Publications by authors named "Hans-Guenter Schaefer"

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Integration of absorption, distribution, metabolism, and elimination genotyping data into a population pharmacokinetic analysis of nevirapine.
Thorsten Lehr, Jing Yuan, David Hall, Heike Zimdahl-Gelling, Hans Guenter Schaefer

Pharmacogenet Genomics· November 2011

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Integration of high-throughput genotyping data into pharmacometric analyses using nonlinear mixed effects modeling.
Thorsten Lehr, Hans-Guenter Schaefer, Alexander Staab

Pharmacogenet Genomics· July 2010

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Quantitative pharmacology approach in Alzheimer's disease: efficacy modeling of early clinical data to predict clinical outcome of tesofensine.
Thorsten Lehr, Alexander Staab, Dirk Trommeshauser, Hans Guenter Schaefer, Charlotte Kloft

AAPS J· June 2010

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A quantitative enterohepatic circulation model: development and evaluation with tesofensine and meloxicam.
Thorsten Lehr, Alexander Staab, Christiane Tillmann, Dirk Trommeshauser, Hans-Guenter Schaefer

Clin Pharmacokinet· April 2010

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Semi-mechanistic population pharmacokinetic drug-drug interaction modelling of a long half-life substrate and itraconazole.
Thorsten Lehr, Alexander Staab, Dirk Trommeshauser, Hans Guenter Schaefer, Charlotte Kloft

Clin Pharmacokinet· February 2010

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Population pharmacokinetic modelling of NS2330 (tesofensine) and its major metabolite in patients with Alzheimer's disease.
Thorsten Lehr, Alexander Staab, Christiane Tillmann, Dirk Trommeshauser, Andreas Raschig, Hans Guenter Schaefer

Br J Clin Pharmacol· July 2007

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Effective integration of systems biology, biomarkers, biosimulation, and modeling in streamlining drug development.
Rajesh Krishna, Hans Guenter Schaefer, Ole J Bjerrum

J Clin Pharmacol· June 2007

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Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development.
Rajesh Krishna, Hans Guenter Schaefer, Ole J Bjerrum

Eur J Pharm Sci· May 2007

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Population pharmacokinetic modelling of BIBN 4096 BS, the first compound of the new class of calcitonin gene-related peptide receptor antagonists.
Iñaki F Trocóniz, Jan-Markus Wolters, Hans Guenter Schaefer, Willy Roth

Eur J Pharm Sci· July 2004

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