Publications by authors named "Helmut Laumen"

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Hereditary chronic pancreatitis induced plasticity cooperates with mutant Kras in early pancreatic carcinogenesis.
Tanvi Vikrant Inamdar, Ferdinand Krannich, Nico Hesselbarth, Atul Verma, Teresa Vauti, Helmut Laumen

Gut· December 2025

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Genome-wide discovery of enhancer - promoter interactions in the human pancreas using an improved Activity-By-Contact-based model.
Andreas W Schmidt, German Demidov, Ferdinand Krannich, Matthias Heinig, Stephan Ossowski, Helmut Laumen

Pancreatology· August 2025

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From Genes to Environment: Elucidating Pancreatic Carcinogenesis Through Genetically Engineered and Risk Factor-Integrated Mouse Models.
Bin Yan, Anne-Kristin Fritsche, Erik Haußner, Tanvi Vikrant Inamdar, Helmut Laumen

Cancers (Basel)· May 2025

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Induction of oxidative- and endoplasmic-reticulum-stress dependent apoptosis in pancreatic cancer cell lines by DDOST knockdown.
Richard Böhme, Andreas W Schmidt, Nico Hesselbarth, Guido Posern, Andrea Sinz, Helmut Laumen

Sci Rep· September 2024

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Genetic and functional analysis of chymotrypsin-like protease (CTRL) in chronic pancreatitis.
Katharina Eiseler, Lea Neppl, Andreas W Schmidt, Beate Rauscher, Maren Ewers, Helmut Laumen

Pancreatology· December 2023

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Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer.
Tom Kaune, Heidi Griesmann, Katharina Theuerkorn, Monika Hämmerle, Helmut Laumen

iScience· June 2023

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Loss-of-function variant in chymotrypsin like elastase 3B (CELA3B) is associated with non-alcoholic chronic pancreatitis.
Andrea Tóth, Alexandra Demcsák, Florence Zankl, Grzegorz Oracz, Lara Sophie Unger, Helmut Laumen

Pancreatology· September 2022

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Variants in the pancreatic CUB and zona pellucida-like domains 1 (CUZD1) gene in early-onset chronic pancreatitis - A possible new susceptibility gene.
Agnieszka Magdalena Rygiel, Lara Sophie Unger, Franziska Lena Sörgel, Emmanuelle Masson, Ryotaro Matsumoto, Helmut Laumen

Pancreatology· June 2022

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Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms.
Andreas W Schmidt, Andreas Kühnapfel, Holger Kirsten, Harald Grallert, Claus Hellerbrand, Helmut Laumen

Pancreatology· May 2022

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Loss of function TRPV6 variants are associated with chronic pancreatitis in nonalcoholic early-onset Polish and German patients.
Grzegorz Oracz, Michał Zaród, Maren Ewers, Helmut Laumen, Tomasz Gambin

Pancreatology· December 2021

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Targeting HDACs in Pancreatic Neuroendocrine Tumor Models.
Rosa Lynn Schmitz, Julia Weissbach, Jan Kleilein, Jessica Bell, Stefan Hüttelmaier, Helmut Laumen

Cells· June 2021

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Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.
Katharina Seltsam, Carola Pentner, Franziska Weigl, Stella Sutedjo, Constantin Zimmer, Helmut Laumen

Pancreatology· December 2020

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Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis.
Atsushi Masamune, Hiroshi Kotani, Franziska Lena Sörgel, Jian-Min Chen, Shin Hamada, Helmut Laumen

Gastroenterology· May 2020

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Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants.
Kerstin Matejka, Ferdinand Stückler, Michael Salomon, Regina Ensenauer, Eva Reischl, Helmut Laumen

PLoS One· January 2020

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Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
Denise Lasher, András Szabó, Atsushi Masamune, Jian-Min Chen, Xunjun Xiao, Helmut Laumen

Am J Gastroenterol· June 2019

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Genome-wide association study identifies inversion in the locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.
Jonas Rosendahl, Holger Kirsten, Eszter Hegyi, Peter Kovacs, Frank Ulrich Weiss, Helmut Laumen

Gut· October 2018

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Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.
Heekyoung Lee, Kun Qian, Christine von Toerne, Lena Hoerburger, Melina Claussnitzer, Helmut Laumen

Nucleic Acids Res· April 2017

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Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis.
Rona J Strawbridge, Helmut Laumen, Anders Hamsten, Michaela Breier, Harald Grallert

PLoS One· March 2017

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5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4(+) T Cells.
Colm E Nestor, Antonio Lentini, Cathrine Hägg Nilsson, Danuta R Gawel, Mika Gustafsson, Helmut Laumen

Cell Rep· July 2016

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Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.
Anna Halama, Marion Horsch, Gabriele Kastenmüller, Gabriele Möller, Pankaj Kumar, Helmut Laumen

Arch Biochem Biophys· January 2016

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Medium-chain dicarboxylic acylcarnitines as markers of n-3 PUFA-induced peroxisomal oxidation of fatty acids.
Jarlei Fiamoncini, Thais M Lima, Sandro M Hirabara, Josef Ecker, Renata Gorjão, Helmut Laumen

Mol Nutr Food Res· August 2015

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Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146.
Cornelia Then, Simone Wahl, Anna Kirchhofer, Harald Grallert, Susanne Krug, Helmut Laumen

PLoS One· February 2015

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Postprandial activation of metabolic and inflammatory signalling pathways in human peripheral mononuclear cells.
Kerstin Ehlers, Tina Brand, Adina Bangert, Hans Hauner, Helmut Laumen

Br J Nutr· June 2014

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Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon.
Derek Spieler, Maria Kaffe, Franziska Knauf, José Bessa, Juan J Tena, Helmut Laumen

Genome Res· April 2014

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Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.
Melina Claussnitzer, Simon N Dankel, Bernward Klocke, Harald Grallert, Viktoria Glunk, Helmut Laumen

Cell· January 2014

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