Publications by authors named "Hiroyuki Ohba"

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PET imaging of mitochondrial complex-I in the adenine-induced tubulointerstitial nephropathy mouse model using [F]BCPP-BF.
Kenneth Dahl, Peter Johnström, Miklós Toth, Vasco C Sousa, Charlotte Ericsson, Hiroyuki Ohba

EJNMMI Radiopharm Chem· October 2025

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[F]BCPP-BF-PET as an imaging tool for mitochondrial dysfunction in diabetic pancreatopathy and nephrotoxicity.
Yuki Tomonari, Masakatsu Kanazawa, Shingo Nishiyama, Hiroyuki Ohba, Hideo Tsukada

Nucl Med Biol· August 2025

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Cognitive effects of scopolamine on temporal preparation in male macaque monkeys.
Takahiro Tsuchiya, Dai Fukumoto, Takeharu Kakiuchi, Hiroyuki Ohba, Norihiro Harada

Behav Brain Res· July 2025

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Biodistribution of [F]BCPP-BF in humans: a first-in-human positron emission tomography study.
Kengo Sato, Tomoyasu Bunai, Akinori Oda, Hiroyuki Ohba, Yoshitaka Sano

Nucl Med Biol· June 2025

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[F]BCPP-EF positron emission tomography of rat ovaries for evaluation of mitochondrial function.
Yuki Tomonari, Hiroyuki Ohba, Hideo Tsukada

Nucl Med Biol· May 2025

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Animal PET scanner with a large field of view is suitable for high-throughput scanning of rodents.
Yuki Tomonari, Yuya Onishi, Fumio Hashimoto, Kibo Ote, Takashi Okamoto, Hiroyuki Ohba

Ann Nucl Med· July 2024

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Biodistribution assessment of cationic pullulan nanogel, a nasal vaccine delivery system, in mice and non-human primates.
Yoshikazu Yuki, Norihiro Harada, Shin-Ichi Sawada, Yohei Uchida, Rika Nakahashi-Ouchida, Hiroyuki Ohba

Vaccine· July 2023

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Brain p3-Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β-peptide.
Saori Hata, Haruka Saito, Takeharu Kakiuchi, Dai Fukumoto, Shigeyuki Yamamoto, Hiroyuki Ohba

EMBO Mol Med· May 2023

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Early distribution of F-labeled AAV9 vectors in the cerebrospinal fluid after intracerebroventricular or intracisternal magna infusion in non-human primates.
Shinichi Kumagai, Takeshi Nakajima, Kuniko Shimazaki, Takeharu Kakiuchi, Norihiro Harada, Hiroyuki Ohba

J Gene Med· January 2023

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Head-to-head comparison of (R)-[C]verapamil and [F]MC225 in non-human primates, tracers for measuring P-glycoprotein function.
Lara García-Varela, David Vállez García, Pablo Aguiar, Takeharu Kakiuchi, Hiroyuki Ohba

Eur J Nucl Med Mol Imaging· December 2021

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Anatomical-guided attention enhances unsupervised PET image denoising performance.
Yuya Onishi, Fumio Hashimoto, Kibo Ote, Hiroyuki Ohba, Ryosuke Ota

Med Image Anal· December 2021

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In vivo alterations of mitochondrial activity and amyloidosis in early-stage senescence-accelerated mice: a positron emission tomography study.
Satoru Yamagishi, Yurika Iga, Shunsuke Ikegaya, Takeharu Kakiuchi, Hiroyuki Ohba

J Neuroinflammation· December 2021

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Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity.
Rie Hosoi, Yuka Fujii, Ohba Hiroyuki, Miho Shukuri, Shingo Nishiyama

EJNMMI Res· October 2021

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4D deep image prior: dynamic PET image denoising using an unsupervised four-dimensional branch convolutional neural network.
Fumio Hashimoto, Hiroyuki Ohba, Kibo Ote, Akihiro Kakimoto, Hideo Tsukada

Phys Med Biol· January 2021

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Pharmacokinetic Modeling of ()-[C]verapamil to Measure the P-Glycoprotein Function in Nonhuman Primates.
Lara García-Varela, David Vállez García, Takeharu Kakiuchi, Hiroyuki Ohba, Shingo Nishiyama

Mol Pharm· January 2021

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Imaging mitochondrial complex I activation during a vibrotactile stimulation: A PET study using [F]BCPP-EF in the conscious monkey brain.
Jingwan Fang, Hiroyuki Ohba, Fumio Hashimoto, Hideo Tsukada, Feiyan Chen

J Cereb Blood Flow Metab· December 2020

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Synthesis and evaluation of N-isopropyl-p-[C]methylamphetamine as a novel cerebral blood flow tracer for positron emission tomography.
Jun Toyohara, Norihiro Harada, Takeharu Kakiuchi, Hiroyuki Ohba, Masakatsu Kanazawa

EJNMMI Res· October 2020

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Pharmacokinetic Modeling of [F]MC225 for Quantification of the P-Glycoprotein Function at the Blood-Brain Barrier in Non-Human Primates with PET.
Lara García-Varela, Wejdan M Arif, David Vállez García, Takeharu Kakiuchi, Hiroyuki Ohba

Mol Pharm· September 2020

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Positron emission tomography imaging of renal mitochondria is a powerful tool in the study of acute and progressive kidney disease models.
Satoshi Saeki, Hiroyuki Ohba, Yuko Ube, Kayoko Tanaka, Waka Haruyama

Kidney Int· July 2020

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Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study.
Satoru Yamagishi, Yurika Iga, Masato Nakamura, Chika Takizawa, Dai Fukumoto, Hiroyuki Ohba

J Neuroinflammation· November 2019

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Sensitive and early detection of mitochondrial dysfunction in the liver of NASH model mice by PET imaging with F-BCPP-BF.
Toshihiro Sakai, Hiroyuki Ohba, Shingo Nishiyama, Takeharu Kakiuchi, Osamu Inoue

EJNMMI Res· July 2018

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Effect of MPTP on Serotonergic Neuronal Systems and Mitochondrial Complex I Activity in the Living Brain: A PET Study on Conscious Rhesus Monkeys.
Masakatsu Kanazawa, Hiroyuki Ohba, Shingo Nishiyama, Takeharu Kakiuchi, Hideo Tsukada

J Nucl Med· July 2017

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In Vivo Evaluation of C-Preladenant for PET Imaging of Adenosine A Receptors in the Conscious Monkey.
Xiaoyun Zhou, Ronald Boellaard, Kiichi Ishiwata, Muneyuki Sakata, Rudi A J O Dierckx, Hiroyuki Ohba

J Nucl Med· May 2017

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Effect of Oxygen Affinity of Liposome-Encapsulated Hemoglobin on Cerebral Ischemia and Reperfusion as Detected by Positron Emission Tomography in Nonhuman Primates.
Akira T Kawaguchi, Mariko Yamano, Munetaka Haida, Hiroyuki Ohba, Takeharu Kakiuchi

Artif Organs· April 2017

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In vivo TSPO and cannabinoid receptor type 2 availability early in post-stroke neuroinflammation in rats: a positron emission tomography study.
Teruyo Hosoya, Dai Fukumoto, Takeharu Kakiuchi, Shingo Nishiyama, Shigeyuki Yamamoto, Hiroyuki Ohba

J Neuroinflammation· March 2017

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