Publications by authors named "Helen Christian"

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Systems Biology and Functional Assessments of Human iPSC-Cardiomyocyte Models of Insulin Resistance Capture Key Hallmarks of Diabetic Cardiomyopathy.
Ryan D Carter, Ujang Purnama, Marcos Castro-Guarda, Claudia N Montes-Aparicio, Anandhakumar Chandran, Helen C Christian

Diabetes· November 2025

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Paracrine FGF1 signaling directs pituitary architecture and size.
Konstantin Khetchoumian, Kevin Sochodolsky, Chrystel Lafont, Arthur Gouhier, Amandine Bemmo, Helen Christian

Proc Natl Acad Sci U S A· October 2024

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Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel.
Helen E Chmura, Cassandra Duncan, Ben Saer, Jeanette T Moore, Brian M Barnes, Helen C Christian

Commun Biol· May 2022

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Hyperprolactinemia in a male pituitary androgen receptor knockout mouse is associated with female-like lactotroph development.
Laura O'Hara, Helen C Christian, Paul Le Tissier, Lee B Smith

Andrology· September 2021

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Characterisation of a mural cell network in the murine pituitary gland.
Laura O'Hara, Helen C Christian, Nathan Jeffery, Paul Le Tissier, Lee B Smith

J Neuroendocrinol· October 2020

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Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2.
Konstantin Khetchoumian, Aurélio Balsalobre, Alexandre Mayran, Helen Christian, Valérie Chénard

Nat Commun· September 2019

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S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation.
Yi Athena Ren, Teresa Monkkonen, Michael T Lewis, Daniel J Bernard, Helen C Christian

JCI Insight· July 2019

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Disentangling juxtacrine from paracrine signalling in dynamic tissue.
Hiroshi Momiji, Kirsty L Hassall, Karen Featherstone, Anne V McNamara, Amanda L Patist, Helen C Christian

PLoS Comput Biol· June 2019

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Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration.
Anna Hoerder-Suabedissen, Kim V Korrell, Shuichi Hayashi, Alexander Jeans, Denise M O Ramirez, Helen C Christian

Cereb Cortex· May 2019

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Phenotypic dissection of the mouse knockout by complementation with human renin.
Charlotte Buckley, Robert J Nelson, Linda J Mullins, Matthew G F Sharp, Stewart Fleming, Helen Christian

J Biol Chem· January 2018

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Zebrafish mesonephric renin cells are functionally conserved and comprise two distinct morphological populations.
Sebastien A Rider, Helen C Christian, Linda J Mullins, Amelia R Howarth, Calum A MacRae

Am J Physiol Renal Physiol· April 2017

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Unacylated ghrelin promotes adipogenesis in rodent bone marrow via ghrelin O-acyl transferase and GHS-R activity: evidence for target cell-induced acylation.
Anna L Hopkins, Timothy A S Nelson, Irina A Guschina, Lydia C Parsons, Charlotte L Lewis, Helen C Christian

Sci Rep· March 2017

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High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart.
Daniel Aston, Rebecca A Capel, Kerrie L Ford, Helen C Christian, Gary R Mirams

Sci Rep· January 2017

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Human kidney pericytes produce renin.
Ania Stefanska, Christopher Kenyon, Helen C Christian, Charlotte Buckley, Isaac Shaw

Kidney Int· December 2016

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Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca Signals.
Pulak Kar, Gary R Mirams, Helen C Christian, Anant B Parekh

Mol Cell· November 2016

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An essential cell-autonomous role for hepcidin in cardiac iron homeostasis.
Samira Lakhal-Littleton, Magda Wolna, Yu Jin Chung, Helen C Christian, Lisa C Heather

Elife· November 2016

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Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation.
Peter Gergics, Helen C Christian, Monica S Choo, Adnan Ajmal, Sally A Camper

Endocrinology· September 2016

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C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Ruxandra Dafinca, Jakub Scaber, Nida'a Ababneh, Tatjana Lalic, Gregory Weir, Helen Christian

Stem Cells· August 2016

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ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.
Hugo J R Fernandes, Elizabeth M Hartfield, Helen C Christian, Evangelia Emmanoulidou, Ying Zheng

Stem Cell Reports· March 2016

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Spatially coordinated dynamic gene transcription in living pituitary tissue.
Karen Featherstone, Kirsty Hey, Hiroshi Momiji, Anne V McNamara, Amanda L Patist, Helen C Christian

Elife· February 2016

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Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals.
Shona H Wood, Helen C Christian, Katarzyna Miedzinska, Ben R C Saer, Mark Johnson

Curr Biol· October 2015

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Oocyte glycoproteins regulate the form and function of the follicle basal lamina and theca cells.
Alice P Christensen, Saloni H Patel, Patricia Grasa, Helen C Christian, Suzannah A Williams

Dev Biol· May 2015

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Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.
Pamela V Lear, David González-Touceda, Begoña Porteiro Couto, Patricia Viaño, Vanessa Guymer, Helen C Christian

Endocrinology· March 2015

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Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function.
Samira Lakhal-Littleton, Magda Wolna, Carolyn A Carr, Jack J J Miller, Helen C Christian

Proc Natl Acad Sci U S A· March 2015

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The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia.
Mary E Slingo, Philip J Turner, Helen C Christian, Keith J Buckler, Peter A Robbins

J Appl Physiol (1985)· April 2014

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