Publications by authors named "Harris D Bernstein"

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Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition.
Morgan E Walker, Wei Zhu, Janine H Peterson, Hao Wang, Jon Patteson, Harris D Bernstein

Nat Commun· April 2025

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Conserved lipid-facing basic residues promote the insertion of the porin OmpC into the outer membrane.
Janine H Peterson, Lixinhao Yang, James C Gumbart, Harris D Bernstein

mBio· March 2025

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Molecular Machines that Facilitate Bacterial Outer Membrane Protein Biogenesis.
Matthew Thomas Doyle, Harris D Bernstein

Annu Rev Biochem· August 2024

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The translocation assembly module (TAM) catalyzes the assembly of bacterial outer membrane proteins in vitro.
Xu Wang, Sarah B Nyenhuis, Harris D Bernstein

Nat Commun· August 2024

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The translocation assembly module (TAM) catalyzes the assembly of bacterial outer membrane proteins .
Xu Wang, Sarah B Nyenhuis, Harris D Bernstein

bioRxiv· June 2024

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The patatin-like protein PlpD forms structurally dynamic homodimers in the Pseudomonas aeruginosa outer membrane.
Sarah E Hanson, Tyrone Dowdy, Mioara Larion, Matthew Thomas Doyle, Harris D Bernstein

Nat Commun· May 2024

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The patatin-like protein PlpD forms novel structurally dynamic homodimers in the outer membrane.
Sarah E Hanson, Matthew Thomas Doyle, Harris D Bernstein

bioRxiv· April 2023

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Small Molecule Antibiotics Inhibit Distinct Stages of Bacterial Outer Membrane Protein Assembly.
Janine H Peterson, Matthew Thomas Doyle, Harris D Bernstein

mBio· October 2022

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Function of the Omp85 Superfamily of Outer Membrane Protein Assembly Factors and Polypeptide Transporters.
Matthew Thomas Doyle, Harris D Bernstein

Annu Rev Microbiol· September 2022

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The Escherichia coli outer membrane protein OmpA acquires secondary structure prior to its integration into the membrane.
Xu Wang, Harris D Bernstein

J Biol Chem· April 2022

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Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding.
Matthew Thomas Doyle, John R Jimah, Tyrone Dowdy, Shannon I Ohlemacher, Mioara Larion, Harris D Bernstein

Cell· March 2022

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Reconstitution of Bam Complex-Mediated Assembly of a Trimeric Porin into Proteoliposomes.
Sunyia Hussain, Janine H Peterson, Harris D Bernstein

mBio· August 2021

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BamA forms a translocation channel for polypeptide export across the bacterial outer membrane.
Matthew Thomas Doyle, Harris David Bernstein

Mol Cell· May 2021

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Bacterial Outer Membrane Proteins Are Targeted to the Bam Complex by Two Parallel Mechanisms.
Xu Wang, Janine H Peterson, Harris D Bernstein

mBio· May 2021

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A clostripain-like protease plays a major role in generating the secretome of enterotoxigenic Bacteroides fragilis.
Jessica V Pierce, Justin D Fellows, D Eric Anderson, Harris D Bernstein

Mol Microbiol· February 2021

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Bam complex-mediated assembly of bacterial outer membrane proteins synthesized in an in vitro translation system.
Sunyia Hussain, Janine H Peterson, Harris D Bernstein

Sci Rep· March 2020

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Chaperone OsmY facilitates the biogenesis of a major family of autotransporters.
Zhen Yan, Sunyia Hussain, Xu Wang, Harris D Bernstein, James C A Bardwell

Mol Microbiol· November 2019

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Sequential Translocation of Polypeptides across the Bacterial Outer Membrane through the Trimeric Autotransporter Pathway.
Rakesh Sikdar, Harris D Bernstein

mBio· October 2019

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Bacterial outer membrane proteins assemble via asymmetric interactions with the BamA β-barrel.
Matthew T Doyle, Harris D Bernstein

Nat Commun· July 2019

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Type V Secretion in Gram-Negative Bacteria.
Harris D Bernstein

EcoSal Plus· February 2019

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The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding.
Renuka Kudva, Pengfei Tian, Fátima Pardo-Avila, Marta Carroni, Robert B Best, Harris D Bernstein

Elife· November 2018

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Identification of a novel post-insertion step in the assembly of a bacterial outer membrane protein.
Janine H Peterson, Sunyia Hussain, Harris D Bernstein

Mol Microbiol· October 2018

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The Bam complex catalyzes efficient insertion of bacterial outer membrane proteins into membrane vesicles of variable lipid composition.
Sunyia Hussain, Harris D Bernstein

J Biol Chem· February 2018

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Selective pressure for rapid membrane integration constrains the sequence of bacterial outer membrane proteins.
Janine H Peterson, Ashlee M Plummer, Karen G Fleming, Harris D Bernstein

Mol Microbiol· December 2017

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Folding of a bacterial integral outer membrane protein is initiated in the periplasm.
Rakesh Sikdar, Janine H Peterson, D Eric Anderson, Harris D Bernstein

Nat Commun· November 2017

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