Publications by authors named "Hilda Garay"

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Characterization by LC-MS/MS analysis of KLH vaccine conjugated with a tick antigen peptide.
Satomy Pousa, Pablo E Ramos-Bermúdez, Vladimir Besada, Ania Cabrales-Rico, Osmany Guirola Cruz, Hilda Elisa Garay

Analyst· March 2025

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Stability in human serum and plasma of the HIV peptide drug candidate CIGB-210 and improved variants.
Carlos A Duarte, Ania Cabrales, Reina Echevarría, Taimí Paneque, Anna C Ramírez, Hilda Garay

Biotechnol Appl Biochem· February 2025

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Structural Characterization of the Dimers and Selective Synthesis of the Cyclic Analogues of the Antimicrobial Peptide Cm-p5.
Fidel E Morales-Vicente, Luis A Espinosa, Erbio Díaz-Pico, Ernesto M Martell, Melaine Gonzalez, Hilda E Garay

Antibiotics (Basel)· February 2025

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A hydrolyzed N-propionylthiosuccinimide linker is cleaved by metastable fragmentation, increasing reliability of conjugation site identification in conjugate vaccines.
Pablo E Ramos-Bermúdez, Satomy Pousa, Paulo Carvalho, Rodrigo Soares Caldeira Brant, Michel Batista, Hilda E Garay

Rapid Commun Mass Spectrom· September 2024

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Monoclonal antibody generated against Nile tilapia () IgT heavy chain using a peptide-based strategy.
Janet Velázquez, Lynn Cruz, Maylin Pérez-Bernal, Onel Valdivia, Arlette Haidar, Hilda Elisa Garay

Fish Shellfish Immunol Rep· December 2023

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Synergic effect of anticancer peptide CIGB-552 and Cisplatin in lung cancer models.
Yolanda Gomez Rodriguez, Brizaida Oliva Arguelles, Mario Riera-Romo, Jorge Fernandez-De-Cossio, Hilda Elisa Garay

Mol Biol Rep· April 2022

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Preliminary safety assessment of CIGB-210, an investigational peptide for HIV infection.
Anna C Ramírez-Suárez, Taimi Paneque-Guerrero, Dionne Casillas-Casanova, Karelia Cosme, Dania Bacardí, Hilda Garay

Hum Exp Toxicol· March 2022

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Evaluation of Cell-Penetrating Peptides as Mucosal Immune Enhancers for Nasal Vaccination.
Yadira Lobaina, Dioslaida Urquiza, Hilda Garay, Yasser Perera, Ke Yang

Int J Pept Res Ther· October 2021

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A first-in-class, first-in-human, phase I trial of CIGB-552, a synthetic peptide targeting COMMD1 to inhibit the oncogenic activity of NF-κB in patients with advanced solid tumors.
Maribel G Vallespi, Braulio Mestre, Maria A Marrero, Rolando Uranga, Diana Rey, Hilda E Garay

Int J Cancer· September 2021

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Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K carrier protein from Neisseria meningitidis.
Luis Javier González, Pedro E Encinosa Guzmán, Wendy Machado, Satomy Pousa, Alejandro Leyva, Hilda Garay

Anal Bioanal Chem· September 2021

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Antimicrobial Activity of Cyclic-Monomeric and Dimeric Derivatives of the Snail-Derived Peptide Cm-p5 against Viral and Multidrug-Resistant Bacterial Strains.
Melaine González-García, Fidel Morales-Vicente, Erbio Díaz Pico, Hilda Garay, Daniel G Rivera

Biomolecules· May 2021

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Monoclonal antibody against Nile tilapia (Oreochromis niloticus) IgM heavy chain: A valuable tool for detection and quantification of IgM and IgM cells.
Janet Velázquez, Alianet Rodríguez, Hasel Aragón, Arlette Haidar, Marcos González, Hilda Elsa Garay

Fish Shellfish Immunol· March 2021

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Autoantibodies against a novel citrullinated fibrinogen peptide related to smoking status, disease activity and therapeutic response to methotrexate in cuban patients with early rheumatoid arthritis.
Goitybell Martínez, Eugen Feist, Maité Martiatu, Hilda Garay, Bárbara Torres

