Publications by authors named "Helen L Fitzsimons"

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N-terminal oligomerization drives HDAC4 nuclear condensation and neurodevelopmental dysfunction in .
Hannah R Hawley, Andrew J Sutherland-Smith, Matthew S Savoian, Helen L Fitzsimons

Open Biol· October 2025

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A novel three-dimensional model of infantile haemangioma.
Raka Mitra, Tracy K Hale, Helen L Fitzsimons, Clint Gray, Madeleine P J White

Br J Dermatol· April 2025

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Recent advances in understanding the molecular basis of infantile haemangioma development.
Raka Mitra, Helen L Fitzsimons, Tracy Hale, Swee T Tan, Clint Gray

Br J Dermatol· October 2024

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Deciphering the roles of subcellular distribution and interactions involving the MEF2 binding region, the ankyrin repeat binding motif and the catalytic site of HDAC4 in Drosophila neuronal morphogenesis.
Wei Jun Tan, Hannah R Hawley, Sarah J Wilson, Helen L Fitzsimons

BMC Biol· January 2024

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Comparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in .
Hannah R Hawley, Celestine J Roberts, Helen L Fitzsimons

MicroPubl Biol· June 2023

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Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila.
Silvia Schwartz, Sarah J Wilson, Tracy K Hale, Helen L Fitzsimons

Mol Brain· May 2023

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Herzog is not required for mushroom body development or courtship learning & memory but is required for eye development in .
Madeleine J Palmer, Helen L Fitzsimons

MicroPubl Biol· January 2023

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Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration.
Angelia J Hura, Hannah R Hawley, Wei Jun Tan, Rebecca J Penny, Jessie C Jacobsen, Helen L Fitzsimons

Mol Brain· February 2022

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Increased Abundance of Nuclear HDAC4 Impairs Neuronal Development and Long-Term Memory.
Patrick Main, Wei Jun Tan, David Wheeler, Helen L Fitzsimons

Front Mol Neurosci· March 2021

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The ERM protein Moesin is essential for neuronal morphogenesis and long-term memory in Drosophila.
Patrick S Freymuth, Helen L Fitzsimons

Mol Brain· August 2017

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SymB and SymC, two membrane associated proteins, are required for Epichloë festucae hyphal cell-cell fusion and maintenance of a mutualistic interaction with Lolium perenne.
Kimberly A Green, Yvonne Becker, Aiko Tanaka, Daigo Takemoto, Helen L Fitzsimons

Mol Microbiol· February 2017

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An Epichloë festucae homologue of MOB3, a component of the STRIPAK complex, is required for the establishment of a mutualistic symbiotic interaction with Lolium perenne.
Kimberly A Green, Yvonne Becker, Helen L Fitzsimons, Barry Scott

Mol Plant Pathol· December 2016

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Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9.
Silvia Schwartz, Mauro Truglio, Maxwell J Scott, Helen L Fitzsimons

Genetics· July 2016

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Towards next generation maggot debridement therapy: transgenic Lucilia sericata larvae that produce and secrete a human growth factor.
Rebecca J Linger, Esther J Belikoff, Ying Yan, Fang Li, Holly A Wantuch, Helen L Fitzsimons

BMC Biotechnol· March 2016

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The Class IIa histone deacetylase HDAC4 and neuronal function: Nuclear nuisance and cytoplasmic stalwart?
Helen L Fitzsimons

Neurobiol Learn Mem· September 2015

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The histone deacetylase HDAC4 regulates long-term memory in Drosophila.
Helen L Fitzsimons, Silvia Schwartz, Fiona M Given, Maxwell J Scott

PLoS One· September 2014

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Genetic modulation of Rpd3 expression impairs long-term courtship memory in Drosophila.
Helen L Fitzsimons, Maxwell J Scott

PLoS One· August 2012

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Biodistribution and safety assessment of AAV2-GAD following intrasubthalamic injection in the rat.
Helen L Fitzsimons, Veronique Riban, Ross J Bland, Jennifer L Wendelken, Christine V Sapan

J Gene Med· April 2010

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Gene therapy in epilepsy.
Véronique Riban, Helen L Fitzsimons, Matthew J During

Epilepsia· January 2009

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HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity.
Alisha E Jung, Helen L Fitzsimons, Ross J Bland, Matthew J During, Deborah Young

Mol Ther· June 2008

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AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease.
Nicholas R Franich, Helen L Fitzsimons, Dahna M Fong, Matthias Klugmann, Matthew J During

Mol Ther· May 2008

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Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.
Michael G Kaplitt, Andrew Feigin, Chengke Tang, Helen L Fitzsimons, Paul Mattis

Lancet· June 2007

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Glucagon-like peptide-1 receptor is involved in learning and neuroprotection.
Matthew J During, Lei Cao, David S Zuzga, Jeremy S Francis, Helen L Fitzsimons

Nat Med· September 2003

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Subthalamic GAD gene therapy in a Parkinson's disease rat model.
Jia Luo, Michael G Kaplitt, Helen L Fitzsimons, David S Zuzga, Yuhong Liu

Science· October 2002

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Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain.
Helen L Fitzsimons, Ross J Bland, Matthew J During

Methods· October 2002

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