Publications by authors named "Heekyoung Yang"

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The semaphorin 3A/neuropilin-1 pathway promotes clonogenic growth of glioblastoma via activation of TGF-β signaling.
Hye-Min Jeon, Yong Jae Shin, Jaehyun Lee, Nakho Chang, Dong-Hun Woo, Heekyoung Yang

JCI Insight· November 2023

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Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5.
Hye-Min Jeon, Young Taek Oh, Yong Jae Shin, Nakho Chang, Donggeun Kim, Heekyoung Yang

Neoplasia· May 2023

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Targeted Delivery of Exosomes Armed with Anti-Cancer Therapeutics.
Hojun Choi, Hwayoung Yim, Cheolhyoung Park, So-Hee Ahn, Yura Ahn, Heekyoung Yang

Membranes (Basel)· January 2022

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Correction: Secretome analysis of patient-derived GBM tumorspheres identifies midkine as a potent therapeutic target.
Suji Han, Hyemi Shin, Jin-Ku Lee, Zhaoqi Liu, Raul Rabadan, Heekyoung Yang

Exp Mol Med· November 2020

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Therapeutic Efficacy of GC1118, a Novel Anti-EGFR Antibody, against Glioblastoma with High EGFR Amplification in Patient-Derived Xenografts.
Kyoungmin Lee, Harim Koo, Yejin Kim, Donggeon Kim, Eunju Son, Heekyoung Yang, Yangmi Lim

Cancers (Basel)· October 2020

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Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target.
Suji Han, Hyemi Shin, Jin-Ku Lee, Zhaoqi Liu, Raul Rabadan, Heekyoung Yang

Exp Mol Med· December 2019

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Synthesis and biological evaluation of potent benzoselenophene and heteroaromatic analogues of ()-1-(chloromethyl)-8-methoxy-2,3-dihydro-1-benzo[]indol-5-ol (-MCBI).
Amol B Mhetre, Eppakayala Sreedhar, Rashmi Dubey, Ganesh A Sable, Hangeun Lee, Heekyoung Yang

RSC Adv· September 2019

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Relevance of a TCGA-derived Glioblastoma Subtype Gene-Classifier among Patient Populations.
Wan-Yee Teo, Karthik Sekar, Pratap Seshachalam, Jianhe Shen, Wing-Yuk Chow, HeeKyoung Yang

Sci Rep· May 2019

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Synthesis and anticancer activity of benzoselenophene and heteroaromatic derivatives of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI).
Amol B Mhetre, Hangeun Lee, Heekyoung Yang, Kyoungmin Lee, Do-Hyun Nam

Org Biomol Chem· February 2017

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Anticancer activity of TTAC-0001, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) monoclonal antibody, is associated with inhibition of tumor angiogenesis.
Dong Geon Kim, Younggeon Jin, Juyoun Jin, Heekyoung Yang, Kyeung Min Joo

MAbs· August 2016

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Anti-miR delivery strategies to bypass the blood-brain barrier in glioblastoma therapy.
Dong Geon Kim, Kang Ho Kim, Yun Jee Seo, Heekyoung Yang, Eric G Marcusson

Oncotarget· May 2016

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Facilitating tailored therapeutic strategies for glioblastoma through an orthotopic patient-derived xenograft platform.
Hye Won Lee, Kyoungmin Lee, Dong Geon Kim, HeeKyoung Yang, Do-Hyun Nam

Histol Histopathol· March 2016

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GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands.
Yangmi Lim, Jiho Yoo, Min-Soo Kim, Minkyu Hur, Eun Hee Lee, Heekyoung Yang

Mol Cancer Ther· February 2016

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USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance.
Jin-Ku Lee, Nakho Chang, Yeup Yoon, Heekyoung Yang, Heejin Cho

Neuro Oncol· January 2016

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Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).
Ahmed Elkamhawy, Ambily Nath Indu Viswanath, Ae Nim Pae, Hyeon Young Kim, Jin-Chul Heo, Heekyoung Yang

Eur J Med Chem· October 2015

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KML001, a telomere-targeting drug, sensitizes glioblastoma cells to temozolomide chemotherapy and radiotherapy through DNA damage and apoptosis.
Seon Rang Woo, Yunhee Ham, Wonyoung Kang, Heekyoung Yang, Sujong Kim

Biomed Res Int· June 2015

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Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing.
Tao Xie, Yong Beom Cho, Kai Wang, Donghui Huang, Hye Kyung Hong, Heekyoung Yang

Genomics· October 2014

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TopBP1 and Claspin contribute to the radioresistance of lung cancer brain metastases.
Seung Ho Choi, Heekyoung Yang, Seung Ho Lee, Joo-Hyun Ki, Do-Hyun Nam

Mol Cancer· September 2014

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Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction.
Dae Gyu Kim, Jin Young Lee, Nam Hoon Kwon, Pengfei Fang, Qian Zhang, Heekyoung Yang, Jee Sun Yang, Won Suk Yang

Nat Chem Biol· January 2014

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Genetically-engineered human neural stem cells with rabbit carboxyl esterase can target CNS lymphoma.
Wonyoung Kang, Juyoun Jin, Heekyoung Yang, Ho Jun Seol, Kang Ho Kim

Anticancer Res· December 2013

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Radiosensitization of brain metastasis by targeting c-MET.
Heekyoung Yang, Hye Won Lee, Yonghyun Kim, Yeri Lee, Yeon-Sook Choi

Lab Invest· March 2013

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Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ.
Kyeung Min Joo, Jinkuk Kim, Juyoun Jin, Misuk Kim, Ho Jun Seol, Heekyoung Yang, Woong-Yang Park

Cell Rep· January 2013

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Trans-differentiation of neural stem cells: a therapeutic mechanism against the radiation induced brain damage.
Kyeung Min Joo, Juyoun Jin, Bong Gu Kang, Se Jeong Lee, Kang Ho Kim, Heekyoung Yang

PLoS One· July 2012

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Wnt activation is implicated in glioblastoma radioresistance.
Yonghyun Kim, Kang Ho Kim, Jeena Lee, Young-Ae Lee, Misuk Kim, Heekyoung Yang

Lab Invest· March 2012

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In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles.
Juyoun Jin, Ki Hyun Bae, Heekyoung Yang, Se Jeong Lee, Hyein Kim

Bioconjug Chem· December 2011

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