Publications by authors named "Hassan Issafras"

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Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy.
Hassan Issafras, Shilong Fan, Chi-Ling Tseng, Yunchih Cheng, Peihua Lin

PLoS One· January 2022

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Distinguishing features of a novel humanized anti-EGFR monoclonal antibody based on cetuximab with superior antitumor efficacy.
Pei-Hua Lin, Chi-Ling Tseng, Yun-Chih Cheng, Chieh-Hsin Ho, Shih Chieh Chen, Hassan Issafras

Expert Opin Biol Ther· November 2021

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Characterization of murine CEACAM1 reveals low expression on CD8 T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1.
Robbie L McLeod, Minilik H Angagaw, Toya Nath Baral, Liming Liu, Raymond Joseph Moniz, Hassan Issafras

Oncotarget· October 2018

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Application of an In Vivo Hepatic Triacylglycerol Production Method in the Setting of a High-Fat Diet in Mice.
Kikumi D Ono-Moore, Matthew Ferguson, Michael L Blackburn, Hassan Issafras, Sean H Adams

Nutrients· December 2016

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Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia.
John A Corbin, Vinay Bhaskar, Ira D Goldfine, Hassan Issafras, Daniel H Bedinger

MAbs· October 2014

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Selective allosteric antibodies to the insulin receptor for the treatment of hyperglycemic and hypoglycemic disorders.
Hassan Issafras, Daniel H Bedinger, John A Corbin, Ira D Goldfine, Vinay Bhaskar

J Diabetes Sci Technol· July 2014

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Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1β antibody with differential receptor-modulating properties.
Hassan Issafras, John A Corbin, Ira D Goldfine, Marina K Roell

J Pharmacol Exp Ther· January 2014

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Enhancement of antibody fragment secretion into the Escherichia coli periplasm by co-expression with the peptidyl prolyl isomerase, FkpA, in the cytoplasm.
Raphael Levy, Kiran Ahluwalia, David J Bohmann, Hoa M Giang, Lauren J Schwimmer, Hassan Issafras

J Immunol Methods· August 2013

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XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases.
Alexander M Owyang, Hassan Issafras, John Corbin, Kiran Ahluwalia, Paul Larsen

MAbs· July 2011

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Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice.
Vinay Bhaskar, Johnny Yin, Amer M Mirza, Dan Phan, Sandra Vanegas, Hassan Issafras

Atherosclerosis· June 2011

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Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity.
Marina K Roell, Hassan Issafras, Robert J Bauer, Kristen S Michelson, Nerissa Mendoza

J Biol Chem· July 2010

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Homo- and hetero-oligomerization of beta-arrestins in living cells.
Hélène Storez, Mark G H Scott, Hassan Issafras, Anne Burtey, Alexandre Benmerah

J Biol Chem· December 2005

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Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors.
Hassan Issafras, Stéphane Angers, Sébastien Bulenger, Cédric Blanpain, Marc Parmentier

J Biol Chem· September 2002

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Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies.
Cédric Blanpain, Jean-Marie Vanderwinden, Josef Cihak, Valérie Wittamer, Emmanuel Le Poul, Hassan Issafras

Mol Biol Cell· February 2002

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