Publications by authors named "Styliani Fragki"

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In vitro approaches to investigate the effect of chemicals on antibody production: the case study of PFASs.
Martina Iulini, Valeria Bettinsoli, Ambra Maddalon, Valentina Galbiati, Aafke W F Janssen, Styliani Fragki

Arch Toxicol· May 2025

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Advancing PFAS risk assessment: Integrative approaches using agent-based modelling and physiologically-based kinetic for environmental and health safety.
Martina Iulini, Giulia Russo, Elena Crispino, Alicia Paini, Styliani Fragki

Comput Struct Biotechnol J· December 2024

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Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells.
Jochem Louisse, Styliani Fragki, Deborah Rijkers, Aafke Janssen, Bas van Dijk

Arch Toxicol· April 2023

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New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs.
Styliani Fragki, Jochem Louisse, Bas Bokkers, Mirjam Luijten, Ad Peijnenburg

Food Chem Toxicol· February 2023

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Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Abdulkarim Najjar, Ans Punt, John Wambaugh, Alicia Paini, Corie Ellison, Styliani Fragki

Arch Toxicol· December 2022

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Applicability of generic PBK modelling in chemical hazard assessment: A case study with IndusChemFate.
Styliani Fragki, Aldert H Piersma, Joost Westerhout, Anne Kienhuis, Nynke I Kramer

Regul Toxicol Pharmacol· December 2022

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Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach.
Styliani Fragki, Rudolf Hoogenveen, Conny van Oostrom, Paul Schwillens, Aldert H Piersma

Toxicology· January 2022

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Response to Letter to the Editor on Bil et al. 2021 "Risk Assessment of Per- and Polyfluoroalkyl Substance Mixtures: A Relative Potency Factor Approach".
Wieneke Bil, Marco Zeilmaker, Styliani Fragki, Johannes Lijzen, Eric Verbruggen

Environ Toxicol Chem· January 2022

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Risk Assessment of Per- and Polyfluoroalkyl Substance Mixtures: A Relative Potency Factor Approach.
Wieneke Bil, Marco Zeilmaker, Styliani Fragki, Johannes Lijzen, Eric Verbruggen

Environ Toxicol Chem· March 2021

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Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Styliani Fragki, Hubert Dirven, Tony Fletcher, Bettina Grasl-Kraupp, Kristine Bjerve Gützkow

Crit Rev Toxicol· February 2021

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In vitro to in vivo extrapolation of effective dosimetry in developmental toxicity testing: Application of a generic PBK modelling approach.
Styliani Fragki, Aldert H Piersma, Emiel Rorije, Marco J Zeilmaker

Toxicol Appl Pharmacol· October 2017

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