Publications by authors named "Hiroyasu Aoki"

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A pan-immunotherapy signature to predict intratumoral CD8 T cell expansions.
Munetomo Takahashi, Mikiya Tsunoda, Hiroyasu Aoki, Masaki Kurosu, Haru Ogiwara

Nat Commun· October 2025

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T follicular helper 1 cells in blood potentially mirror salivary gland-infiltrating T cells in Sjögren's disease.
Saori Abe, Hiroto Tsuboi, Hiroyasu Aoki, Hirofumi Toko, Fumika Honda

Sci Rep· July 2025

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CD8 T cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance.
Hiroyasu Aoki, Masahiro Kitabatake, Haruka Abe, Peng Xu, Mikiya Tsunoda

Cell Rep· March 2024

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Clonal Spreading of Tumor-Infiltrating T Cells Underlies the Robust Antitumor Immune Responses.
Hiroyasu Aoki, Mikiya Tsunoda, Haru Ogiwara, Haruka Shimizu, Haruka Abe

Cancer Immunol Res· June 2023

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Commensal Bacteria and the Lung Environment Are Responsible for Th2-Mediated Memory Yielding Natural IgE in MyD88-Deficient Mice.
Shunsuke Amano, Kei Haniuda, Saori Fukao, Hiroyasu Aoki, Satoshi Ueha

J Immunol· April 2023

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Transition of Antibody Titers after SARS-CoV-2 mRNA Vaccination in Japanese Healthcare Workers.
Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Ryutaro Furukawa, Makiko Konda, Hiroyasu Aoki

Jpn J Infect Dis· January 2023

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TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.
Shigeyuki Shichino, Satoshi Ueha, Shinichi Hashimoto, Tatsuro Ogawa, Hiroyasu Aoki

Commun Biol· June 2022

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Revealing Clonal Responses of Tumor-Reactive T-Cells Through T Cell Receptor Repertoire Analysis.
Hiroyasu Aoki, Shigeyuki Shichino, Kouji Matsushima, Satoshi Ueha

Front Immunol· March 2022

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Proportional Tumor Infiltration of T Cells Circulation Duplicates the T Cell Receptor Repertoire in a Bilateral Tumor Mouse Model.
Mikiya Tsunoda, Hiroyasu Aoki, Haruka Shimizu, Shigeyuki Shichino, Kouji Matsushima

Front Immunol· December 2021

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Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8 T Cells.
Chang-Yu Chen, Satoshi Ueha, Yoshiro Ishiwata, Shigeyuki Shichino, Shoji Yokochi, Hiroyasu Aoki

Cancer Immunol Res· October 2021

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Greater extent of blood-tumor TCR repertoire overlap is associated with favorable clinical responses to PD-1 blockade.
Hiroyasu Aoki, Satoshi Ueha, Yoshiaki Nakamura, Shigeyuki Shichino, Hiromichi Nakajima

Cancer Sci· August 2021

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Transient Depletion of CD4 Cells Induces Remodeling of the TCR Repertoire in Gastrointestinal Cancer.
Hiroyasu Aoki, Satoshi Ueha, Shigeyuki Shichino, Haru Ogiwara, Kohei Shitara

Cancer Immunol Res· June 2021

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TCR Repertoire Analysis Reveals Mobilization of Novel CD8 T Cell Clones Into the Cancer-Immunity Cycle Following Anti-CD4 Antibody Administration.
Hiroyasu Aoki, Satoshi Ueha, Shigeyuki Shichino, Haru Ogiwara, Shin-Ichi Hashimoto

Front Immunol· October 2019

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First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors.
Kohei Shitara, Satoshi Ueha, Shigeyuki Shichino, Hiroyasu Aoki, Haru Ogiwara

J Immunother Cancer· July 2019

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