Publications by authors named "Hector DeLuca"

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Design, synthesis, and biological activity of D-bishomo-1α,25-dihydroxyvitamin D analogs and their crystal structures with the vitamin D nuclear receptor.
Adrian Fabisiak, Pawel Brzeminski, Rafal R Sicinski, Natacha Rochel, Ewa Maj, Hector F DeLuca

Eur J Med Chem· May 2024

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Antibody production in mice requires neither vitamin D, nor the vitamin D receptor.
Lori A Plum, William Blaser, Logan Peter, Jean Prahl, Jeremy Seeman, Hector F DeLuca

Front Immunol· November 2022

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Vitamin D esters are the major form of vitamin D produced by UV irradiation in mice.
Elizabeth G Duchow, Izabela K Sibilska-Kaminski, Lori A Plum, Hector F DeLuca

Photochem Photobiol Sci· August 2022

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Vitamin D receptor absence does not enhance intestinal tumorigenesis in ApcPirc/+rats.
Amy A Irving, Bayley J Waters, Jeremy R Seeman, Lori A Plum, Hector F DeLuca

Biol Open· July 2022

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Novel superagonist analogs of 2-methylene calcitriol: Design, molecular docking, synthesis and biological evaluation.
Izabela K Sibilska-Kaminski, Adrian Fabisiak, Pawel Brzeminski, Lori A Plum, Rafal R Sicinski, Hector F DeLuca

Bioorg Chem· January 2022

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Vitamin D binding protein greatly improves bioactivity but is not essential for orally administered vitamin D.
Elizabeth G Duchow, Mark W Duchow, Lori A Plum, Hector F DeLuca

Physiol Rep· December 2021

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Synthesis and Biological Activity of 2,22-Dimethylene Analogues of 19-Norcalcitriol and Related Compounds.
Izabela K Sibilska-Kaminski, Rafal R Sicinski, Lori A Plum, Hector F DeLuca

J Med Chem· July 2020

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A New 1,25 Dihydroxy Vitamin D Analog with Strong Bone Anabolic Activity in OVX Rats with Little or no Bone Resorptive Activity.
Lori A Plum, Julia Zella, Margaret Clagett-Dame, Hector F DeLuca

J Bone Miner Res· April 2020

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Vitamin D binding protein is required to utilize skin-generated vitamin D.
Elizabeth G Duchow, Nancy E Cooke, Jeremy Seeman, Lori A Plum, Hector F DeLuca

Proc Natl Acad Sci U S A· December 2019

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UV light suppression of EAE (a mouse model of multiple sclerosis) is independent of vitamin D and its receptor.
Amy A Irving, Steven J Marling, Jeremy Seeman, Lori A Plum, Hector F DeLuca

Proc Natl Acad Sci U S A· November 2019

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Vitamin D is not required for adaptive immunity to listeria.
Gary A Baisa, Lori Plum, Steve Marling, Jeremy Seeman, Hector F DeLuca

Physiol Rep· August 2019

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Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D.
Christopher T Sempos, Annemieke C Heijboer, Daniel D Bikle, Jens Bollerslev, Roger Bouillon, Hector F DeLuca

Br J Clin Pharmacol· October 2018

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Vitamin D deficiency in the rat does not exacerbate colonic tumorigenesis, while low dietary calcium might be protective.
Amy A Irving, Elizabeth G Duchow, Lori A Plum, Hector F DeLuca

Dis Model Mech· March 2018

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2MD (DP001), a Single Agent in the Management of Hemodialysis Patients: A Randomized Trial.
Ravi Thadhani, Julia B Zella, Danielle C Knutson, William J Blaser, Lori A Plum, Hector F DeLuca

Am J Nephrol· January 2018

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Pharmacokinetics of a New Oral Vitamin D Receptor Activator (2-Methylene-19-Nor-(20S)-1α,25-Dihydroxyvitamin D) in Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism on Hemodialysis.
Richa Pandey, Julia B Zella, Jinge G Zhu, Lori A Plum, Margaret Clagett-Dame, Hector F DeLuca

Drugs R D· December 2017

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Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid.
Jamie M Ahrens, James D Jones, Nirca J Nieves, Ann M Mitzey, Hector F DeLuca

PLoS One· December 2017

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Effects of the Vitamin D Analog 2AMD in Cyclosporine-Induced Nephrotoxicity: Dose-Response and Antifibrotic Activity.
Bianca Tomasini-Johansson, Cori O'Brien, Alexandra Larson-Osborne, Inger Toraason, Debra Hullett, Hector DeLuca

Exp Clin Transplant· December 2017

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D-seco-Vitamin D analogs having reversed configurations at C-13 and C-14: Synthesis, docking studies and biological evaluation.
Marcin Szybinski, Katarzyna Sokolowska, Rafal R Sicinski, Lori A Plum, Hector F DeLuca

J Steroid Biochem Mol Biol· October 2017

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Analysis of the binding sites of vitamin D 1α-hydroxylase (CYP27B1) and vitamin D 24-hydroxylase (CYP24A1) for the design of selective CYP24A1 inhibitors: Homology modelling, molecular dynamics simulations and identification of key binding requirements.
Ismail M Taban, Jinge Zhu, Hector F DeLuca, Claire Simons

Bioorg Med Chem· October 2017

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Synthesis, molecular modelling and CYP24A1 inhibitory activity of novel of (E)-N-(2-(1H-imidazol-1-yl)-2-(phenylethyl)-3/4-styrylbenzamides.
Ismail M Taban, Jinge Zhu, Hector F DeLuca, Claire Simons

Bioorg Med Chem· August 2017

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Salate derivatives found in sunscreens block experimental autoimmune encephalomyelitis in mice.
Yanping Wang, Steven J Marling, Lori A Plum, Hector F DeLuca

Proc Natl Acad Sci U S A· August 2017

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Design, synthesis and biological properties of seco-d-ring modified 1α,25-dihydroxyvitamin D analogues.
Marcin Szybinski, Katarzyna Sektas, Rafal R Sicinski, Lori A Plum, Jadwiga Frelek, Hector F DeLuca

J Steroid Biochem Mol Biol· July 2017

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Suppression of experimental autoimmune encephalomyelitis by ultraviolet light is not mediated by isomerization of urocanic acid.
Amy A Irving, Steven J Marling, Lori A Plum, Hector F DeLuca

BMC Neurosci· January 2017

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The absence of 25-hydroxyvitamin D3-1α-hydroxylase potentiates the suppression of EAE in mice by ultraviolet light.
Yanping Wang, Steve J Marling, Victoria M Martino, Jean M Prahl, Hector F Deluca

J Steroid Biochem Mol Biol· October 2016

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The association of mineral metabolism with vascular access patency.
Joel E Rosenberg, Brad C Astor, Hector F Deluca, Alexander S Yevzlin

J Vasc Access· September 2016

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