Publications by authors named "Helena Frayle"

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Predictive biomarkers for regression in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2: A prospective multicenter study in Italy.
Helena Frayle, Silvia Gori, Alessio Pagan, Marika Soldà, Cesare Romagnolo

Int J Cancer· February 2026

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Impact of differentiating between persistent and new infections on colposcopy referral in HPV-positive triage-negative women: results from the NTCC2 study.
Annarosa Del Mistro, Pamela Mancuso, Francesca Carozzi, Laura De Marco, Simonetta Bisanzi, Helena Frayle

Infect Agent Cancer· November 2025

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From infection to immortality: The role of HPV and telomerase in head and neck cancer.
Silvia Giunco, Annarosa Del Mistro, Marzia Morello, Jacopo Lidonnici, Helena Frayle

Oral Oncol· February 2025

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Extended HPV genotyping by the BD Onclarity assay: concordance with screening HPV-DNA assays, triage biomarkers, and histopathology in women from the NTCC2 study.
Laura De Marco, Simonetta Bisanzi, Guglielmo Ronco, Pamela Mancuso, Francesca Carozzi, Helena Frayle

Microbiol Spectr· January 2025

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Comparison of HPV-positive triage strategies combining extended genotyping with cytology or p16/ki67 dual staining in the Italian NTCC2 study.
Maria Benevolo, Guglielmo Ronco, Pamela Mancuso, Francesca Carozzi, Laura De Marco, Helena Frayle

EBioMedicine· June 2024

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Exploring conservative management for cervical intraepithelial neoplasia grade 2 in organised cervical cancer screening programmes: a multicentre study in Italy.
Silvia Gori, Helena Frayle, Alessio Pagan, Marika Soldà, Cesare Romagnolo

Fam Med Community Health· February 2024

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Acceptability of deferring the start of cervical cancer screening to age 30 for women vaccinated against human papillomavirus.
Gessica Martello, Silvia Gori, Helena Frayle, Silvia Franceschi, Manuel Zorzi

Prev Med Rep· December 2023

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Performance of HPV E6/E7 mRNA assay as primary screening test: Results from the NTCC2 trial.
Paolo Giorgi Rossi, Guglielmo Ronco, Pamela Mancuso, Francesca Carozzi, Elena Allia, Helena Frayle

Int J Cancer· October 2022

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p16/ki67 and E6/E7 mRNA Accuracy and Prognostic Value in Triaging HPV DNA-Positive Women.
Paolo Giorgi Rossi, Francesca Carozzi, Guglielmo Ronco, Elena Allia, Simonetta Bisanzi, Helena Frayle

J Natl Cancer Inst· March 2021

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A Retrospective Cohort Study of Young Women Spontaneously Choosing to Be Vaccinated against HPV: Outcomes from Their First Cervical Cancer Screening Test.
Annarosa Del Mistro, Jessica Battagello, Luca Weis, Vittoria Bressan, Vittorio Selle, Helena Frayle

Viruses· March 2021

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Leptomeningeal Carcinomatosis of a Poorly Differentiated Cervical Carcinoma Caused by Human Papillomavirus Type 18.
Pierpaolo Zorzato, Mattia Zambon, Silvia Gori, Helena Frayle, Maria Teresa Gervasi

Viruses· February 2021

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Combined use of cytology, p16 immunostaining and genotyping for triage of women positive for high-risk human papillomavirus at primary screening.
Jack Cuzick, Rachael Adcock, Francesca Carozzi, Anna Gillio-Tos, Laura De Marco, Helena Frayle

Int J Cancer· October 2020

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Age-independent increasing prevalence of Human Papillomavirus-driven oropharyngeal carcinomas in North-East Italy.
Annarosa Del Mistro, Helena Frayle, Anna Menegaldo, Niccolò Favaretto, Silvia Gori

Sci Rep· June 2020

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HPV testing for cervical cancer screening: technical improvement of laboratory logistics and good clinical performance of the cobas 6800 in comparison to the 4800 system.
Helena Frayle, Silvia Gori, Martina Rizzi, Bianca Nives Graziani, Elisa Vian

BMC Womens Health· March 2019

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Human papilloma virus genotyping for the cross-sectional and longitudinal probability of developing cervical intraepithelial neoplasia grade 2 or more.
Annarosa Del Mistro, Rachael Adcock, Francesca Carozzi, Anna Gillio-Tos, Laura De Marco, Helena Frayle

Int J Cancer· July 2018

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Methylation analysis and HPV genotyping of self-collected cervical samples from women not responding to screening invitation and review of the literature.
Annarosa Del Mistro, Helena Frayle, Martina Rizzi, Gianpiero Fantin, Antonio Ferro

PLoS One· August 2017

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Determinants of Viral Oncogene E6-E7 mRNA Overexpression in a Population-Based Large Sample of Women Infected by High-Risk Human Papillomavirus Types.
Paolo Giorgi Rossi, Simonetta Bisanzi, Elena Allia, Alessandra Mongia, Francesca Carozzi, Helena Frayle

J Clin Microbiol· April 2017

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Efficacy of self-sampling in promoting participation to cervical cancer screening also in subsequent round.
Annarosa Del Mistro, Helena Frayle, Antonio Ferro, Gianpiero Fantin, Emma Altobelli

Prev Med Rep· March 2017

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HPV testing for primary cervical screening: Laboratory issues and evolving requirements for robust quality assurance.
Francesca Maria Carozzi, Annarosa Del Mistro, Kate Cuschieri, Helena Frayle, Cristina Sani

J Clin Virol· March 2016

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Cervical cancer screening by high risk HPV testing in routine practice: results at one year recall of high risk HPV-positive and cytology-negative women.
Annarosa Del Mistro, Helena Frayle, Antonio Ferro, Susanna Callegaro, Annamaria Del Sole

J Med Screen· March 2014

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[Molecular diagnosis of retinoblastoma: molecular epidemiology and genetic counseling].
Javier Alonso, Itziar Palacios, Angelo Gámez, Isabel Camino, Helena Frayle

Med Clin (Barc)· March 2006

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Identification of 26 new constitutional RB1 gene mutations in Spanish, Colombian, and Cuban retinoblastoma patients.
Javier Alonso, Helena Frayle, Ibis Menéndez, Andrés López, Purificación García-Miguel

Hum Mutat· January 2005

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Two independent RB1-inactivating mutations in peripheral blood DNA of a hereditary retinoblastoma patient.
Javier Alonso, Ibis Menéndez, Andrés López, Helena Frayle, Nora Ruisánchez

Genes Chromosomes Cancer· July 2004

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