Publications by authors named "Hideaki Obata"

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Randomized active-controlled study of the effect of intraoperative nitrous oxide on postoperative pain and numbness after posterior lumbar interbody fusion surgery.
Tadanao Hiroki, Hideo Suzuki, Nao Fujita, Takashi Suto, Noboru Tsukamoto, Hideaki Obata

J Anesth· December 2025

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Neuropathic pain after peripheral nerve injury in rats: a model using sciatic nerve clamping.
Michio Kumagai, Shigekazu Sugino, Toru Murakami, Hideaki Obata, Masanori Yamauchi

J Anesth· October 2025

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Gabapentin fails to provide analgesia while duloxetine remains effective in an attention deficit hyperactivity disorder rat model with neuropathic pain.
Xin He, Ikuya Koibuchi, Yuki Arai, Takashi Suto, Tadanao Hiroki, Hideaki Obata

Brain Res· September 2025

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Duloxetine deteriorates prefrontal noradrenergic pain facilitation, but reduces locus coeruleus activity to restore endogenous analgesia in chronic neuropathic pain state.
Yuki Arai, Takashi Suto, He Xin, Yoshitaka Honda, Tadanao Hiroki, Hideaki Obata

Sci Rep· June 2025

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Innovative therapeutic strategies using ADHD medications tailored to the behavioral characteristics of patients with chronic pain.
Satoshi Kasahara, Miwako Takahashi, Takashi Suto, Taito Morita, Hideaki Obata

Front Pharmacol· February 2025

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Rat model of attention-deficit hyperactivity disorder exhibits delayed recovery from acute incisional pain due to impaired descending noradrenergic inhibition.
Takashi Suto, Daiki Kato, Ikuya Koibuchi, Yuki Arai, Jo Ohta, Hideaki Obata

Sci Rep· April 2023

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Randomized active-controlled study of a single preoperative administration of duloxetine to treat postoperative pain and numbness after posterior lumbar interbody fusion surgery.
Tadanao Hiroki, Nao Fujita, Takashi Suto, Hideo Suzuki, Noboru Tsukamoto, Hideaki Obata

Medicine (Baltimore)· December 2022

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Effectiveness of ultrasound-guided fascia hydrorelease on the coracohumeral ligament in patients with global limitation of the shoulder range of motion: a pilot study.
Hiroaki Kimura, Masei Suda, Tadashi Kobayashi, Shigeki Suzuki, Sho Fukui, Hideaki Obata

Sci Rep· November 2022

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The efficacy of duloxetine depends on spinal cholinergic plasticity in neuropathic pain model rats.
Daiki Kato, Takashi Suto, Hideaki Obata, Shigeru Saito

IBRO Neurosci Rep· June 2022

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Spinal γ-Aminobutyric Acid Interneuron Plasticity Is Involved in the Reduced Analgesic Effects of Morphine on Neuropathic Pain.
Tadanao Hiroki, Takashi Suto, Jo Ohta, Shigeru Saito, Hideaki Obata

J Pain· April 2022

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Loss of endogenous analgesia leads to delayed recovery from incisional pain in a rat model of chronic neuropathic pain.
Jo Ohta, Takashi Suto, Daiki Kato, Tadanao Hiroki, Hideaki Obata

Brain Res· January 2020

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Spinal Activation of Tropomyosin Receptor Kinase-B Recovers the Impaired Endogenous Analgesia in Neuropathic Pain Rats.
Daiki Kato, Takashi Suto, Hideaki Obata, Shigeru Saito

Anesth Analg· August 2019

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Tropomyosin Receptor Kinase B Receptor Activation in the Locus Coeruleus Restores Impairment of Endogenous Analgesia at a Late Stage Following Nerve Injury in Rats.
Takashi Suto, Daiki Kato, Hideaki Obata, Shigeru Saito

J Pain· May 2019

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Strategies to Treat Chronic Pain and Strengthen Impaired Descending Noradrenergic Inhibitory System.
Ken-Ichiro Hayashida, Hideaki Obata

Int J Mol Sci· February 2019

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Repeated Administration of Duloxetine Suppresses Neuropathic Pain by Accumulating Effects of Noradrenaline in the Spinal Cord.
Sachiko Ito, Takashi Suto, Shigeru Saito, Hideaki Obata

Anesth Analg· January 2018

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Analgesic Mechanisms of Antidepressants for Neuropathic Pain.
Hideaki Obata

Int J Mol Sci· November 2017

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Repeated Administration of Amitriptyline in Neuropathic Pain: Modulation of the Noradrenergic Descending Inhibitory System.
Tadanao Hiroki, Takashi Suto, Shigeru Saito, Hideaki Obata

Anesth Analg· October 2017

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Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain.
Mi Chen, Hajime Hoshino, Shigeru Saito, Yang Yang, Hideaki Obata

Neurosci Lett· May 2017

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Brain morphological alternation in chronic pain patients with neuropathic characteristics.
Satomi Sugimine, Yuichi Ogino, Hiroaki Kawamichi, Hideaki Obata, Shigeru Saito

Mol Pain· December 2016

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Amitriptyline, but Not Pregabalin, Reverses the Attenuation of Noxious Stimulus-Induced Analgesia After Nerve Injury in Rats.
Hiroaki Matsuoka, Takashi Suto, Shigeru Saito, Hideaki Obata

Anesth Analg· August 2016

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A randomized placebo-controlled study of preoperative pregabalin for postoperative analgesia in patients with spinal surgery.
Nao Fujita, Masaru Tobe, Noboru Tsukamoto, Shigeru Saito, Hideaki Obata

J Clin Anesth· June 2016

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Effect of the Pulsatile Extracorporeal Membrane Oxygenation on Hemodynamic Energy and Systemic Microcirculation in a Piglet Model of Acute Cardiac Failure.
Hideshi Itoh, Shingo Ichiba, Yoshihito Ujike, Takuma Douguchi, Hideaki Obata

Artif Organs· January 2016

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In vivo and in vitro evaluation of novel μ-opioid receptor agonist compounds.
Yoshiaki Nikaido, Aya Kurosawa, Hitomi Saikawa, Satoshi Kuroiwa, Chiharu Suzuki, Hideaki Obata

Eur J Pharmacol· November 2015

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Antihyperalgesic effect of duloxetine and amitriptyline in rats after peripheral nerve injury: Influence of descending noradrenergic plasticity.
Hajime Hoshino, Hideaki Obata, Shigeru Saito

Neurosci Lett· August 2015

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The antihyperalgesic effects of intrathecal bupropion, a dopamine and noradrenaline reuptake inhibitor, in a rat model of neuropathic pain.
Hajime Hoshino, Hideaki Obata, Kunie Nakajima, Rie Mieda, Shigeru Saito

Anesth Analg· February 2015

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