Publications by authors named "Helena Viola"

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Novel Peptide Therapeutics Targeting the L-Type Calcium Channel Prevent Hypertrophic Cardiomyopathy by Decreasing Mitochondrial Energetics.
Teagan S Er, Daniel Reinke, Alice J Francis, Tanya M Solomon, Helena M Viola

JACC Basic Transl Sci· October 2025

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Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease.
Vanessa S Fear, Catherine A Forbes, Nicole C Shaw, Kathryn O Farley, Jessica L Mantegna, Helena Viola

Stem Cell Res Ther· December 2023

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Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy.
Henrietta Cserne Szappanos, Helena M Viola, Danica W Ito, Seakcheng Lim, Melissa Mangala

Sci Rep· July 2023

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A maladaptive feedback mechanism between the extracellular matrix and cytoskeleton contributes to hypertrophic cardiomyopathy pathophysiology.
Helena M Viola, Caitlyn Richworth, Tanya Solomon, Ian L Chin, Henrietta Cserne Szappanos

Commun Biol· January 2023

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A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance.
Giulia Rossetti, Judith A Ermer, Maike Stentenbach, Stefan J Siira, Tara R Richman, Helena M Viola

Sci Adv· September 2021

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Fidelity and coordination of mitochondrial protein synthesis in health and disease.
Danielle L Rudler, Laetitia A Hughes, Helena M Viola, Livia C Hool, Oliver Rackham

J Physiol· July 2021

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Preventative therapeutic approaches for hypertrophic cardiomyopathy.
Tanya Solomon, Aleksandra Filipovska, Livia Hool, Helena Viola

J Physiol· July 2021

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Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan.
Tara R Richman, Judith A Ermer, Stefan J Siira, Irina Kuznetsova, Christopher A Brosnan, Helena M Viola

Aging Cell· July 2021

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Lack of Strategic Funding and Long-Term Job Security Threaten to Have Profound Effects on Cardiovascular Researcher Retention in Australia.
Rachel E Climie, Jason H Y Wu, Anna C Calkin, Niamh Chapman, Sally C Inglis, Helena M Viola

Heart Lung Circ· November 2020

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A dendronized polymer variant that facilitates safe delivery of a calcium channel antagonist to the heart.
Helena M Viola, Ashay A Shah, Jessica A Kretzmann, Cameron W Evans, Marck Norret

Nanomedicine· October 2020

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Characterization and validation of a preventative therapy for hypertrophic cardiomyopathy in a murine model of the disease.
Helena M Viola, Ashay A Shah, Victoria P A Johnstone, Henrietta Cserne Szappanos, Mark P Hodson

Proc Natl Acad Sci U S A· September 2020

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Fidelity of translation initiation is required for coordinated respiratory complex assembly.
Danielle L Rudler, Laetitia A Hughes, Kara L Perks, Tara R Richman, Irina Kuznetsova, Helena M Viola

Sci Adv· December 2019

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TGF-β-induced fibrotic stress increases G-quadruplex formation in human fibroblasts.
Priyanka Toshniwal, Michelle Nguyen, Aurore Guédin, Helena Viola, Diwei Ho

FEBS Lett· November 2019

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Impaired calcium handling and mitochondrial metabolic dysfunction as early markers of hypertrophic cardiomyopathy.
Helena M Viola, Livia C Hool

Arch Biochem Biophys· April 2019

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Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions.
Montse Olivé, Martin Engvall, Gianina Ravenscroft, Macarena Cabrera-Serrano, Hong Jiao, Helena M Viola

Nat Commun· March 2019

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Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z.
Stefan J Siira, Giulia Rossetti, Tara R Richman, Kara Perks, Judith A Ermer, Helena M Viola

EMBO Rep· October 2018

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A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery.
Katrin Hoffmann, Nadia Milech, Suzy M Juraja, Paula T Cunningham, Shane R Stone, Helena M Viola

Sci Rep· August 2018

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A Morpholino Oligomer Therapy Regime That Restores Mitochondrial Function and Prevents Cardiomyopathy.
Helena M Viola, Victoria P A Johnstone, Abbie M Adams, Susan Fletcher, Livia C Hool

JACC Basic Transl Sci· June 2018

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PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly.
Kara L Perks, Giulia Rossetti, Irina Kuznetsova, Laetitia A Hughes, Judith A Ermer, Helena M Viola

Cell Rep· April 2018

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Real-Time Bioimpedance Sensing of Antifibrotic Drug Action in Primary Human Cells.
Maryam Parviz, Priyanka Toshniwal, Helena M Viola, Livia C Hool, P Mark W Fear

ACS Sens· October 2017

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Adult-onset obesity is triggered by impaired mitochondrial gene expression.
Kara L Perks, Nicola Ferreira, Tara R Richman, Judith A Ermer, Irina Kuznetsova, Helena M Viola

Sci Adv· August 2017

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Auto-regulation in the powerhouse.
Helena M Viola, Livia C Hool

Elife· July 2017

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L-type calcium channel: Clarifying the "oxygen sensing hypothesis".
Henrietta Cserne Szappanos, Helena Viola, Livia C Hool

Int J Biochem Cell Biol· May 2017

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Dystrophic Cardiomyopathy-Potential Role of Calcium in Pathogenesis, Treatment and Novel Therapies.
Victoria P A Johnstone, Helena M Viola, Livia C Hool

Genes (Basel)· March 2017

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The impact of non-severe burn injury on cardiac function and long-term cardiovascular pathology.
Emily O'Halloran, Amit Shah, Lawrence Dembo, Livia Hool, Helena Viola

Sci Rep· October 2016

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