Publications by authors named "Heiman Chow"

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Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5.
Zhefan Stephen Chen, Shaohong Isaac Peng, Lok I Leong, Terence Gall-Duncan, Nathan Siu Jun Wong, Hei-Man Chow

Nat Commun· April 2025

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The mitochondrial long non-coding RNA lncMtloop regulates mitochondrial transcription and suppresses Alzheimer's disease.
Wandi Xiong, Kaiyu Xu, Jacquelyne Ka-Li Sun, Siling Liu, Baizhen Zhao, Hei-Man Chow

EMBO J· December 2024

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Force-induced tail-autotomy mitochondrial fission and biogenesis of matrix-excluded mitochondrial-derived vesicles for quality control.
Xiaoying Liu, Linyu Xu, Yutong Song, Zhihao Zhao, Xinyu Li, Hei-Man Chow

Proc Natl Acad Sci U S A· April 2024

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A critical review of ethanol effects on neuronal firing: A metabolic perspective.
Dina Popova, Jacquelyne Sun, Hei-Man Chow, Ronald P Hart

Alcohol Clin Exp Res (Hoboken)· March 2024

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Clinical characteristics of unvaccinated or incompletely vaccinated children with neurological manifestations due to SARS-CoV-2 Omicron infection.
Winnie Wan-Yee Tso, Mike Yat-Wah Kwan, Janette Siu-Yin Kwok, Jessica Oi-Ling Tsang, Cyril Chik-Yan Yip, Mathew Siu-Chun Chow, Chin-Ying Chow, Hei-Man Chow

J Med Virol· July 2023

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Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons.
Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Hei-Man Chow

Aging Cell· February 2023

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Insulin stimulates atypical protein kinase C-mediated phosphorylation of the neuronal adaptor FE65 to potentiate neurite outgrowth by activating ARF6-Rac1 signaling.
Dennis Dik-Long Chau, Wen Li, Wai Wa Ray Chan, Jacquelyne Ka-Li Sun, Yuqi Zhai, Hei-Man Chow

FASEB J· November 2022

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Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance.
Lige Leng, Ziqi Yuan, Ruiyuan Pan, Xiao Su, Han Wang, Hei-Man Chow

Nat Metab· October 2022

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Author Correction: Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance.
Lige Leng, Ziqi Yuan, Ruiyuan Pan, Xiao Su, Han Wang, Hei-Man Chow

Nat Metab· October 2022

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A peptide inhibitor that rescues polyglutamine-induced synaptic defects and cell death through suppressing RNA and protein toxicities.
Shaohong Isaac Peng, Lok I Leong, Jacquelyne Ka-Li Sun, Zhefan Stephen Chen, Hei-Man Chow

Mol Ther Nucleic Acids· September 2022

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Cytosolic delivery of CDK4/6 inhibitor p16 protein using engineered protein crystals for cancer therapy.
Zaofeng Yang, Meigui Yang, Hei-Man Chow, Suk Ying Tsang, Marianne M Lee

Acta Biomater· November 2021

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ATM loss disrupts the autophagy-lysosomal pathway.
Aifang Cheng, Kai-Hei Tse, Hei-Man Chow, Yunqiao Gan, Xuan Song

Autophagy· August 2021

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Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes.
Hei-Man Chow, Jacquelyne Ka-Li Sun, Ronald P Hart, Kenneth King-Yip Cheng, Clara H L Hung

Adv Sci (Weinh)· August 2021

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CAG RNAs induce DNA damage and apoptosis by silencing expression in polyglutamine degeneration.
Shaohong Peng, Pei Guo, Xiao Lin, Ying An, Kong Hung Sze, Hei-Man Chow

Proc Natl Acad Sci U S A· May 2021

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Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease.
Ying Zhang, Zhongyu Zhang, Lianwei Li, Kaiyu Xu, Zhanshan Ma, Hei-Man Chow

FASEB J· December 2020

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Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover.
Jiechao Zhou, Hei-Man Chow, Yan Liu, Di Wu, Meng Shi

Biol Psychiatry· April 2020

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Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence.
Hei-Man Chow, Meng Shi, Aifang Cheng, Yuehong Gao, Guimiao Chen

Nat Neurosci· November 2019

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ATM is activated by ATP depletion and modulates mitochondrial function through NRF1.
Hei-Man Chow, Aifang Cheng, Xuan Song, Mavis R Swerdel, Ronald P Hart

J Cell Biol· March 2019

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ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.
Aifang Cheng, Teng Zhao, Kai-Hei Tse, Hei-Man Chow, Yong Cui

Proc Natl Acad Sci U S A· January 2018

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Loopholes in the DNA contract kill neurons.
Karl Herrup, Kai-Hei Tse, Hei-Man Chow

Nat Neurosci· August 2017

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Erratum to: The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.
Jianmin Chen, Yanping Chen, Graham Vail, Heiman Chow, Yang Zhang

Mol Neurodegener· January 2017

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The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.
Jianmin Chen, Yanping Chen, Graham Vail, Heiman Chow, Yang Zhang

Mol Neurodegener· August 2016

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Genomic integrity and the ageing brain.
Hei-man Chow, Karl Herrup

Nat Rev Neurosci· November 2015

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CDK5 activator protein p25 preferentially binds and activates GSK3β.
Hei-Man Chow, Dong Guo, Jie-Chao Zhou, Guan-Yun Zhang, Hui-Fang Li

Proc Natl Acad Sci U S A· November 2014

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