Publications by authors named "Heidi Baum"

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HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis.
Takayuki Ikeda, Sungki Hong, Shota Yoshida, Swayam Prakash Srivastava, Abhiram Kunamneni, Heidi Baum

Cell Rep· October 2025

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Correction: Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, Sebastian M Waszak, Stefan R Sweha, Heidi Baum

Cancer Discov· March 2025

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Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation.
Vasundhara Kain, Kevin A Ingle, Maureen Kachman, Heidi Baum, Gobinath Shanmugam

Am J Physiol Heart Circ Physiol· February 2018

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Dissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientations.
Jana Streubel, Heidi Baum, Jan Grau, Johannes Stuttmann, Jens Boch

PLoS One· September 2017

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Correction: Dissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientations.
Jana Streubel, Heidi Baum, Jan Grau, Johannes Stuttmann, Jens Boch

PLoS One· April 2017

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Patient-adapted, specific activation of HIV-1 by customized TAL effectors (TALEs), a proof of principle study.
Rene Geissler, Ilona Hauber, Nancy Funk, Annekatrin Richter, Martina Behrens, Heidi Baum

Virology· December 2015

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Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, part I: transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors.
Mark S Plummer, Joseph Cornicelli, Howard Roark, Donald J Skalitzky, Charles J Stankovic, Heidi Baum

Bioorg Med Chem Lett· June 2013

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Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: optimization studies and demonstration of in vivo efficacy.
Mark S Plummer, Joseph Cornicelli, Howard Roark, Donald J Skalitzky, Charles J Stankovic, Heidi Baum

Bioorg Med Chem Lett· June 2013

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N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-D-aspartate receptor antagonists for the treatment of pain.
Christopher Deur, Arun K Agrawal, Heidi Baum, John Booth, Susan Bove

Bioorg Med Chem Lett· August 2007

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