Publications by authors named "Hanxin Lin"

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BUB1B promotes homologous recombination‑mediated DNA damage repair in breast cancer cells through the PI3K/AKT signaling pathway.
Xuewen Luo, Yuqin Wei, Hanxin Lin, Ning Xiao, Wei Zhao

Oncol Rep· November 2025

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Clinical validation of a single NGS targeted panel pipeline using the KAPA HyperChoice system for detection of germline, somatic and mitochondrial sequence and copy number variants.
Jennifer Kerkhof, Cassandra Rastin, Laila Schenkel, Hanxin Lin, Bekim Sadikovic

Expert Rev Mol Diagn· October 2023

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Characterization of CCoV-HuPn-2018 spike protein-mediated viral entry.
Yongmei Liu, Danying Chen, Yuanyuan Wang, Xinglin Li, Yaruo Qiu, Hanxin Lin

J Virol· September 2023

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Molecular profiling of solid tumors by next-generation sequencing: an experience from a clinical laboratory.
Pratibha Bhai, Jacob Turowec, Stephanie Santos, Jennifer Kerkhof, LeeAnne Pickard, Hanxin Lin

Front Oncol· July 2023

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A Rational Approach to JAK2 Mutation Testing in Patients with Elevated Hemoglobin: Results from the JAK2 Prediction Cohort (JAKPOT) Study.
Benjamin Chin-Yee, Pratibha Bhai, Ian Cheong, Maxim Matyashin, Cyrus C Hsia, Hanxin Lin

J Gen Intern Med· June 2023

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Secondary causes of elevated hemoglobin in patients undergoing molecular testing for suspected polycythemia vera in southwestern Ontario: a chart review.
Benjamin Chin-Yee, Maxim Matyashin, Ian Cheong, Pratibha Bhai, Alejandro Lazo-Langner, Hanxin Lin

CMAJ Open· November 2022

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Mutational Landscape of Patients Referred for Elevated Hemoglobin Level.
Pratibha Bhai, Benjamin Chin-Yee, Victor Pope, Ian Cheong, Maxim Matyashin, Hanxin Lin

Curr Oncol· September 2022

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ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy.
Parisa Sooshtari, Biao Feng, Saumik Biswas, Michael Levy, Hanxin Lin

PLoS One· August 2022

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Clinical Utility of Implementing a Frontline NGS-Based DNA and RNA Fusion Panel Test for Patients with Suspected Myeloid Malignancies.
Pratibha Bhai, Cyrus C Hsia, Laila C Schenkel, Benjamin D Hedley, Michael A Levy, Hanxin Lin

Mol Diagn Ther· May 2022

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Reducing cytogenetic testing in the era of next generation sequencing: Are we choosing wisely?
Eri Kawata, Benjamin D Hedley, Benjamin Chin-Yee, Anargyros Xenocostas, Alejandro Lazo-Langner, Hanxin Lin

Int J Lab Hematol· April 2022

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Serum erythropoietin levels in 696 patients investigated for erythrocytosis with JAK2 mutation analysis.
Benjamin Chin-Yee, Ian Cheong, Maxim Matyashin, Alejandro Lazo-Langner, Ian Chin-Yee, Hanxin Lin

Am J Hematol· April 2022

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Lynch Syndrome Screening of Women with Endometrial Cancer: Feasibility and Outcomes in a Community Program.
Gulisa Turashvili, Terence Colgan, Meg McLachlin, Hanxin Lin, Robert Gharbharan

J Obstet Gynaecol Can· February 2022

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Cell Entry of Animal Coronaviruses.
Yang-Ran Cheng, Xinglin Li, Xuesen Zhao, Hanxin Lin

Viruses· October 2021

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Incidental findings from cancer next generation sequencing panels.
Nika Maani, Karen Panabaker, Jeanna M McCuaig, Kathleen Buckley, Kara Semotiuk, Hanxin Lin

NPJ Genom Med· July 2021

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Analysis of Sequence and Copy Number Variants in Canadian Patient Cohort With Familial Cancer Syndromes Using a Unique Next Generation Sequencing Based Approach.
Pratibha Bhai, Michael A Levy, Kathleen Rooney, Deanna Alexis Carere, Jack Reilly, Hanxin Lin

Front Genet· July 2021

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Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders.
Erfan Aref-Eshghi, Jennifer Kerkhof, Victor P Pedro, Groupe DI France, Mouna Barat-Houari, Damien Ulveling, Hanxin Lin

Am J Hum Genet· June 2021

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Clinical and technical assessment of MedExome vs. NGS panels in patients with suspected genetic disorders in Southwestern Ontario.
Erfan Aref-Eshghi, Jennifer Kerkhof, Deana Alexis Carere, Michael Volodarsky, Pratibha Bhai, Hanxin Lin

J Hum Genet· May 2021

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Comprehensive genetic sequence and copy number analysis for Charcot-Marie-Tooth disease in a Canadian cohort of 2517 patients.
Michael Volodarsky, Jennifer Kerkhof, Alan Stuart, Michael Levy, Lauren I Brady, Hanxin Lin

J Med Genet· April 2021

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Clinical value of next-generation sequencing compared to cytogenetics in patients with suspected myelodysplastic syndrome.
Eri Kawata, Alejandro Lazo-Langner, Anargyros Xenocostas, Cyrus C Hsia, Kang Howson-Jan, Hanxin Lin

Br J Haematol· February 2021

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Bat SARS-Like WIV1 coronavirus uses the ACE2 of multiple animal species as receptor and evades IFITM3 restriction TMPRSS2 activation of membrane fusion.
Mei Zheng, Xuesen Zhao, Shuangli Zheng, Danying Chen, Pengcheng Du, Xinglin Li, Hanxin Lin

Emerg Microbes Infect· December 2020

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Genetic and epigenetic profiling of BRCA1/2 in ovarian tumors reveals additive diagnostic yield and evidence of a genomic BRCA1/2 DNA methylation signature.
Erfan Aref-Eshghi, Jacob D McGee, Victor P Pedro, Jennifer Kerkhof, Alan Stuart, Hanxin Lin, Catherine Meg McLachlin

J Hum Genet· October 2020

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LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2.
Xuesen Zhao, Shuangli Zheng, Danying Chen, Mei Zheng, Xinglin Li, Hanxin Lin

J Virol· August 2020

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Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2.
Xuesen Zhao, Danying Chen, Robert Szabla, Mei Zheng, Guoli Li, Xinglin Li, Hanxin Lin

J Virol· August 2020

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Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders.
Erfan Aref-Eshghi, Jennifer Kerkhof, Victor P Pedro, , Mouna Barat-Houari, Damien Ulveling, Hanxin Lin

Am J Hum Genet· March 2020

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GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus.
Danying Chen, Zhifei Hou, Dong Jiang, Mei Zheng, Guoli Li, Hanxin Lin

Emerg Microbes Infect· January 2020

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