Publications by authors named "Helmut Spreitzer"

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Synthesis, Biological Evaluation, and Docking Studies of Antagonistic Hydroxylated Arecaidine Esters Targeting mAChRs.
Jonas Kilian, Marlon Millard, Marius Ozenil, Dominik Krause, Khadija Ghaderi, Helmut Spreitzer

Molecules· May 2022

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Unexpected scaffold rearrangement product of pirenzepine found in commercial samples.
Marius Ozenil, Lukas Skos, Alexander Roller, Natalie Gajic, Wolfgang Holzer, Helmut Spreitzer

Sci Rep· December 2021

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Discovery of melanin-concentrating hormone receptor 1 in brown adipose tissue.
Cécile Philippe, Eva-Maria Klebermass, Theresa Balber, Oana C Kulterer, Markus Zeilinger, Helmut Spreitzer

Ann N Y Acad Sci· June 2021

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Synthesis, Biological, and Computational Evaluation of Antagonistic, Chiral Hydrobenzoin Esters of Arecaidine Targeting mAChR M1.
Marius Ozenil, Jonas Aronow, Daniela Piljak, Chrysoula Vraka, Wolfgang Holzer, Helmut Spreitzer

Pharmaceuticals (Basel)· November 2020

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Enhanced arecoline derivatives as muscarinic acetylcholine receptor M1 ligands for potential application as PET radiotracers.
Marius Ozenil, Katharina Pacher, Theresa Balber, Chrysoula Vraka, Alexander Roller, Helmut Spreitzer

Eur J Med Chem· October 2020

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Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes.
Theresa Balber, Katarína Benčurová, Florian Wolfgang Kiefer, Oana Cristina Kulterer, Eva-Maria Klebermass, Helmut Spreitzer

Front Endocrinol (Lausanne)· June 2019

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SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [F]FE@SNAP and [C]SNAP-7941.
Cécile Philippe, Markus Zeilinger, Monika Dumanic, Florian Pichler, Lukas Fetty, Helmut Spreitzer

Mol Imaging Biol· April 2019

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Pharmacy Practice and Education in Austria.
Thierry Langer, Helmut Spreitzer, Teresa Ditfurth, Gunar Stemer, Jeffrey Atkinson

Pharmacy (Basel)· June 2018

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New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics.
Markus Zeilinger, Florian Pichler, Lukas Nics, Wolfgang Wadsak, Helmut Spreitzer

EJNMMI Res· December 2017

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In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [C]SNAP-7941 and [F]FE@SNAP reveal specific uptake in the ventricular system.
Markus Zeilinger, Monika Dumanic, Florian Pichler, Lubos Budinsky, Wolfgang Wadsak, Helmut Spreitzer

Sci Rep· August 2017

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[(18)F]FE@SNAP-a specific PET tracer for melanin-concentrating hormone receptor 1 imaging?
Cécile Philippe, Daniela Haeusler, Thomas Scherer, Clemens Fürnsinn, Markus Zeilinger, Helmut Spreitzer

EJNMMI Res· December 2016

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[18F]FE@SUPPY: a suitable PET tracer for the adenosine A3 receptor? An in vivo study in rodents.
Daniela Haeusler, Claudia Kuntner, Lukas Nics, Markus Savli, Markus Zeilinger, Helmut Spreitzer

Eur J Nucl Med Mol Imaging· April 2015

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Synthesis and in silico evaluation of novel compounds for PET-based investigations of the norepinephrine transporter.
Catharina Neudorfer, Amir Seddik, Karem Shanab, Andreas Jurik, Christina Rami-Mark, Helmut Spreitzer

Molecules· January 2015

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Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer's disease.
Catharina Neudorfer, Karem Shanab, Andreas Jurik, Veronika Schreiber, Carolina Neudorfer, Helmut Spreitzer

Bioorg Med Chem Lett· September 2014

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Comparative autoradiographic in vitro investigation of melanin concentrating hormone receptor 1 ligands in the central nervous system.
Cécile Philippe, Daniela Haeusler, Florian Fuchshuber, Helmut Spreitzer, Helmut Viernstein

Eur J Pharmacol· July 2014

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A one-step microwave-assisted synthetic method for an O/S-chemoselective route to derivatives of the first adenosine A3 PET radiotracer.
Karem Shanab, Catharina Neudorfer, Wolfgang Holzer, Markus Mitterhauser, Wolfgang Wadsak, Helmut Spreitzer

Molecules· April 2014

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Synthesis, radiosynthesis and first in vitro evaluation of novel PET-tracers for the dopamine transporter: [(11)C]IPCIT and [(18)F]FE@IPCIT.
Christina Rami-Mark, Birgit Bornatowicz, Cornel Fink, Paul Otter, Johanna Ungersboeck, Helmut Spreitzer

Bioorg Med Chem· December 2013

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Preclinical in vitro &in vivo evaluation of [(11)C]SNAP-7941 - the first PET tracer for the melanin concentrating hormone receptor 1.
Cécile Philippe, Lukas Nics, Markus Zeilinger, Claudia Kuntner, Thomas Wanek, Helmut Spreitzer

Nucl Med Biol· October 2013

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Synthesis and antiproliferative activity of new cytotoxic tri- and tetraazabenzo[3,2-a]fluorene-5,6-dione derivatives.
Theerachart Leepasert, Manochehr Shahabi, Karem Shanab, Eva Schirmer, Wolfgang Holzer, Helmut Spreitzer

Bioorg Med Chem Lett· October 2013

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Preparation and First Preclinical Evaluation of [(18)F]FE@SNAP: A Potential PET Tracer for the Melanin-Concentrating Hormone Receptor-1 (MCHR1).
Cécile Philippe, Lukas Nics, Markus Zeilinger, Eva Schirmer, Helmut Spreitzer

Sci Pharm· October 2013

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Syntheses of precursors and reference compounds of the melanin-concentrating hormone receptor 1 (MCHR1) tracers [¹¹C]SNAP-7941 and [¹⁸F]FE@SNAP for positron emission tomography.
Eva Schirmer, Karem Shanab, Barbara Datterl, Catharina Neudorfer, Markus Mitterhauser, Helmut Spreitzer

Molecules· September 2013

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Synthesis and biological evaluation of new cytotoxic indazolo[4,3-gh]isoquinolinone derivatives.
Manochehr Shahabi, Eva Schirmer, Karem Shanab, Theerachart Leepasert, Jana Ruzicka, Helmut Spreitzer

Bioorg Med Chem Lett· March 2013

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Development and automation of a novel NET-PET tracer: [11C]Me@APPI.
Christina Mark, Birgit Bornatowicz, Markus Mitterhauser, Matthias Hendl, Lukas Nics, Helmut Spreitzer

Nucl Med Biol· February 2013

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[¹⁸F]FE@SNAP-A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): microfluidic and vessel-based approaches.
Cécile Philippe, Johanna Ungersboeck, Eva Schirmer, Milica Zdravkovic, Lukas Nics, Helmut Spreitzer

Bioorg Med Chem· October 2012

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Microfluidic preparation of [18F]FE@SUPPY and [18F]FE@SUPPY:2--comparison with conventional radiosyntheses.
Johanna Ungersboeck, Cécile Philippe, Leonhard-Key Mien, Daniela Haeusler, Karem Shanab, Helmut Spreitzer

Nucl Med Biol· April 2011

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