Publications by authors named "Harris Soifer"

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Ziftomenib in Relapsed or Refractory -Mutated AML.
Eunice S Wang, Pau Montesinos, James Foran, Harry Erba, Eduardo Rodríguez-Arbolí, Harris S Soifer

J Clin Oncol· November 2025

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Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial.
Eunice S Wang, Ghayas C Issa, Harry P Erba, Jessica K Altman, Pau Montesinos, Harris S Soifer

Lancet Oncol· October 2024

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Tipifarnib Potentiates the Antitumor Effects of PI3Kα Inhibition in PIK3CA- and HRAS-Dysregulated HNSCC via Convergent Inhibition of mTOR Activity.
Alison E Smith, Stacia Chan, Zhiyong Wang, Asako McCloskey, Quinn Reilly, Harris S Soifer

Cancer Res· October 2023

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Infigratinib in Patients with Recurrent Gliomas and FGFR Alterations: A Multicenter Phase II Study.
Andrew B Lassman, Juan Manuel Sepúlveda-Sánchez, Timothy F Cloughesy, Miguel J Gil-Gil, Vinay K Puduvalli, Harris S Soifer

Clin Cancer Res· June 2022

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Infigratinib (BGJ398) in previously treated patients with advanced or metastatic cholangiocarcinoma with FGFR2 fusions or rearrangements: mature results from a multicentre, open-label, single-arm, phase 2 study.
Milind Javle, Sameek Roychowdhury, Robin Kate Kelley, Saeed Sadeghi, Teresa Macarulla, Harris S Soifer

Lancet Gastroenterol Hepatol· October 2021

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Defining a Distinct Immunotherapy Eligible Subset of Patients with Cancer of Unknown Primary Using Gene Expression Profiling with the 92-Gene Assay.
Kanwal Raghav, Michael Overman, Graham M Poage, Harris S Soifer, Catherine A Schnabel

Oncologist· November 2020

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Infigratinib in upper tract urothelial carcinoma versus urothelial carcinoma of the bladder and its association with comprehensive genomic profiling and/or cell-free DNA results.
Sumanta K Pal, Dean Bajorin, Nazli Dizman, Jean Hoffman-Censits, David I Quinn, Harris S Soifer

Cancer· June 2020

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Performance and prognostic utility of the 92-gene assay in the molecular subclassification of ampullary adenocarcinoma.
Michael J Overman, Harris S Soifer, Aaron Joel Schueneman, Joe Ensor, Volkan Adsay

BMC Cancer· August 2016

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A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells.
Daniela Castanotto, Min Lin, Claudia Kowolik, LiAnn Wang, Xiao-Qin Ren, Harris S Soifer

Nucleic Acids Res· October 2015

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Antisense 2'-Deoxy, 2'-Fluroarabino Nucleic Acids (2'F-ANAs) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids.
Naira Souleimanian, Glen F Deleavey, Harris Soifer, Sijian Wang, Katrin Tiemann

Mol Ther Nucleic Acids· September 2012

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Silencing of gene expression by gymnotic delivery of antisense oligonucleotides.
Harris S Soifer, Troels Koch, Johnathan Lai, Bo Hansen, Anja Hoeg

Methods Mol Biol· March 2012

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Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells.
Harris S Soifer, Naira Souleimanian, Sijian Wu, Anatoliy M Voskresenskiy, Filiz Kisaayak Collak

J Biol Chem· February 2012

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Do small RNAs interfere with LINE-1?
Harris S Soifer

J Biomed Biotechnol· June 2010

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Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents.
C A Stein, J Bo Hansen, Johnathan Lai, SiJian Wu, Anatoliy Voskresenskiy, Harris S Soifer

Nucleic Acids Res· January 2010

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In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses.
Marcin Kortylewski, Piotr Swiderski, Andreas Herrmann, Lin Wang, Claudia Kowolik, Harris S Soifer

Nat Biotechnol· October 2009

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A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs.
Harris S Soifer, Masayuki Sano, Kumi Sakurai, Pritsana Chomchan, Pål Saetrom

Nucleic Acids Res· November 2008

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Chemical modification patterns compatible with high potency dicer-substrate small interfering RNAs.
Michael A Collingwood, Scott D Rose, Lingyan Huang, Chris Hillier, Mohammad Amarzguioui, Harris S Soifer

Oligonucleotides· June 2008

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MicroRNAs in disease and potential therapeutic applications.
Harris S Soifer, John J Rossi, Pål Saetrom

Mol Ther· December 2007

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Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC.
Daniela Castanotto, Kumi Sakurai, Robert Lingeman, Haitang Li, Louise Shively, Harris Soifer

Nucleic Acids Res· October 2007

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Small interfering RNAs to the rescue: blocking L1 retrotransposition.
Harris S Soifer, John J Rossi

Nat Struct Mol Biol· September 2006

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L1 retrotransposition in nondividing and primary human somatic cells.
Shuji Kubo, Maria Del Carmen Seleme, Harris S Soifer, José Luis Garcia Perez, John V Moran

Proc Natl Acad Sci U S A· May 2006

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A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon.
Harris S Soifer, Adriana Zaragoza, Maany Peyvan, Mark A Behlke, John J Rossi

Nucleic Acids Res· March 2005

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siRNA target site secondary structure predictions using local stable substructures.
Bret S E Heale, Harris S Soifer, Chauncey Bowers, John J Rossi

Nucleic Acids Res· February 2005

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A novel, helper-dependent, adenovirus-retrovirus hybrid vector: stable transduction by a two-stage mechanism.
Harris Soifer, Collin Higo, Christopher R Logg, Lily Ja-Lu Jih, Toshiaki Shichinohe

Mol Ther· May 2002

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