Publications by authors named "Hayley Muendlein"

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Tregs epigenetically reprogrammed from autoreactive effector T cells mitigate established autoimmunity.
Tyler R Colson, James J Cameron, Hayley I Muendlein, Mei-An Nolan, Jamie L Leiriao

JCI Insight· September 2025

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Regulatory T cells epigenetically reprogrammed from autoreactive effector T cells mitigate established autoimmunity.
Tyler R Colson, James J Cameron, Hayley I Muendlein, Mei-An Nolan, Jamie L Leiriao

bioRxiv· July 2025

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TNF switches homeostatic efferocytosis to lytic caspase-8-dependent pyroptosis and IL-1β maturation.
Hayley I Muendlein, Wilson M Connolly, Jamie Leiriao, Mei-An Nolan, Jennifer Judge

Sci Immunol· June 2025

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MyD88 determines T cell fate through BCAP-PI3K signaling.
Abraham L Bayer, Zoie Magri, Hayley Muendlein, Alexander Poltorak, Pilar Alcaide

J Immunol· March 2025

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Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair.
Kautilya K Jena, Julien Mambu, Daniel Boehmer, Benedetta Sposito, Virginie Millet, Hayley I Muendlein

Cell· December 2024

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CD14 is a decision-maker between Fas-mediated death and inflammation.
Zoie Magri, David Jetton, Hayley I Muendlein, Wilson M Connolly, Hunter Russell

Cell Rep· September 2024

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Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection.
David Jetton, Hayley I Muendlein, Wilson M Connolly, Zoie Magri, Irina Smirnova

Cell Rep· August 2024

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Neutrophils and macrophages drive TNF-induced lethality via TRIF/CD14-mediated responses.
Hayley I Muendlein, Wilson M Connolly, James Cameron, David Jetton, Zoie Magri

Sci Immunol· December 2022

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ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF.
Hayley I Muendlein, Wilson M Connolly, Zoie Magri, David Jetton, Irina Smirnova

Proc Natl Acad Sci U S A· June 2022

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LFA-1 and kindlin-3 enable the collaborative transport of SLP-76 microclusters by myosin and dynein motors.
Keith P Eidell, Alenka Lovy, Nicholas R Sylvain, Frank A Scangarello, Hayley I Muendlein

J Cell Sci· August 2021

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Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages.
Ioannis Siokas, Dingqiang Zhang, Alexander Poltorak, Hayley Muendlein, Alexei Degterev

Curr Protoc· June 2021

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ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1.
Hayley I Muendlein, Wilson M Connolly, Zoie Magri, Irina Smirnova, Vladimir Ilyukha

Nat Commun· January 2021

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Flipping the Switch from Inflammation to Cell Death.
Hayley I Muendlein, Alexander Poltorak

Trends Immunol· August 2020

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cFLIP protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation.
Hayley I Muendlein, David Jetton, Wilson M Connolly, Keith P Eidell, Zoie Magri

Science· March 2020

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Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation.
Hayley I Muendlein, Joseph Sarhan, Beiyun C Liu, Wilson M Connolly, Stephen A Schworer

Cell Rep· January 2020

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Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
Joseph Sarhan, Beiyun C Liu, Hayley I Muendlein, Chi G Weindel, Irina Smirnova

Cell Death Differ· January 2019

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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during infection.
Joseph Sarhan, Beiyun C Liu, Hayley I Muendlein, Peng Li, Rachael Nilson

Proc Natl Acad Sci U S A· November 2018

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Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses.
Beiyun C Liu, Joseph Sarhan, Alexander Panda, Hayley I Muendlein, Vladimir Ilyukha

Cell Rep· July 2018

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