Publications by authors named "Heather Fifield"

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Structure-Based Design of First-Generation Small Molecule Inhibitors Targeting the Catalytic Pockets of AID, APOBEC3A, and APOBEC3B.
Justin J King, Faezeh Borzooee, Junbum Im, Mahdi Asgharpour, Atefeh Ghorbani, Heather Fifield

ACS Pharmacol Transl Sci· August 2021

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Activation-induced cytidine deaminase can target multiple topologies of double-stranded DNA in a transcription-independent manner.
Sarah A Branton, Atefeh Ghorbani, Brittany N Bolt, Heather Fifield, Lesley M Berghuis

FASEB J· July 2020

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AID, APOBEC3A and APOBEC3B efficiently deaminate deoxycytidines neighboring DNA damage induced by oxidation or alkylation.
Cody P Diamond, Junbum Im, Erynn A Button, David N G Huebert, Justin J King, Heather Fifield

Biochim Biophys Acta Gen Subj· November 2019

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Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys.
Stephen J Holland, Lesley M Berghuis, Justin J King, Lakshminarayan M Iyer, Katarzyna Sikora, Heather Fifield

Proc Natl Acad Sci U S A· April 2018

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A licensing step links AID to transcription elongation for mutagenesis in B cells.
Stephen P Methot, Ludivine C Litzler, Poorani Ganesh Subramani, Anil K Eranki, Heather Fifield

Nat Commun· March 2018

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DNA/RNA hybrid substrates modulate the catalytic activity of purified AID.
Hala S Abdouni, Justin J King, Atefeh Ghorbani, Heather Fifield, Lesley Berghuis

Mol Immunol· January 2018

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Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.
Astrid Zahn, Anil K Eranki, Anne-Marie Patenaude, Stephen P Methot, Heather Fifield

Proc Natl Acad Sci U S A· March 2014

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Zebrafish AID is capable of deaminating methylated deoxycytidines.
Hala Abdouni, Justin J King, Mussa Suliman, Matthew Quinlan, Heather Fifield

Nucleic Acids Res· May 2013

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Differences in the enzymatic efficiency of human and bony fish AID are mediated by a single residue in the C terminus modulating single-stranded DNA binding.
Alex M Dancyger, Justin J King, Matthew J Quinlan, Heather Fifield, Stephanie Tucker

FASEB J· April 2012

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