Publications by authors named "Hiroyuki Koide"

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In vivo delivery of antioxidant enzymes with multi-functionalized lipid nanoparticles for sepsis therapy.
Hiroyuki Koide, Shinya Hirata, Midori Watanabe, Hiroki Ochiai, Tatsuya Kobayashi

J Control Release· June 2025

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Process Optimization of Charge-Reversible Lipid Nanoparticles for Cytosolic Protein Delivery Using the Design-of-Experiment Approach.
Dai Oyama, Masako Okada, Furan Song, Chiori Nitta, Hiroyuki Koide

Biol Pharm Bull· May 2025

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Prediction and control of the particle size of polyethylene glycol-free lipid nanoparticles using a design of experiment.
Ryoko Saeki, Hiroyuki Koide, Furan Song, Sei Yonezawa, Masahiro Hashimoto

Biochem Biophys Res Commun· May 2025

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Development of a messenger RNA vaccine using pH-responsive dipeptide-conjugated lipids exhibiting reduced inflammatory properties.
Katsuki Matayoshi, Sayaka Takahashi, Sohei Ryu, Hiroyuki Koide, Sei Yonezawa

Int J Pharm· April 2025

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Influence of Size, Flexibility, Hydrophobicity, Surface Charge, and Surface Chemistry on the Biodistribution of Orally Administered Polymer Nanoparticles.
Go Yasuno, Hiroyuki Koide, Shinya Hirata, Takumi Okamoto, Midori Watanabe

Biol Pharm Bull· April 2025

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Enhanced oral insulin delivery with charge-reversible lipid nanoparticles.
Dai Oyama, Katsuki Matayoshi, Soya Kanetaka, Chiori Nitta, Hiroyuki Koide

Biochem Biophys Res Commun· March 2025

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Delivery of small interfering ribonucleic acid using lipid nanoparticles prepared with pH-responsive dipeptide-conjugated lipids.
Katsuki Matayoshi, Furan Song, Hiroyuki Koide, Sei Yonezawa, Chiori Nitta

Biochem Biophys Res Commun· October 2024

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Engineering Temperature-Responsive Polymer Nanoparticles that Load and Release Paclitaxel, a Low-Molecular-Weight Anticancer Drug.
Hiroyuki Koide, Kazuma Yamaguchi, Keijiro Sato, Maki Aoshima, Shoko Kanata

ACS Omega· January 2024

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Design of an Anti-HMGB1 Synthetic Antibody for Ischemic/Reperfusion Injury Therapy.
Hiroyuki Koide, Chiaki Kiyokawa, Anna Okishima, Kaito Saito, Keiichi Yoshimatsu

J Am Chem Soc· October 2023

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Treatment of PTEN-Null Breast Cancer by a Synthetic Lethal Approach Involving PARP1 Gene Silencing.
Tomohiro Asai, Masafumi Yokota, Hideki Isomura, Hiroyuki Koide, Naoyuki Sakurai

J Pharm Sci· July 2023

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Increasing the siRNA knockdown efficiency of lipid nanoparticles by morphological transformation with the use of dihydrosphingomyelin as a helper lipid.
Masahiro Hashimoto, Sei Yonezawa, Song Furan, Chiori Nitta, Noriyuki Maeda, Hiroyuki Koide

Biomater Sci· May 2023

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Cooling-induced, localized release of cytotoxic peptides from engineered polymer nanoparticles in living mice for cancer therapy.
Hiroyuki Koide, Kazuhiro Saito, Keiichi Yoshimatsu, Beverly Chou, Yu Hoshino

J Control Release· March 2023

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Easy preparation of a liposome-mediated protein delivery system by freeze-thawing a liposome-protein complex.
Hiroyuki Koide, Hiroki Ochiai, Hikaru Suzuki, Shinya Hirata, Midori Watanabe

J Mater Chem B· September 2022

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[Design of Synthetic Polymer Nanoparticles That Capture and Neutralize Target Molecules].
Hiroyuki Koide

Yakugaku Zasshi· December 2021

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Recent advances in siRNA delivery mediated by lipid-based nanoparticles.
Sei Yonezawa, Hiroyuki Koide, Tomohiro Asai

Adv Drug Deliv Rev· September 2021

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Influence of Purification Process on the Function of Synthetic Polymer Nanoparticles.
Go Yasuno, Hiroyuki Koide, Naoto Oku, Tomohiro Asai

Chem Pharm Bull (Tokyo)· September 2021

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Synthetic hydrogel nanoparticles for sepsis therapy.
Hiroyuki Koide, Anna Okishima, Yu Hoshino, Yuri Kamon, Keiichi Yoshimatsu

Nat Commun· September 2021

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Design of Functional Nanoparticles for Intractable Disease Therapy.
Hiroyuki Koide

Biol Pharm Bull· August 2021

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Design of abiotic polymer ligand-decorated lipid nanoparticles for effective neutralization of target toxins in the blood.
Hiroyuki Koide, Ikumi Yamauchi, Yu Hoshino, Go Yasuno, Takumi Okamoto

Biomater Sci· August 2021

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Design of synthetic polymer nanoparticles that inhibit glucose absorption from the intestine.
Hiroyuki Koide, Naoki Hayashi, Go Yasuno, Anna Okishima, Yu Hoshino

Biochem Biophys Res Commun· July 2021

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siRNA Vehicles for High Endosomal Escapability.
Hiroyuki Koide, Sei Yonezawa, Tomohiro Asai

Methods Mol Biol· June 2021

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Enhancement of target toxin neutralization effect in vivo by PEGylation of multifunctionalized lipid nanoparticles.
Hiroyuki Koide, Hikaru Suzuki, Hiroki Ochiai, Hiromichi Egami, Yoshitaka Hamashima

Biochem Biophys Res Commun· May 2021

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Charge-reversible lipid derivative: A novel type of pH-responsive lipid for nanoparticle-mediated siRNA delivery.
Yusuke Hirai, Ryoko Saeki, Furan Song, Hiroyuki Koide, Naofumi Fukata

Int J Pharm· July 2020

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Suppression of Cerebral Ischemia/Reperfusion Injury by Efficient Release of Encapsulated Ifenprodil From Liposomes Under Weakly Acidic pH Conditions.
Takashi Kikuchi, Tatsuya Fukuta, Yurika Agato, Yosuke Yanagida, Takayuki Ishii, Hiroyuki Koide

J Pharm Sci· December 2019

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Engineering the Binding Kinetics of Synthetic Polymer Nanoparticles for siRNA Delivery.
Hiroyuki Koide, Tatsuya Fukuta, Anna Okishim, Saki Ariizumi, Chiaki Kiyokawa

Biomacromolecules· October 2019

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