Publications by authors named "Hasini Kalpage"

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Activity-Based Profiling of Reactive Nucleophilic Cysteine Sites from Tissue Proteomes for Drug Discovery Applications.
Hasini Kalpage, An Chi, Smaranda Bodea

Methods Mol Biol· June 2025

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Prostate Cancer-Specific Lysine 53 Acetylation of Cytochrome Drives Metabolic Reprogramming and Protects from Apoptosis in Intact Cells.
Paul T Morse, Junmei Wan, Tasnim Arroum, Mackenzie K Herroon, Hasini A Kalpage

Biomolecules· June 2024

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Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Paul T Morse, Gonzalo Pérez-Mejías, Junmei Wan, Alice A Turner, Inmaculada Márquez, Hasini A Kalpage

Nat Commun· July 2023

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Co-targeting of HDAC, PI3K, and Bcl-2 results in metabolic and transcriptional reprogramming and decreased mitochondrial function in acute myeloid leukemia.
Katie Hege Hurrish, Xinan Qiao, Xinyu Li, Yongwei Su, Jenna Carter, Hasini A Kalpage

Biochem Pharmacol· November 2022

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Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
Traci E LaMoia, Gina M Butrico, Hasini A Kalpage, Leigh Goedeke, Brandon T Hubbard

Proc Natl Acad Sci U S A· March 2022

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Lysine 53 Acetylation of Cytochrome in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis.
Viktoriia Bazylianska, Hasini A Kalpage, Junmei Wan, Asmita Vaishnav, Gargi Mahapatra

Cells· April 2021

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Germline mutations in apoptosis pathway genes in ovarian cancer; the functional role of a TP53I3 (PIG3) variant in ROS production and DNA repair.
Sophia R Chaudhry, Jaime Lopes, Nancy K Levin, Hasini Kalpage, Michael A Tainsky

Cell Death Discov· March 2021

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Targeting mitochondrial respiration for the treatment of acute myeloid leukemia.
Jenna L Carter, Katie Hege, Hasini A Kalpage, Holly Edwards, Maik Hüttemann

Biochem Pharmacol· December 2020

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Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy.
Jenna L Carter, Katie Hege, Jay Yang, Hasini A Kalpage, Yongwei Su

Signal Transduct Target Ther· December 2020

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Brain-Specific Serine-47 Modification of Cytochrome Regulates Cytochrome Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.
Hasini A Kalpage, Junmei Wan, Paul T Morse, Icksoo Lee, Maik Hüttemann

Cells· August 2020

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Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation.
Fangbing Liu, Hasini A Kalpage, Deying Wang, Holly Edwards, Maik Hüttemann

Cancers (Basel)· August 2020

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Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis.
Hasini A Kalpage, Junmei Wan, Paul T Morse, Matthew P Zurek, Alice A Turner

Int J Biochem Cell Biol· April 2020

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Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism.
Aamod S Dekhne, Changwen Ning, Md Junayed Nayeen, Khushbu Shah, Hasini Kalpage

Mol Pharmacol· January 2020

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Serine-47 phosphorylation of cytochrome in the mammalian brain regulates cytochrome oxidase and caspase-3 activity.
Hasini A Kalpage, Asmita Vaishnav, Jenney Liu, Ashwathy Varughese, Junmei Wan

FASEB J· December 2019

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Regulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation.
Junmei Wan, Hasini A Kalpage, Asmita Vaishnav, Jenney Liu, Icksoo Lee

Sci Rep· November 2019

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Tissue-specific regulation of cytochrome c by post-translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis.
Hasini A Kalpage, Viktoriia Bazylianska, Maurice A Recanati, Alemu Fite, Jenney Liu

FASEB J· February 2019

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Tissue- and Condition-Specific Isoforms of Mammalian Cytochrome Oxidase Subunits: From Function to Human Disease.
Christopher A Sinkler, Hasini Kalpage, Joseph Shay, Icksoo Lee, Moh H Malek

Oxid Med Cell Longev· March 2018

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Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability.
Jaime L Stafford, Gregory Dyson, Nancy K Levin, Sophia Chaudhry, Rita Rosati, Hasini Kalpage

PLoS One· September 2017

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A Study on Hereditary Thrombophilia and Stroke in a Cohort from Sri Lanka.
Hasini A Kalpage, Dulika S Sumathipala, Hemali W Goonasekara, Vajira H Dissanayake

J Stroke Cerebrovasc Dis· January 2016

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