Publications by authors named "Heinrich Roder"

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Direct comparison of the structural dynamics between spontaneous and ligand-induced folding of staphylococcal nuclease.
Yujiro Mori, Takuya Mizukami, Issei Suzuki, Shingo Fukazawa, Kosuke Miki, Heinrich Roder

Protein Sci· May 2025

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Development and validation of a serum proteomic test for predicting patient outcomes in advanced non-small cell lung cancer treated with atezolizumab or docetaxel.
Minu K Srivastava, Wei Zou, Mark McCleland, Joanna Roder, Senait Asmellash, Heinrich Roder

J Immunother Cancer· May 2025

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Molecular and translational biology of the blood-based VeriStrat® proteomic test used in cancer immunotherapy treatment guidance.
Matthew A Koc, Timothy Aaron Wiles, Daniel C Weinhold, Steven Rightmyer, Amanda L Weaver, Joanna Roder, Heinrich Roder

J Mass Spectrom Adv Clin Lab· November 2023

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Folding of Staphylococcal Nuclease Induced by Binding of Chemically Modified Substrate Analogues Sheds Light on Mechanisms of Coupled Folding/Binding Reactions.
Yujiro Mori, Takuya Mizukami, Saho Segawa, Heinrich Roder, Kosuke Maki

Biochemistry· June 2023

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PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation.
Jie Zhang, Yijun Yang, Xinhua Li, Gen Li, Takuya Mizukami, Heinrich Roder

Cell Death Differ· May 2023

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Advances in Mixer Design and Detection Methods for Kinetics Studies of Macromolecular Folding and Binding on the Microsecond Time Scale.
Takuya Mizukami, Heinrich Roder

Molecules· May 2022

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Effects of ionic strength on the folding and stability of SAMP1, a ubiquitin-like halophilic protein.
Takuya Mizukami, John T Bedford, ShanHui Liao, Lesley H Greene, Heinrich Roder

Biophys J· February 2022

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Semi-Quantitative MALDI Measurements of Blood-Based Samples for Molecular Diagnostics.
Matthew A Koc, Senait Asmellash, Patrick Norman, Steven Rightmyer, Joanna Roder, Heinrich Roder

Molecules· February 2022

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Predicting prognosis in COVID-19 patients using machine learning and readily available clinical data.
Thomas W Campbell, Melissa P Wilson, Heinrich Roder, Samantha MaWhinney, Robert W Georgantas, Joanna Roder

Int J Med Inform· November 2021

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Explaining multivariate molecular diagnostic tests via Shapley values.
Joanna Roder, Laura Maguire, Robert Georgantas, Heinrich Roder

BMC Med Inform Decis Mak· July 2021

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Detection of Hepatocellular Carcinoma in a High-Risk Population by a Mass Spectrometry-Based Test.
Devalingam Mahalingam, Leonidas Chelis, Imran Nizamuddin, Sunyoung S Lee, Stylianos Kakolyris, Heinrich Roder, Joanna Roder

Cancers (Basel)· June 2021

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A Phase 2 Randomized Placebo-Controlled Adjuvant Trial of GI-4000, a Recombinant Yeast Expressing Mutated RAS Proteins in Patients with Resected Pancreas Cancer.
Peter Muscarella, Tanios Bekaii-Saab, Kristi McIntyre, Alexander Rosemurgy, Sharona B Ross, Heinrich Roder, Joanna Roder

J Pancreat Cancer· March 2021

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A proposal for score assignment to characterize biological processes from mass spectral analysis of serum.
Joanna Roder, Lelia Net, Carlos Oliveira, Krista Meyer, Senait Asmellash, Heinrich Roder

Clin Mass Spectrom· November 2020

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A Serum Protein Classifier Identifying Patients with Advanced Non-Small Cell Lung Cancer Who Derive Clinical Benefit from Treatment with Immune Checkpoint Inhibitors.
Mirte Muller, Karlijn Hummelink, Daan P Hurkmans, Anna-Larissa N Niemeijer, Kim Monkhorst, Joanna Roder, Heinrich Roder

Clin Cancer Res· October 2020

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Definition and Independent Validation of a Proteomic-Classifier in Ovarian Cancer.
Sabine Kasimir-Bauer, Joanna Roder, Eva Obermayr, Sven Mahner, Ignace Vergote, Heinrich Roder

Cancers (Basel)· September 2020

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Energetics and kinetics of substrate analog-coupled staphylococcal nuclease folding revealed by a statistical mechanical approach.
Takuya Mizukami, Shunta Furuzawa, Satoru G Itoh, Saho Segawa, Teikichi Ikura, Heinrich Roder

Proc Natl Acad Sci U S A· August 2020

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Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones.
Makiko Iwafuchi, Isabel Cuesta, Greg Donahue, Naomi Takenaka, Anna B Osipovich, Heinrich Roder

Nat Genet· April 2020

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Extending the information content of the MALDI analysis of biological fluids via multi-million shot analysis.
Maxim Tsypin, Senait Asmellash, Krista Meyer, Brandon Touchet, Heinrich Roder

PLoS One· March 2020

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Mass Spectrometry-Based Multivariate Proteomic Tests for Prediction of Outcomes on Immune Checkpoint Blockade Therapy: The Modern Analytical Approach.
Julia Grigorieva, Senait Asmellash, Lelia Net, Maxim Tsypin, Heinrich Roder, Joanna Roder

Int J Mol Sci· January 2020

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A dropout-regularized classifier development approach optimized for precision medicine test discovery from omics data.
Joanna Roder, Carlos Oliveira, Lelia Net, Maxim Tsypin, Benjamin Linstid, Heinrich Roder

BMC Bioinformatics· June 2019

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Robust identification of molecular phenotypes using semi-supervised learning.
Heinrich Roder, Carlos Oliveira, Lelia Net, Benjamin Linstid, Maxim Tsypin, Joanna Roder

BMC Bioinformatics· May 2019

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Conformational Changes in the Cytoplasmic Region of KIR3DL1 upon Interaction with SHP-2.
Hong Cheng, Vered Schwell, Brett R Curtis, Ruzaliya Fazlieva, Heinrich Roder

Structure· April 2019

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Proteomic test for anti-PD-1 checkpoint blockade treatment of metastatic melanoma with and without BRAF mutations.
Paolo A Ascierto, Mariaelena Capone, Antonio M Grimaldi, Domenico Mallardo, Ester Simeone, Heinrich Roder, Joanna Roder

J Immunother Cancer· March 2019

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Isothermal Analysis of ThermoFluor Data can readily provide Quantitative Binding Affinities.
Nan Bai, Heinrich Roder, Alex Dickson, John Karanicolas

Sci Rep· February 2019

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Complex Folding Landscape of Apomyoglobin at Acidic pH Revealed by Ultrafast Kinetic Analysis of Core Mutants.
Takuya Mizukami, Ming Xu, Ruzaliya Fazlieva, Valentina E Bychkova, Heinrich Roder

J Phys Chem B· December 2018

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