Publications by authors named "Helene Chaignot"

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The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain.
Gerard M P Giblin, Rino A Bit, Susan H Brown, Hélène M Chaignot, Anita Chowdhury

Bioorg Med Chem Lett· January 2007

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Discovery of novel biaryl heterocyclic EP1 receptor antagonists.
Adrian Hall, Rino A Bit, Susan H Brown, Helene M Chaignot, Iain P Chessell

Bioorg Med Chem Lett· May 2006

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The design of potent, non-peptidic inhibitors of hepatitis C protease.
David M Andrews, Helene M Chaignot, Barry A Coomber, Mike D Dowle, S Lucy Hind

Eur J Med Chem· April 2003

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Design and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease.
Martin J Slater, David M Andrews, Graham Baker, Susanne S Bethell, Seb Carey, Helene Chaignot

Bioorg Med Chem Lett· December 2002

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Pyrrolidine-5,5-trans-lactams. 1. Synthesis and incorporation into inhibitors of hepatitis C virus NS3/4A protease.
David M Andrews, Seb J Carey, Helene Chaignot, Barry A Coomber, Norman M Gray

Org Lett· December 2002

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Pyrrolidine-5,5-trans-lactams. 2. The use of X-ray crystal structure data in the optimization of P3 and P4 substituents.
David M Andrews, Helene Chaignot, Barry A Coomber, Andrew C Good, S Lucy Hind

Org Lett· December 2002

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