Publications by authors named "Herbert Treutlein"

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Tropomyosin1 isoforms underlie epithelial to mesenchymal plasticity, metastatic dissemination, and resistance to chemotherapy in high-grade serous ovarian cancer.
Tong Xu, Mathijs P Verhagen, Miriam Teeuwssen, Wenjie Sun, Rosalie Joosten, Herbert R Treutlein

Cell Death Differ· March 2024

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A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.
Benny J Evison, James T Palmer, Gilles Lambert, Herbert Treutlein, Jun Zeng

Bioorg Med Chem· March 2020

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Computational Prediction of the Epitopes of HA1 Protein of Influenza Viruses to its Neutralizing Antibodies.
Xiaoyan Zeng, Fiona S Legge, Chao Huang, Xiao Zhang, Yongjun Jiao, Herbert R Treutlein

Antibodies (Basel)· December 2018

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On-target action of anti-tropomyosin drugs regulates glucose metabolism.
Anthony J Kee, Jayshan Chagan, Jeng Yie Chan, Nicole S Bryce, Christine A Lucas, Herbert Treutlein

Sci Rep· March 2018

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Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs.
Mark A Currier, Justine R Stehn, Ashleigh Swain, Duo Chen, Jeff Hook, Herbert Treutlein

Mol Cancer Ther· August 2017

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Computational Identification of Antibody Epitopes on the Dengue Virus NS1 Protein.
Martina L Jones, Fiona S Legge, Kebaneilwe Lebani, Stephen M Mahler, Paul R Young, Herbert R Treutlein

Molecules· April 2017

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Antibody recognition of Shiga toxins (Stxs): computational identification of the epitopes of Stx2 subunit A to the antibodies 11E10 and S2C4.
Yongjun Jiao, Fiona S Legge, Xiaoyan Zeng, Herbert R Treutlein, Jun Zeng

PLoS One· January 2015

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A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells.
Justine R Stehn, Nikolas K Haass, Teresa Bonello, Melissa Desouza, Gregg Kottyan, Herbert Treutlein

Cancer Res· August 2013

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Computational identification of epitopes in the glycoproteins of novel bunyavirus (SFTS virus) recognized by a human monoclonal antibody (MAb 4-5).
Wenshuai Zhang, Xiaoyan Zeng, Li Zhang, Haiyan Peng, Yongjun Jiao, Herbert R Treutlein

J Comput Aided Mol Des· June 2013

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Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs).
Christopher J Burns, David G Bourke, Laura Andrau, Xianyong Bu, Susan A Charman, Herbert Treutlein

Bioorg Med Chem Lett· October 2009

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Discovery of 2-(alpha-methylbenzylamino) pyrazines as potent Type II inhibitors of FMS.
Christopher J Burns, Michael F Harte, Xianyong Bu, Emmanuelle Fantino, Marilena Giarrusso, Herbert Treutlein

Bioorg Med Chem Lett· February 2009

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Systematic comparison of empirical forcefields for molecular dynamic simulation of insulin.
Nevena Todorova, F Sue Legge, Herbert Treutlein, Irene Yarovsky

J Phys Chem B· September 2008

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Comparative study of insulin chain-B in isolated and monomeric environments under external stress.
Akin Budi, F Sue Legge, Herbert Treutlein, Irene Yarovsky

J Phys Chem B· July 2008

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Molecular dynamics simulations of a fibrillogenic peptide derived from apolipoprotein C-II.
F Sue Legge, Herbert Treutlein, Geoffrey J Howlett, Irene Yarovsky

Biophys Chem· November 2007

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Effect of frequency on insulin response to electric field stress.
Akin Budi, F Sue Legge, Herbert Treutlein, Irene Yarovsky

J Phys Chem B· May 2007

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Designing amino acid residues with single-conformations.
Tran T Tran, Herbert Treutlein, Antony W Burgess

Protein Eng Des Sel· September 2006

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The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor.
Isabelle S Lucet, Emmanuelle Fantino, Michelle Styles, Rebecca Bamert, Onisha Patel, Herbert Treutlein

Blood· January 2006

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Electric field effects on insulin chain-B conformation.
Akin Budi, F Sue Legge, Herbert Treutlein, Irene Yarovsky

J Phys Chem B· December 2005

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Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen.
Fiona M Smith, Christopher Vearing, Martin Lackmann, Herbert Treutlein, Juha Himanen

J Biol Chem· March 2004

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Modeling the epidermal growth factor -- epidermal growth factor receptor l2 domain interaction: implications for the ligand binding process.
Robert N Jorissen, Herbert R Treutlein, V Chandana Epa, Antony W Burgess

J Biomol Struct Dyn· June 2002

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Effects of thioamide substitutions on the conformation and stability of alpha- and 3(10)-helices.
Tran Trung Tran, Jun Zeng, Herbert Treutlein, Antony W Burgess

J Am Chem Soc· May 2002

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