Publications by authors named "Hiten D Madhani"

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Functional insight into cyclin-dependent kinase (CDK)7 via chemical inhibition of the priority fungal pathogen .
Pooja Sethiya, Desmarini Desmarini, Bethany Grace Bowring, Kyle Cesar, Michael J Boucher, Hiten D Madhani

mBio· December 2025

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CRISPR/Cas9-compatible plasmids enabling seven dominant genetic selection methods for the human fungal pathogen .
Michael J Boucher, Hiten D Madhani

Microbiol Spectr· November 2025

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Near 100% efficient homology-dependent genome engineering in the human fungal pathogen Cryptococcus neoformans.
Matthew J Nalley, Sanjita Banerjee, Manning Y Huang, Hiten D Madhani

G3 (Bethesda)· August 2025

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Phenotypic landscape of an invasive fungal pathogen reveals its unique biology.
Michael J Boucher, Sanjita Banerjee, Meenakshi B Joshi, Angela L Wei, Matthew J Nalley, Hiten D Madhani

Cell· July 2025

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An auxin-inducible degron system for conditional mutation in the fungal meningitis pathogen Cryptococcus neoformans.
Manning Y Huang, Matthew J Nalley, Patrick C Hecht, Hiten D Madhani

G3 (Bethesda)· June 2025

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Mechanisms of Inheritance of Chromatin States: From Yeast to Human.
Hiten D Madhani

Annu Rev Biophys· May 2025

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On-Resin Assembly of Macrocyclic Inhibitors of May1: A Pathway to Potent Antifungal Agents.
Robin Kryštůfek, Václav Verner, Pavel Šácha, Martin Hadzima, Filip Trajhan, Hiten D Madhani

J Med Chem· May 2025

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An auxin-inducible degron system for conditional mutation in the fungal meningitis pathogen .
Manning Y Huang, Matt J Nalley, Patrick Hecht, Hiten D Madhani

bioRxiv· November 2024

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Phenotypic landscape of a fungal meningitis pathogen reveals its unique biology.
Michael J Boucher, Sanjita Banerjee, Meenakshi B Joshi, Angela L Wei, Manning Y Huang, Hiten D Madhani

bioRxiv· October 2024

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Deep learning meets histones at the replication fork.
Hiten D Madhani

Cell· September 2024

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Understanding the dynamic design of the spliceosome.
Irene Beusch, Hiten D Madhani

Trends Biochem Sci· July 2024

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Convergent evolution of innate immune-modulating effectors in invasive fungal pathogens.
Michael J Boucher, Hiten D Madhani

Trends Microbiol· May 2024

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Intrinsic mesoscale properties of a Polycomb protein underpin heterochromatin fidelity.
Sujin Lee, Stephen Abini-Agbomson, Daniela S Perry, Allen Goodman, Beiduo Rao, Hiten D Madhani

Nat Struct Mol Biol· July 2023

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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system.
Marco De Giovanni, Eric V Dang, Kevin Y Chen, Jinping An, Hiten D Madhani

Immunity· July 2023

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Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles.
Irene Beusch, Beiduo Rao, Michael K Studer, Tetiana Luhovska, Viktorija Šukytė, Hiten D Madhani

Mol Cell· July 2023

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Deep tissue infection by an invasive human fungal pathogen requires lipid-based suppression of the IL-17 response.
Pauline Basso, Eric V Dang, Anatoly Urisman, Leah E Cowen, Hiten D Madhani

Cell Host Microbe· November 2022

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Secreted fungal virulence effector triggers allergic inflammation via TLR4.
Eric V Dang, Susan Lei, Atanas Radkov, Regan F Volk, Balyn W Zaro, Hiten D Madhani

Nature· August 2022

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Telomere transposon takeover in Cryptococcus.
Manning Y Huang, Hiten D Madhani

Nat Microbiol· August 2022

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Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance.
Juncheng Wang, Sandra Catania, Chongyuan Wang, M Jason de la Cruz, Beiduo Rao, Hiten D Madhani

Mol Cell· March 2022

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Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging.
Manning Y Huang, Meenakshi B Joshi, Michael J Boucher, Sujin Lee, Liza C Loza, Hiten D Madhani

Genetics· January 2022

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Coupling of spliceosome complexity to intron diversity.
Jade Sales-Lee, Daniela S Perry, Bradley A Bowser, Jolene K Diedrich, Beiduo Rao, Hiten D Madhani

Curr Biol· November 2021

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Model organism databases are in jeopardy.
Hugo J Bellen, E J A Hubbard, Ruth Lehmann, Hiten D Madhani, Lila Solnica-Krezel

Development· October 2021

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Re-emerging Aspartic Protease Targets: Examining Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Robin Kryštůfek, Pavel Šácha, Jana Starková, Jiří Brynda, Martin Hradilek, Hiten D Madhani

J Med Chem· May 2021

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Unbelievable but True: Epigenetics and Chromatin in Fungi.
Hiten D Madhani

Trends Genet· January 2021

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Coordinate genomic association of transcription factors controlled by an imported quorum sensing peptide in Cryptococcus neoformans.
Diana K Summers, Daniela S Perry, Beiduo Rao, Hiten D Madhani

PLoS Genet· September 2020

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