Publications by authors named "Heiko Niessen"

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Initiation of a global consortium to study the progression of age-related macular degeneration: RIMR AMD consortium report # 1.
Srinivas R Sadda, Charles C Wykoff, Itay Chowers, Jean-Francois Korobelnik, Raja Narayana, Heiko G Niessen

Graefes Arch Clin Exp Ophthalmol· December 2025

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Longitudinal Cerebral Structural, Microstructural, and Functional Alterations After Brain Tumor Surgery for Early Detection of Recurrent Tumors.
Rebecca Kassubek, Mario Amend, Heiko Niessen, Bernd Schmitz, Jens Engelke

Biomedicines· November 2025

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Comprehensive biomarker and modeling approach to support dose finding for BI 836880, a VEGF/Ang-2 inhibitor.
Sascha Keller, Ulrich Kunz, Ulrike Schmid, Jack Beusmans, Martin Büchert, Heiko G Niessen

J Transl Med· October 2024

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Tryptophan catabolites and depression in the general population: results from the Gutenberg Health Study.
Matthias Michal, Andreas Schulz, Philipp S Wild, Thomas Koeck, Thomas Münzel, Heiko G Niessen

BMC Psychiatry· January 2023

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The Combination of MR Elastography and Proton Density Fat Fraction Improves Diagnosis of Nonalcoholic Steatohepatitis.
Salem Alsaqal, Paul Hockings, Håkan Ahlström, Anders Gummesson, Anders Hedström, Heiko G Niessen

J Magn Reson Imaging· August 2022

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Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans.
Fredrik Rosqvist, Michael Fridén, Johan Vessby, Paul Hockings, Johannes Hulthe, Heiko G Niessen

Clin Nutr· April 2022

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Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease.
Michael Fridén, Fredrik Rosqvist, Håkan Ahlström, Heiko G Niessen, Christian Schultheis

Front Med (Lausanne)· January 2022

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The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation.
Yuri Milaneschi, Kelly A Allers, Aartjan T F Beekman, Erik J Giltay, Sascha Keller, Heiko G Niessen

Brain Behav Immun· October 2021

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Design and rationale of the EMPA-VISION trial: investigating the metabolic effects of empagliflozin in patients with heart failure.
Moritz J Hundertmark, Olorunsola F Agbaje, Ruth Coleman, Jyothis T George, Rolf Grempler, Heiko G Niessen

ESC Heart Fail· August 2021

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Advanced magnetic resonance imaging to support clinical drug development for malignant glioma.
Rebecca Kassubek, Hans-Peter Müller, Andrea Thiele, Jan Kassubek, Heiko G Niessen

Drug Discov Today· February 2021

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Challenges in IBD Research: Novel Technologies.
Manish Dhyani, Nitin Joshi, Willem A Bemelman, Michael S Gee, Vijay Yajnik, Heiko G Niessen

Inflamm Bowel Dis· May 2019

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Ventral Striatal D2/3 Receptor Availability Is Associated with Impulsive Choice Behavior As Well As Limbic Corticostriatal Connectivity.
Rebecca L Barlow, Martin Gorges, Alfie Wearn, Heiko G Niessen, Jan Kassubek

Int J Neuropsychopharmacol· July 2018

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Animal models for the study of inflammatory bowel diseases: a meta-analysis on modalities for imaging inflammatory lesions.
Sveva Auletta, Rita Bonfiglio, Andreas Wunder, Michela Varani, Filippo Galli, Heiko G Niessen

Q J Nucl Med Mol Imaging· March 2018

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Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis: Integrated Quantification of Plaque Inflammation, Permeability, and Burden During Treatment With a Leukotriene A4 Hydrolase Inhibitor.
Claudia Calcagno, Olivier Lairez, Julie Hawkins, Steven W Kerr, Melanie S Dugas, Heiko G Niessen

JACC Cardiovasc Imaging· February 2018

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Clinical imaging in anti-atherosclerosis drug development.
Alexander Ehlgen, Anders Bylock, Jörg Kreuzer, Michael Koslowski, Florian Gantner, Heiko G Niessen

Drug Discov Today· November 2015

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A comparative PET imaging study with the reversible and irreversible EGFR tyrosine kinase inhibitors [(11)C]erlotinib and [(18)F]afatinib in lung cancer-bearing mice.
Paul Slobbe, Albert D Windhorst, Marijke Stigter-van Walsum, Egbert F Smit, Heiko G Niessen

EJNMMI Res· April 2015

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Development of [18F]afatinib as new TKI-PET tracer for EGFR positive tumors.
Paul Slobbe, Albert D Windhorst, Marijke Stigter-van Walsum, Robert C Schuit, Egbert F Smit, Heiko G Niessen

Nucl Med Biol· October 2014

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MRI allows for longitudinal quantitative analysis of body fat composition in rats: an analysis of sibutramine-associated changes at the group level.
Hans-Peter Müller, Heiko G Niessen, Thomas Kaulisch, Albert C Ludolph, Jan Kassubek

Magn Reson Imaging· September 2013

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Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity.
Matthias Kern, Nora Klöting, Heiko G Niessen, Leo Thomas, Detlef Stiller

PLoS One· March 2013

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A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons.
Kerstin E Braunstein, Judith Eschbach, Krisztina Ròna-Vörös, Rana Soylu, Elli Mikrouli, Heiko G Niessen

Hum Mol Genet· November 2010

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Guidelines for preclinical animal research in ALS/MND: A consensus meeting.
Albert C Ludolph, Caterina Bendotti, Eran Blaugrund, Adriano Chio, Linda Greensmith, Heiko G Niessen

Amyotroph Lateral Scler· August 2010

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Inductively coupled Helmholtz coil on a dedicated imaging platform for the in vivo 1H-MRS measurement of intramyocellular lipids in the hind leg of rats.
Michael Neumaier, Heiko G Niessen, Thomas Kaulisch, Detlef Stiller

Magn Reson Med· October 2009

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Subfield-specific loss of hippocampal N-acetyl aspartate in temporal lobe epilepsy.
Stefan Vielhaber, Heiko G Niessen, Grazyna Debska-Vielhaber, Alexei P Kudin, Jörg Wellmer

Epilepsia· January 2008

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Frequency-dependent activation pattern in the rat hippocampus, a simultaneous electrophysiological and fMRI study.
Frank Angenstein, Elena Kammerer, Heiko G Niessen, Julietta U Frey, Henning Scheich

Neuroimage· October 2007

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Vacuolization correlates with spin-spin relaxation time in motor brainstem nuclei and behavioural tests in the transgenic G93A-SOD1 mouse model of ALS.
Selina Bucher, Kerstin E Braunstein, Heiko G Niessen, Thomas Kaulisch, Michael Neumaier

Eur J Neurosci· October 2007

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