Publications by authors named "Helmut Holtmann"

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Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.
Katharina Essig, Nina Kronbeck, Joao C Guimaraes, Claudia Lohs, Andreas Schlundt, Helmut Holtmann

Nat Commun· September 2018

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A translational silencing function of MCPIP1/Regnase-1 specified by the target site context.
Gesine Behrens, Reinhard Winzen, Nina Rehage, Anneke Dörrie, Monika Barsch, Helmut Holtmann

Nucleic Acids Res· May 2018

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IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IκBζ mRNA.
Sonam Dhamija, Anneke Doerrie, Reinhard Winzen, Oliver Dittrich-Breiholz, Azadeh Taghipour, Helmut Holtmann

J Biol Chem· November 2016

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Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.
Katharina M Jeltsch, Desheng Hu, Sven Brenner, Jessica Zöller, Gitta A Heinz, Helmut Holtmann

Nat Immunol· November 2014

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The role of mammalian MAPK signaling in regulation of cytokine mRNA stability and translation.
Christopher Tiedje, Helmut Holtmann, Matthias Gaestel

J Interferon Cytokine Res· April 2014

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Interleukin-17 (IL-17) and IL-1 activate translation of overlapping sets of mRNAs, including that of the negative regulator of inflammation, MCPIP1.
Sonam Dhamija, Reinhard Winzen, Anneke Doerrie, Gesine Behrens, Nancy Kuehne, Helmut Holtmann

J Biol Chem· June 2013

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The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.
Christopher Tiedje, Natalia Ronkina, Mohammad Tehrani, Sonam Dhamija, Kathrin Laass, Helmut Holtmann

PLoS Genet· September 2012

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Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism.
Sonam Dhamija, Nancy Kuehne, Reinhard Winzen, Anneke Doerrie, Oliver Dittrich-Breiholz, Helmut Holtmann

J Biol Chem· September 2011

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c-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies.
Katharina Rzeczkowski, Knut Beuerlein, Helmut Müller, Oliver Dittrich-Breiholz, Heike Schneider, Helmut Holtmann

J Cell Biol· August 2011

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IL-1-induced post-transcriptional mechanisms target overlapping translational silencing and destabilizing elements in IκBζ mRNA.
Sonam Dhamija, Anneke Doerrie, Reinhard Winzen, Oliver Dittrich-Breiholz, Azadeh Taghipour, Helmut Holtmann

J Biol Chem· September 2010

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Reduced transcript stabilization restricts TNF-alpha expression in RAW264.7 macrophages infected with pathogenic mycobacteria: evidence for an involvement of lipomannan.
Tina Basler, Helmut Holtmann, Jens Abel, Torsten Eckstein, Wolfgang Baumer

J Leukoc Biol· January 2010

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The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.
Kristian Otkjaer, Helmut Holtmann, Tue Wenzel Kragstrup, Søren Riis Paludan, Claus Johansen

PLoS One· January 2010

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Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets.
Reinhard Winzen, Basant Kumar Thakur, Oliver Dittrich-Breiholz, Meera Shah, Natalie Redich, Helmut Holtmann

Mol Cell Biol· December 2007

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Inhibition of mRNA deadenylation and degradation by different types of cell stress.
Gayatri Gowrishankar, Reinhard Winzen, Oliver Dittrich-Breiholz, Natalie Redich, Michael Kracht, Helmut Holtmann

Biol Chem· March 2006

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Inhibition of mRNA deadenylation and degradation by ultraviolet light.
Gayatri Gowrishankar, Reinhard Winzen, Frank Bollig, Beniam Ghebremedhin, Natalie Redich, Helmut Holtmann

Biol Chem· December 2005

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Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR.
Reinhard Winzen, Gayatri Gowrishankar, Frank Bollig, Natalie Redich, Klaus Resch, Helmut Holtmann

Mol Cell Biol· June 2004

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Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization.
Frank Bollig, Reinhard Winzen, Matthias Gaestel, Susanne Kostka, Klaus Resch, Helmut Holtmann

Biochem Biophys Res Commun· February 2003

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Evidence for general stabilization of mRNAs in response to UV light.
Frank Bollig, Reinhard Winzen, Michael Kracht, Beniam Ghebremedhin, Birgit Ritter, Helmut Holtmann

Eur J Biochem· December 2002

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Multiple control of interleukin-8 gene expression.
Elke Hoffmann, Oliver Dittrich-Breiholz, Helmut Holtmann, Michael Kracht

J Leukoc Biol· November 2002

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MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels.
Armin Neininger, Dimitris Kontoyiannis, Alexey Kotlyarov, Reinhard Winzen, Rolf Eckert, Helmut Holtmann

J Biol Chem· February 2002

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