Publications by authors named "Helen C Hope"

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Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure.
Helen Carrasco Hope, Jana de Sostoa, Pierpaolo Ginefra, Massimo Andreatta, Yi-Hsuan Chiang

Nat Cancer· September 2025

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The immunometabolic roots of aging.
Pierpaolo Ginefra, Helen C Hope, Girieca Lorusso, Patrizia D'Amelio, Nicola Vannini

Curr Opin Immunol· December 2024

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Urolithin-A Promotes CD8+ T Cell-mediated Cancer Immunosurveillance via FOXO1 Activation.
Pierpaolo Ginefra, Helen Carrasco Hope, Yi-Hsuan Chiang, Sophie Nutten, Stephanie Blum

Cancer Res Commun· May 2024

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PGE inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function.
Matteo Morotti, Alizee J Grimm, Helen Carrasco Hope, Marion Arnaud, Mathieu Desbuisson

Nature· May 2024

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Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems.
Mukul Girotra, Yi-Hsuan Chiang, Melanie Charmoy, Pierpaolo Ginefra, Helen Carrasco Hope

Nat Aging· September 2023

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TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8 T cells.
Helen Carrasco Hope, Gabriella Pickersgill, Pierpaolo Ginefra, Nicola Vannini, Graham P Cook

Front Immunol· August 2022

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The Role of Non-essential Amino Acids in T Cell Function and Anti-tumour Immunity.
Helen Carrasco Hope, Robert J Salmond

Arch Immunol Ther Exp (Warsz)· October 2021

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Coordination of asparagine uptake and asparagine synthetase expression modulates CD8+ T cell activation.
Helen Carrasco Hope, Rebecca J Brownlie, Christopher M Fife, Lynette Steele, Mihaela Lorger

JCI Insight· May 2021

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Targeting the tumor microenvironment and T cell metabolism for effective cancer immunotherapy.
Helen Carrasco Hope, Robert J Salmond

Eur J Immunol· August 2019

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