Rheumatol Int· November 2020

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Functional and Mass Spectrometric Evaluation of an Anti-Tick Antigen Based on the P0 Peptide Conjugated to Bm86 Protein.
Alina Rodríguez Mallón, Luis Javier González, Pedro Enrique Encinosa Guzmán, Gervasio Henrique Bechara, Gustavo Seron Sanches, Hilda Garay

Pathogens· June 2020

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Design of a Helical-Stabilized, Cyclic, and Nontoxic Analogue of the Peptide Cm-p5 with Improved Antifungal Activity.
Fidel E Morales Vicente, Melaine González-Garcia, Erbio Diaz Pico, Elena Moreno-Castillo, Hilda E Garay

ACS Omega· November 2019

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A competitive ELISA for the quantitative determination of the novel anti-HIV drug candidate CIGB-210 in biological fluids.
Carlos A Duarte, Sheila Chávez, Yordanka Masforrol, Samy Puertas, Taimí Paneque, Hilda Garay

J Immunoassay Immunochem· May 2019

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Safety and Therapeutic Profile of a GnRH-Based Vaccine Candidate Directed to Prostate Cancer. A 10-Year Follow-Up of Patients Vaccinated With Heberprovac.
Jesús A Junco, Ranfis Rodríguez, Franklin Fuentes, Idania Baladrón, Maria D Castro, A Hilda Garay

Front Oncol· February 2019

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Characterization of low-abundance species in the active pharmaceutical ingredient of CIGB-300: A clinical-grade anticancer synthetic peptide.
Hilda Garay, Luis Ariel Espinosa, Yasser Perera, Aniel Sánchez, David Diago

J Pept Sci· June 2018

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The first report of cases of pet dogs with naturally occurring cancer treated with the antitumor peptide CIGB-552.
Maribel G Vallespi, Juan C Rodriguez, Lilibet Calaña Seoane, Patricia Alvarez, Hector Santana, Hilda Garay

Res Vet Sci· October 2017

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Development and validation of a bioanalytical method based on LC-MS/MS analysis for the quantitation of CIGB-814 peptide in plasma from Rheumatoid Arthritis patients.
Ania Cabrales-Rico, Yassel Ramos, Vladimir Besada, María Del Carmen Domínguez, Noraylis Lorenzo, Hilda Garay

J Pharm Biomed Anal· September 2017

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The intrinsic antimicrobial activity of citric acid-coated manganese ferrite nanoparticles is enhanced after conjugation with the antifungal peptide Cm-p5.
Carlos Lopez-Abarrategui, Viviana Figueroa-Espi, Maria B Lugo-Alvarez, Caroline D Pereira, Hilda Garay

Int J Nanomedicine· February 2017

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Gradual reduction of testosterone using a gonadotropin-releasing hormone vaccination delays castration resistance in a prostate cancer model.
Jesús A Junco Barranco, Robert P Millar, Franklin Fuentes, Eddy Bover, Eulogio Pimentel, Hilda Garay

Oncol Lett· August 2016

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Identification of Vimentin as a Potential Therapeutic Target against HIV Infection.
Celia Fernández-Ortega, Anna Ramírez, Dionne Casillas, Taimi Paneque, Raimundo Ubieta, Hilda Garay

Viruses· June 2016

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Comparative proteomic analysis of growth hormone secretagogue A233 treatment of murine macrophage cells J774A.2 indicates it has a role in antiviral innate response.
Rebeca Martínez, Teresa Núñez de Villavicencio-Díaz, Aniel Sánchez, Yassel Ramos, Jesús Noda Ferro, Hilda Garay

Biochem Biophys Rep· March 2016

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Macrocyclization of Peptide Side Chains by the Ugi Reaction: Achieving Peptide Folding and Exocyclic N-Functionalization in One Shot.
Aldrin V Vasco, Carlos S Pérez, Fidel E Morales, Hilda E Garay, Dimitar Vasilev

J Org Chem· July 2015

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