Publications by authors named "Hein Schepers"

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Opt1 imports CoA precursors as glutathione mixed disulfides.
Jouke Jan Wedman, Lotte de Vries, Bart van Lingen, Marianne van der Zwaag, Rubén Gómez-Sánchez, Hein Schepers

J Biol Chem· September 2025

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Coenzyme A precursors flow from mother to zygote and from microbiome to host.
Yi Yu, Marianne van der Zwaag, Jouke Jan Wedman, Hjalmar Permentier, Niels Plomp, Hein Schepers

Mol Cell· July 2022

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Targeting DNA topoisomerases or checkpoint kinases results in an overload of chaperone systems, triggering aggregation of a metastable subproteome.
Wouter Huiting, Suzanne L Dekker, Joris C J van der Lienden, Rafaella Mergener, Maiara K Musskopf, Hein Schepers

Elife· February 2022

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The Hippo signaling pathway effector YAP promotes salivary gland regeneration after injury.
Cecilia Rocchi, Davide Cinat, Paola Serrano Martinez, Anne L Jellema-de Bruin, Mirjam Baanstra, Hein Schepers

Sci Signal· December 2021

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Coenzyme A levels influence protein acetylation, CoAlation and 4'-phosphopantetheinylation: Expanding the impact of a metabolic nexus molecule.
Yi Yu, Isabele Fattori Moretti, Nicola A Grzeschik, Ody C M Sibon, Hein Schepers

Biochim Biophys Acta Mol Cell Res· April 2021

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Vps13 is required for timely removal of nurse cell corpses.
Anita I E Faber, Marianne van der Zwaag, Hein Schepers, Ellie Eggens-Meijer, Bart Kanon

Development· October 2020

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Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle.
Yingying Cong, Mustafa Ulasli, Hein Schepers, Mario Mauthe, Philip V'kovski

J Virol· January 2020

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Differential redox-regulation and mitochondrial dynamics in normal and leukemic hematopoietic stem cells: A potential window for leukemia therapy.
Katharina Mattes, Edo Vellenga, Hein Schepers

Crit Rev Oncol Hematol· December 2019

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CoA-dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases.
Roald A Lambrechts, Hein Schepers, Yi Yu, Marianne van der Zwaag, Kaija J Autio

EMBO Mol Med· December 2019

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Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern.
Gerbrig Berger, Mylene Gerritsen, Guoqiang Yi, Theresia N Koorenhof-Scheele, Leonie I Kroeze, Hein Schepers

Blood Adv· October 2019

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Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells.
Katharina Mattes, Marjan Geugien, Patrick M Korthuis, Annet Z Brouwers-Vos, Rudolf S N Fehrmann, Hein Schepers

Exp Hematol· May 2019

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CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions.
Johannes Jung, Sonja C Buisman, Ellen Weersing, Albertina Dethmers-Ausema, Erik Zwart, Hein Schepers

Cell Rep· February 2019

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Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT.
Gerbrig Berger, Leonie I Kroeze, Theresia N Koorenhof-Scheele, Aniek O de Graaf, Kenichi Yoshida, Hein Schepers

Blood· April 2018

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CITED2 affects leukemic cell survival by interfering with p53 activation.
Katharina Mattes, Gerbrig Berger, Marjan Geugien, Edo Vellenga, Hein Schepers

Cell Death Dis· October 2017

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Impact of genetic variation in the SMIM1 gene on Vel expression levels.
Lonneke Haer-Wigman, Tamara C Stegmann, Shabnam Solati, Aïcha Ait Soussan, Erik Beckers, Hein Schepers

Transfusion· June 2015

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Ex vivo assays to study self-renewal, long-term expansion, and leukemic transformation of genetically modified human hematopoietic and patient-derived leukemic stem cells.
Pallavi Sontakke, Marco Carretta, Marta Capala, Hein Schepers, Jan Jacob Schuringa

Methods Mol Biol· March 2015

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The TAK1-NF-κB axis as therapeutic target for AML.
Matthieu Cornelis Johannes Bosman, Hein Schepers, Jennifer Jaques, Annet Zwaantien Brouwers-Vos, Wim Johannes Quax

Blood· November 2014

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SMIM1 underlies the Vel blood group and influences red blood cell traits.
Ana Cvejic, Lonneke Haer-Wigman, Jonathan C Stephens, Myrto Kostadima, Peter A Smethurst, Hein Schepers

Nat Genet· May 2013

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Seventy-five genetic loci influencing the human red blood cell.
Pim van der Harst, Weihua Zhang, Irene Mateo Leach, Augusto Rendon, Niek Verweij, Hein Schepers

Nature· December 2012

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STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells.
Hein Schepers, Albertus T J Wierenga, Edo Vellenga, Jan Jacob Schuringa

JAKSTAT· January 2012

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Cited2 is an essential regulator of adult hematopoietic stem cells.
Kamil R Kranc, Hein Schepers, Neil P Rodrigues, Simon Bamforth, Ellen Villadsen

Cell Stem Cell· December 2009

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Induced pluripotent stem cells: will they be safe?
Mathilde Jalving, Hein Schepers

Curr Opin Mol Ther· August 2009

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Ex vivo assays to study self-renewal and long-term expansion of genetically modified primary human acute myeloid leukemia stem cells.
Jan Jacob Schuringa, Hein Schepers

Methods Mol Biol· May 2009

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Mucin1 expression is enriched in the human stem cell fraction of cord blood and is upregulated in majority of the AML cases.
Szabolcs Fatrai, Hein Schepers, Henko Tadema, Edo Vellenga, Simon M G J Daenen

Exp Hematol· October 2008

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Establishing long-term cultures with self-renewing acute myeloid leukemia stem/progenitor cells.
Djoke van Gosliga, Hein Schepers, Aleksandra Rizo, Dorina van der Kolk, Edo Vellenga

Exp Hematol· October 2007

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