Publications by authors named "Henry Guzik"

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Tetrahydroquinoline sulfonamides as gamma-secretase inhibitors.
Theodros Asberom, Thomas A Bara, John W Clader, William J Greenlee, Henry S Guzik

Bioorg Med Chem Lett· January 2007

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2,6-Disubstituted N-arylsulfonyl piperidines as gamma-secretase inhibitors.
Dmitri A Pissarnitski, Theodros Asberom, Thomas A Bara, Alex V Buevich, John W Clader, Henry S Guzik

Bioorg Med Chem Lett· January 2007

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Bicyclo[3.1.0]hexyl urea melanin concentrating hormone (MCH) receptor-1 antagonists: impacting hERG liability via aryl modifications.
Mark D McBriar, Henry Guzik, Sherry Shapiro, Ruo Xu, Jaroslava Paruchova

Bioorg Med Chem Lett· August 2006

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Bicyclic[4.1.0]heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists.
Ruo Xu, Shengjian Li, Jaroslava Paruchova, Mark D McBriar, Henry Guzik

Bioorg Med Chem· May 2006

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Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.
Mark D McBriar, Henry Guzik, Sherry Shapiro, Jaroslava Paruchova, Ruo Xu

J Med Chem· April 2006

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Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.
Timothy J Kowalski, Brian D Spar, Blair Weig, Constance Farley, John Cook, Henry Guzik

Eur J Pharmacol· March 2006

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Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male ED.
Craig D Boyle, Ruo Xu, Theodros Asberom, Samuel Chackalamannil, John W Clader, Henry Guzik

Bioorg Med Chem Lett· May 2005

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Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.
Mark D McBriar, Henry Guzik, Ruo Xu, Jaroslava Paruchova, Shengjian Li

J Med Chem· April 2005

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Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048.
Raymond G Lovey, Anil K Saksena, Viyyoor M Girijavallabhan, Paul Blundell, Henry Guzik

Bioorg Med Chem Lett· July 2002

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