Publications by authors named "Hashim Motiwala"

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STX-721, a Covalent EGFR/HER2 Exon 20 Inhibitor, Utilizes Exon 20-Mutant Dynamic Protein States and Achieves Unique Mutant Selectivity Across Human Cancer Models.
Raymond A Pagliarini, Jack A Henderson, Benjamin C Milgram, Deanna R Borrelli, Natasja Brooijmans, Hashim Motiwala

Clin Cancer Res· July 2025

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Examining Kinetics and Product Inhibition in the Catalytic Intramolecular Schmidt Reaction.
Jackson G Cacioppo, Cole C Sorensen, Hashim F Motiwala, Jeffrey Aubé

J Org Chem· June 2025

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HFIP in Organic Synthesis.
Hashim F Motiwala, Ahlam M Armaly, Jackson G Cacioppo, Thomas C Coombs, Kimberly R K Koehn

Chem Rev· August 2022

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Tunable Heteroaromatic Sulfones Enhance in-Cell Cysteine Profiling.
Hashim F Motiwala, Yu-Hsuan Kuo, Brittany L Stinger, Bruce A Palfey, Brent R Martin

J Am Chem Soc· January 2020

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An Interrupted Schmidt Reaction: C-C Bond Formation Arising from Nitrilium Ion Capture.
Manwika Charaschanya, Kelin Li, Hashim F Motiwala, Jeffrey Aubé

Org Lett· October 2018

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Natural Withanolides in the Treatment of Chronic Diseases.
Peter T White, Chitra Subramanian, Hashim F Motiwala, Mark S Cohen

Adv Exp Med Biol· June 2017

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Chemoselective ratiometric imaging of protein S-sulfenylation.
Christopher T M B Tom, John E Crellin, Hashim F Motiwala, Matthew B Stone, Dahvid Davda

Chem Commun (Camb)· June 2017

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Trail-blAIZin new directions for conditional proteomics.
Hashim F Motiwala, Brent R Martin

Nat Methods· October 2016

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Synthesis and Biological Evaluation of Novobiocin Core Analogues as Hsp90 Inhibitors.
Katherine M Byrd, Chitra Subramanian, Jacqueline Sanchez, Hashim F Motiwala, Weiya Liu

Chemistry· May 2016

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Remodeling and Enhancing Schmidt Reaction Pathways in Hexafluoroisopropanol.
Hashim F Motiwala, Manwika Charaschanya, Victor W Day, Jeffrey Aubé

J Org Chem· February 2016

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Improved Schmidt Conversion of Aldehydes to Nitriles Using Azidotrimethylsilane in 1,1,1,3,3,3-Hexafluoro-2-propanol.
Hashim F Motiwala, Qin Yin, Jeffrey Aubé

Molecules· December 2015

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Intramolecular Friedel-Crafts Acylation Reaction Promoted by 1,1,1,3,3,3-Hexafluoro-2-propanol.
Hashim F Motiwala, Rakesh H Vekariya, Jeffrey Aubé

Org Lett· November 2015

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Synthesis and Cytotoxicity of Semisynthetic Withalongolide A Analogues.
Hashim F Motiwala, Joseph Bazzill, Abbas Samadi, Huaping Zhang, Barbara N Timmermann

ACS Med Chem Lett· November 2013

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Overcoming product inhibition in catalysis of the intramolecular Schmidt reaction.
Hashim F Motiwala, Charlie Fehl, Sze-Wan Li, Erin Hirt, Patrick Porubsky

J Am Chem Soc· June 2013

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Minor withanolides of Physalis longifolia: structure and cytotoxicity.
Huaping Zhang, Hashim Motiwala, Abbas Samadi, Victor Day, Jeffrey Aubé

Chem Pharm Bull (Tokyo)· March 2013

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Copper-catalyzed oxaziridine-mediated oxidation of C-H bonds.
Hashim F Motiwala, Belgin Gülgeze, Jeffrey Aubé

J Org Chem· August 2012

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Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.
Hashim Motiwala, Shivaji Kandre, Vishal Birar, Kishorkumar S Kadam, Atish Rodge

Bioorg Med Chem Lett· October 2011

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Progress in COX-2 inhibitors: a journey so far.
Asit K Chakraborti, Sanjeev K Garg, Raj Kumar, Hashim F Motiwala, Pradeep S Jadhavar

Curr Med Chem· July 2010

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Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat.
Lalit S Doshi, Manoja K Brahma, Sufyan G Sayyed, Amol V Dixit, Prakash G Chandak, Hashim F Motiwala

Metabolism· March 2009

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