Publications by authors named "Hideki Ohnota"

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Mutated GM-CSF-based CAR-T cells targeting CD116/CD131 complexes exhibit enhanced anti-tumor effects against acute myeloid leukaemia.
Aiko Hasegawa, Shoji Saito, Shogo Narimatsu, Shigeru Nakano, Mika Nagai, Hideki Ohnota

Clin Transl Immunology· May 2021

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Skeletal muscle cells derived from mouse skin cultures.
Hideki Ohnota, Hiromi Nakazawa, Morimichi Hayashi, Yuji Okuhara, Takayuki Honda

Biochem Biophys Res Commun· July 2020

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Novel oestrogen receptor β-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice.
Daimei Sasayama, Nobuhiro Sugiyama, Shigeru Yonekubo, Akiko Pawlak, Hiroyasu Murasawa, Hideki Ohnota

Sci Rep· July 2017

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Design, synthesis, and structure-activity relationship (SAR) of N-[7-(4-hydroxyphenoxy)-6-methylindan-4-yl]malonamic acids as thyroid hormone receptor β (TRβ) selective agonists.
Hiroaki Shiohara, Tetsuya Nakamura, Norihiko Kikuchi, Tomonaga Ozawa, Akane Matsuzawa, Hideki Ohnota

Bioorg Med Chem· February 2013

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Discovery of novel indane derivatives as liver-selective thyroid hormone receptor β (TRβ) agonists for the treatment of dyslipidemia.
Hiroaki Shiohara, Tetsuya Nakamura, Norihiko Kikuchi, Tomonaga Ozawa, Ryuichi Nagano, Hideki Ohnota

Bioorg Med Chem· June 2012

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Structure-activity relationship studies of 5-benzylaminoimidazo[1,2-c]pyrimidine-8-carboxamide derivatives as potent, highly selective ZAP-70 kinase inhibitors.
Akihito Hirabayashi, Harunobu Mukaiyama, Hiroaki Kobayashi, Hiroaki Shiohara, Satoko Nakayama, Hideki Ohnota

Bioorg Med Chem· January 2009

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Structure-activity relationship studies of imidazo[1,2-c]pyrimidine derivatives as potent and orally effective Syk family kinases inhibitors.
Akihito Hirabayashi, Harunobu Mukaiyama, Hiroaki Kobayashi, Hiroaki Shiohara, Satoko Nakayama, Hideki Ohnota

Bioorg Med Chem· October 2008

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A novel Syk family kinase inhibitor: design, synthesis, and structure-activity relationship of 1,2,4-triazolo[4,3-c]pyrimidine and 1,2,4-triazolo[1,5-c]pyrimidine derivatives.
Akihito Hirabayashi, Harunobu Mukaiyama, Hiroaki Kobayashi, Hiroaki Shiohara, Satoko Nakayama, Hideki Ohnota

Bioorg Med Chem· August 2008

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Novel pyrazolo[1,5-a]pyrimidines as c-Src kinase inhibitors that reduce IKr channel blockade.
Harunobu Mukaiyama, Toshihiro Nishimura, Satoko Kobayashi, Yoshimitsu Komatsu, Shinji Kikuchi, Hideki Ohnota

Bioorg Med Chem· January 2008

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Discovery of novel 2-anilinopyrazolo[1,5-a]pyrimidine derivatives as c-Src kinase inhibitors for the treatment of acute ischemic stroke.
Harunobu Mukaiyama, Toshihiro Nishimura, Hiroaki Shiohara, Satoko Kobayashi, Yoshimitsu Komatsu, Hideki Ohnota

Chem Pharm Bull (Tokyo)· June 2007

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Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
Morimichi Hayashi, Toru Tamura, Junji Kuroda, Hideki Ohnota, Nobuo Shibata

Toxicol Sci· March 2005

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Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
Morimichi Hayashi, Hideki Ohnota, Toru Tamura, Junji Kuroda, Nobuo Shibata

Arch Toxicol· August 2004

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