tony Fletcher, Bettina Grasl-Kraupp, Kristine Bjerve Gützkow, Hans M G Princen

Crit Rev Toxicol· February 2021

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No effects of PCSK9-inhibitor treatment on spatial learning, locomotor activity, and novel object recognition in mice.
Frieder Schlunk, Paul Fischer, Hans M G Princen, Andre Rex, Vincent Prinz

Behav Brain Res· January 2021

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Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering.
Carmen Härdtner, Jan Kornemann, Katja Krebs, Carolin A Ehlert, Alina Jander, Hans M G Princen

Basic Res Cardiol· December 2020

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Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative.
Geurt Stokman, Anita M van den Hoek, Ditte Denker Thorbekk, Elsbet J Pieterman, Sanne Skovgård Veidal, Hans M G Princen

Liver Int· November 2020

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Effects of Inhibition or Deletion of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) on Intracerebral Hemorrhage Volumes in Mice.
Frieder Schlunk, Paul Fischer, Hans M G Princen, Andre Rex, Vincent Prinz

Stroke· November 2020

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In Vivo Magnetic Resonance Imaging-Based Detection of Heterogeneous Endothelial Response in Thoracic and Abdominal Aorta to Short-Term High-Fat Diet Ascribed to Differences in Perivascular Adipose Tissue in Mice.
Anna Bar, Anna Kieronska-Rudek, Bartosz Proniewski, Joanna Suraj-Prażmowska, Krzysztof Czamara, Hans M G Princen

J Am Heart Assoc· November 2020

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Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.
Danielle van Keulen, Marianne G Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J Pieterman, Hans M G Princen

PLoS One· March 2020

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Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice.
Marianne G Pouwer, Elsbet J Pieterman, Nicole Worms, Nanda Keijzer, J Wouter Jukema, Hans M G Princen

J Lipid Res· March 2020

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Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice.
Anita M van den Hoek, Elsbet J Pieterman, José W van der Hoorn, Marta Iruarrizaga-Lejarreta, Cristina Alonso, Hans M G Princen

Hepatol Commun· February 2020

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