Publications by authors named "Hemantkumar Chavan"

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Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice.
Xuan Qin, John M Hakenjos, Kevin R MacKenzie, Mercedes Barzi, Hemantkumar Chavan

Drug Metab Dispos· February 2022

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Lack of Toxicity in Nonhuman Primates Receiving Clinically Relevant Doses of an AAV9.U7snRNA Vector Designed to Induce Exon 2 Skipping.
Liubov V Gushchina, Emma C Frair, Natalie Rohan, Adrienne J Bradley, Tabatha R Simmons, Hemantkumar D Chavan

Hum Gene Ther· September 2021

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Alternol eliminates excessive ATP production by disturbing Krebs cycle in prostate cancer.
Changlin Li, Chenchen He, Ying Xu, Haixia Xu, Yuzhe Tang, Hemantkumar Chavan

Prostate· May 2019

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Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice.
Hua Wang, Hong-Min Ni, Xiaojuan Chao, Xiaowen Ma, Yssa Ann Rodriguez, Hemantkumar Chavan

Redox Biol· April 2019

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Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription.
Ram P Kumar, Soma Ray, Pratik Home, Biswarup Saha, Bhaswati Bhattacharya, Hemantkumar Chavan

Development· October 2018

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Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice.
Xiaojuan Chao, Shaogui Wang, Katrina Zhao, Yuan Li, Jessica A Williams, Hemantkumar Chavan

Gastroenterology· September 2018

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Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression.
Dhruv Kumar, Jacob New, Vikalp Vishwakarma, Radhika Joshi, Jonathan Enders, Hemantkumar Chavan

Cancer Res· July 2018

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Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response.
Hemantkumar Chavan, Pamela Christudoss, Kristen Mickey, Robert Tessman, Hong-Min Ni

Oxid Med Cell Longev· March 2017

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Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1-AKT-mTOR Axis in Mice.
Yifeng Wang, Yifeng Ding, Jibiao Li, Hemantkumar Chavan, David Matye

Cell Mol Gastroenterol Hepatol· March 2017

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Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice.
Bharat Bhushan, Hemantkumar Chavan, Prachi Borude, Yuchao Xie, Kuo Du

Toxicol Sci· February 2017

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Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1.
Jibiao Li, Yifeng Wang, David J Matye, Hemantkumar Chavan, Partha Krishnamurthy

J Biol Chem· January 2017

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Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction.
Kuo Du, Anup Ramachandran, James L Weemhoff, Hemantkumar Chavan, Yuchao Xie

Toxicol Sci· December 2016

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Metabolomics reveals the formation of aldehydes and iminium in gefitinib metabolism.
Xing Liu, Yuanfu Lu, Xinfu Guan, Bingning Dong, Hemantkumar Chavan

Biochem Pharmacol· September 2015

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Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver.
Hemantkumar Chavan, Feng Li, Robert Tessman, Kristen Mickey, Kenneth Dorko

J Biol Chem· March 2015

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Efficient purification and reconstitution of ATP binding cassette transporter B6 (ABCB6) for functional and structural studies.
Hemantkumar Chavan, Mohiuddin Md Taimur Khan, George Tegos, Partha Krishnamurthy

J Biol Chem· August 2013

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A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.
Kishore Polireddy, Mohiuddin Md Taimur Khan, Hemantkumar Chavan, Susan Young, Xiaochao Ma

PLoS One· March 2013

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Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR).
Hemantkumar Chavan, Partha Krishnamurthy

J Biol Chem· September 2012

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Functional significance of the ATP-binding cassette transporter B6 in hepatocellular carcinoma.
Kishore Polireddy, Hemantkumar Chavan, Bashar A Abdulkarim, Partha Krishnamurthy

Mol Oncol· October 2011

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The ATP-binding cassette transporter ABCB6 is induced by arsenic and protects against arsenic cytotoxicity.
Hemantkumar Chavan, Mahitha Oruganti, Partha Krishnamurthy

Toxicol Sci· April 2011

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Proteomic analysis of wild type and arsenite-resistant Leishmania donovani.
Shruti Sharma, Gaganmeet Singh, Hemantkumar D Chavan, Chinmoy S Dey

Exp Parasitol· December 2009

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Proteomic analysis of miltefosine-resistant Leishmania reveals the possible involvement of eukaryotic initiation factor 4A (eIF4A).
Gaganmeet Singh, Hemantkumar D Chavan, Chinmoy S Dey

Int J Antimicrob Agents· June 2008

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Confocal microscopic investigation of tubulin distribution and effect of paclitaxel on posttranslationally modified tubulins in sodium arsenite resistant Leishmania donovani.
Hemantkumar D Chavan, Gaganmeet Singh, Chinmoy S Dey

Exp Parasitol· July 2007

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