Publications by authors named "Helen May-Simera"

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BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue.
Katharina Sieckmann, Nora Winnerling, Dalila Juliana Silva Ribeiro, Seniz Yüksel, Ronja Kardinal, Helen Louise May-Simera

EMBO J· October 2025

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KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia.
Csenge K Rezi, Alina Frei, Fabiola Campestre, Karsten Boldt, Benjamin Mary, Helen L May-Simera

Curr Biol· October 2025

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Homology search confirms widespread presence of BBSome proteins in Hexapoda with implications for potential non-ciliary BBS protein functions in honey bees.
Alexander Ewerling-Haehnel, Ina Köhler, Isa Graebling, Anna Wierczeiko, Elisa Kotzurek, Helen L May-Simera

Sci Rep· October 2025

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Complement C3 Activation in the Human Retinal Pigment Epithelium.
Juliane Schikora, Antonia Nickel, Jasmin Bergert, Rike Hähnel, Aaron Dort, Helen May-Simera

Invest Ophthalmol Vis Sci· July 2025

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Loss of Bbs8 leads to cystic kidney disease in mice with reduced acetylation of ciliary alpha-tubulin through HDAC2.
Emilia Kieckhöfer, Julia Günzler, Peter A Matthiessen, Lena K Ebert, Christina Klausen, Helen May-Simera

bioRxiv· June 2025

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The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to the base of primary cilia.
Joshua Linnert, Deva Krupakar Kusuluri, Baran E Güler, Sarita Rani Patnaik, Helen Louise May-Simera

Front Cell Dev Biol· March 2025

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Role of Primary Cilia in the Eye.
Dominik Reichert, Ruchi Sharma, Helen May-Simera, Kapil Bharti

Adv Exp Med Biol· February 2025

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Structural Analysis of Cardanol and Its Biological Activities on Human Keratinocyte Cells.
Shereen Basiouni, Nina Abel, Wolfgang Eisenreich, Helen L May-Simera, Awad A Shehata

Metabolites· January 2025

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Evolutionary trajectory for nuclear functions of ciliary transport complex proteins.
Alexander Ewerling, Helen Louise May-Simera

Microbiol Mol Biol Rev· September 2024

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Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.
Viola Kretschmer, Sandra Schneider, Peter Andreas Matthiessen, Dominik Reichert, Nathan Hotaling, Helen Louise May-Simera

PLoS Biol· December 2023

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Emerging principles of primary cilia dynamics in controlling tissue organization and function.
Jay Gopalakrishnan, Kerstin Feistel, Benjamin M Friedrich, Anne Grapin-Botton, Nathalie Jurisch-Yaksi, Helen May-Simera

EMBO J· November 2023

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The actin-bundling protein Fascin-1 modulates ciliary signalling.
Lena Brücker, Stefanie Kornelia Becker, Vanessa Maissl, Gregory Harms, Maddy Parsons, Helen Louise May-Simera

J Mol Cell Biol· August 2023

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Gene augmentation of LCA5-associated Leber congenital amaurosis ameliorates bulge region defects of the photoreceptor ciliary axoneme.
Siebren Faber, Olivier Mercey, Katrin Junger, Alejandro Garanto, Helen May-Simera

JCI Insight· May 2023

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Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes.
Alexander Ewerling, Vanessa Maissl, Bill Wickstead, Helen Louise May-Simera

iScience· April 2023

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Deletion of Inhibits Metastasis Formation of Liver Cancer in -Mutant Mice.
Monserrat Gerardo-Ramírez, Vanessa Giam, Diana Becker, Marco Groth, Nils Hartmann, Helen L May-Simera

Cells· April 2023

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Anti-Inflammatory and Antioxidative Phytogenic Substances against Secret Killers in Poultry: Current Status and Prospects.
Shereen Basiouni, Guillermo Tellez-Isaias, Juan D Latorre, Brittany D Graham, Victor M Petrone-Garcia, Helen L May-Simera

Vet Sci· January 2023

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Behavioral Phenotyping of Bbs6 and Bbs8 Knockout Mice Reveals Major Alterations in Communication and Anxiety.
Nathalie Rödig, Kristin Sellmann, Malena Dos Santos Guilherme, Vu Thu Thuy Nguyen, Dirk Cleppien, Helen Louise May-Simera

Int J Mol Sci· November 2022

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Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes.
Sophia Grotz, Jessica Schäfer, Kirsten A Wunderlich, Zdenka Ellederova, Hannah Auch, Helen May-Simera

EMBO Mol Med· April 2022

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Status and Prospects of Botanical Biopesticides in Europe and Mediterranean Countries.
Fatma Acheuk, Shereen Basiouni, Awad A Shehata, Katie Dick, Haifa Hajri, Helen May-Simera

Biomolecules· February 2022

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Algae and Their Metabolites as Potential Bio-Pesticides.
Elias Asimakis, Awad A Shehata, Wolfgang Eisenreich, Fatma Acheuk, Salma Lasram, Helen May-Simera

Microorganisms· January 2022

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Primary Cilia Structure Is Prolonged in Enteric Neurons of 5xFAD Alzheimer's Disease Model Mice.
Vu Thu Thuy Nguyen, Lena Brücker, Ann-Kathrin Volz, Julia C Baumgärtner, Malena Dos Santos Guilherme, Helen May-Simera

Int J Mol Sci· December 2021

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Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles.
Ann-Kathrin Volz, Alina Frei, Viola Kretschmer, António M de Jesus Domingues, Rene F Ketting, Helen L May-Simera

Nat Commun· September 2021

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Translational readthrough of ciliopathy genes BBS2 and ALMS1 restores protein, ciliogenesis and function in patient fibroblasts.
Jonathan Eintracht, Elizabeth Forsythe, Helen May-Simera, Mariya Moosajee

EBioMedicine· August 2021

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The Interplay between Nutrition, Innate Immunity, and the Commensal Microbiota in Adaptive Intestinal Morphogenesis.
Franziska Bayer, Olga Dremova, My Phung Khuu, Könül Mammadova, Giulia Pontarollo, Helen Louise May-Simera

Nutrients· June 2021

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Loss of Ciliary Gene Results in Physiological Defects in the Retinal Pigment Epithelium.
Sandra Schneider, Rossella De Cegli, Jayapriya Nagarajan, Viola Kretschmer, Peter Andreas Matthiessen, Helen Louise May-Simera

Front Cell Dev Biol· February 2021

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