Publications by authors named "Heidy Zinger"

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Indoleamine-2,3-dioxygenase in murine and human systemic lupus erythematosus: Down-regulation by the tolerogeneic peptide hCDR1.
Zev Sthoeger, Amir Sharabi, Heidy Zinger, Ilan Asher, Edna Mozes

Clin Immunol· December 2018

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The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients.
Zev Sthoeger, Amir Sharabi, Ilan Asher, Heidy Zinger, Rafael Segal

Clin Immunol· July 2018

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The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus.
Zev Sthoeger, Heidy Zinger, Amir Sharabi, Ilan Asher, Edna Mozes

PLoS One· September 2013

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Induction of hippocampal neurogenesis by a tolerogenic peptide that ameliorates lupus manifestations.
Alona Telerman, Smadar Lapter, Amir Sharabi, Heidy Zinger, Edna Mozes

J Neuroimmunol· March 2011

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A role for the B-cell CD74/macrophage migration inhibitory factor pathway in the immunomodulation of systemic lupus erythematosus by a therapeutic tolerogenic peptide.
Smadar Lapter, Hava Ben-David, Amir Sharabi, Heidy Zinger, Alona Telerman

Immunology· January 2011

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A new model of induced experimental systemic lupus erythematosus (SLE) in pigs and its amelioration by treatment with a tolerogenic peptide.
Amir Sharabi, Molly Dayan, Heidy Zinger, Edna Mozes

J Clin Immunol· January 2010

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In vivo dynamical interactions between CD4 Tregs, CD8 Tregs and CD4+ CD25- cells in mice.
Arnon Arazi, Amir Sharabi, Heidy Zinger, Edna Mozes, Avidan U Neumann

PLoS One· December 2009

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A tolerogenic peptide that induces suppressor of cytokine signaling (SOCS)-1 restores the aberrant control of IFN-gamma signaling in lupus-affected (NZB x NZW)F1 mice.
Amir Sharabi, Zev M Sthoeger, Keren Mahlab, Smadar Lapter, Heidy Zinger

Clin Immunol· October 2009

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A tolerogenic peptide down-regulates mature B cells in bone marrow of lupus-afflicted mice by inhibition of interleukin-7, leading to apoptosis.
Hava Ben-David, Amir Sharabi, Reshmi Parameswaran, Heidy Zinger, Edna Mozes

Immunology· October 2009

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Treatment of lupus patients with a tolerogenic peptide, hCDR1 (Edratide): immunomodulation of gene expression.
Zev M Sthoeger, Amir Sharabi, Yair Molad, Ilan Asher, Heidy Zinger

J Autoimmun· August 2009

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B-cell activating factor (BAFF) plays a role in the mechanism of action of a tolerogenic peptide that ameliorates lupus.
Reshmi Parameswaran, Hava Ben David, Amir Sharabi, Heidy Zinger, Edna Mozes

Clin Immunol· May 2009

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The tolerogenic peptide hCDR1 downregulates pathogenic cytokines and apoptosis and upregulates immunosuppressive molecules and regulatory T cells in peripheral blood mononuclear cells of lupus patients.
Zev M Sthoeger, Amir Sharabi, Molly Dayan, Heidy Zinger, Ilan Asher

Hum Immunol· March 2009

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Altered gene expression in mice with lupus treated with edratide, a peptide that ameliorates the disease manifestations.
Anat Elmann, Amir Sharabi, Molly Dayan, Heidy Zinger, Ron Ophir

Arthritis Rheum· July 2007

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A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+CD25+ cells and TGF-beta.
Amir Sharabi, Heidy Zinger, Maya Zborowsky, Zev M Sthoeger, Edna Mozes

Proc Natl Acad Sci U S A· June 2006

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IL-1 beta-deficient mice are resistant to induction of experimental SLE.
Elena Voronov, Molly Dayan, Heidy Zinger, Lubov Gayvoronsky, Jian-Ping Lin

Eur Cytokine Netw· June 2006

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Amelioration of murine lupus by a peptide, based on the complementarity determining region-1 of an autoantibody as compared to dexamethasone: different effects on cytokines and apoptosis.
Amir Sharabi, Asher Haviv, Heidy Zinger, Molly Dayan, Edna Mozes

Clin Immunol· May 2006

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Amelioration of SLE-like manifestations in (NZBxNZW)F1 mice following treatment with a peptide based on the complementarity determining region 1 of an autoantibody is associated with a down-regulation of apoptosis and of the pro-apoptotic factor JNK kinase.
Micha J Rapoport, Amir Sharabi, Dorit Aharoni, Olga Bloch, Heidy Zinger

Clin Immunol· December 2005

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The inhibition of autoreactive T cell functions by a peptide based on the CDR1 of an anti-DNA autoantibody is via TGF-beta-mediated suppression of LFA-1 and CD44 expression and function.
Uri Sela, Nora Mauermann, Rami Hershkoviz, Heidy Zinger, Molly Dayan

J Immunol· December 2005

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A peptide based on the complementarity determining region 1 of a human monoclonal autoantibody ameliorates spontaneous and induced lupus manifestations in correlation with cytokine immunomodulation.
Dror Luger, Molly Dayan, Heidy Zinger, Jian-Ping Liu, Edna Mozes

J Clin Immunol· November 2004

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The effect of IL-12 on clinical and laboratory aspects of experimental SLE in young and aging mice.
Rephael Segal, Molly Dayan, Heidy Zinger, Beno Habut, Gene M Shearer

Exp Gerontol· June 2003

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Lupus manifestations in severe combined immunodeficient (SCID) mice and in human/mouse radiation chimeras.
Zev Sthoeger, Heidy Zinger, Benny Dekel, Fabian Arditi, Yair Reisner

J Clin Immunol· March 2003

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Peptides based on the complementarity-determining regions of a pathogenic autoantibody mitigate lupus manifestations of (NZB x NZW)F1 mice via active suppression.
Heidy Zinger, Eran Eilat, Asher Meshorer, Edna Mozes

Int Immunol· February 2003

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A peptide based on an anti-DNA autoantibody downregulates matrix metalloproteinases in murine models of lupus.
Anat Faber-Elmann, Eran Eilat, Heidy Zinger, Edna Mozes

Clin Immunol· November 2002

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Treatment of induced murine SLE with a peptide based on the CDR3 of an anti-DNA antibody reverses the pattern of pathogenic cytokines.
Naama Brosh, Heidy Zinger, Edna Mozes

Autoimmunity· May 2002

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