Publications by authors named "Hitoshi Doihara"

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The selective anaplastic lymphoma receptor tyrosine kinase inhibitor ASP3026 induces tumor regression and prolongs survival in non-small cell lung cancer model mice.
Masamichi Mori, Yoko Ueno, Satoshi Konagai, Hiroshi Fushiki, Itsuro Shimada, Hitoshi Doihara

Mol Cancer Ther· February 2014

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Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain.
Ryosuke Kojima, Katsura Nozawa, Hitoshi Doihara, Yoshihiro Keto, Hidetaka Kaku

Eur J Pharmacol· January 2014

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A novel glycine transporter-1 (GlyT1) inhibitor, ASP2535 (4-[3-isopropyl-5-(6-phenyl-3-pyridyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole), improves cognition in animal models of cognitive impairment in schizophrenia and Alzheimer's disease.
Katsuya Harada, Kazuhiro Nakato, Junko Yarimizu, Mayako Yamazaki, Masahiko Morita, Hitoshi Doihara

Eur J Pharmacol· June 2012

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Synthesis and biological evaluation of 3-biphenyl-4-yl-4-phenyl-4H-1,2,4-triazoles as novel glycine transporter 1 inhibitors.
Takashi Sugane, Takahiko Tobe, Wataru Hamaguchi, Itsuro Shimada, Kyoichi Maeno, Hitoshi Doihara

J Med Chem· January 2011

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Characterization of two models of drug-induced constipation in mice and evaluation of mustard oil in these models.
Ryosuke Kojima, Hitoshi Doihara, Katsura Nozawa, Eri Kawabata-Shoda, Toshihide Yokoyama

Pharmacology· January 2010

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QGP-1 cells release 5-HT via TRPA1 activation; a model of human enterochromaffin cells.
Hitoshi Doihara, Katsura Nozawa, Ryosuke Kojima, Eri Kawabata-Shoda, Toshihide Yokoyama

Mol Cell Biochem· November 2009

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TRPA1 agonists delay gastric emptying in rats through serotonergic pathways.
Hitoshi Doihara, Katsura Nozawa, Eri Kawabata-Shoda, Ryosuke Kojima, Toshihide Yokoyama

Naunyn Schmiedebergs Arch Pharmacol· October 2009

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Molecular cloning and characterization of dog TRPA1 and AITC stimulate the gastrointestinal motility through TRPA1 in conscious dogs.
Hitoshi Doihara, Katsura Nozawa, Eri Kawabata-Shoda, Ryosuke Kojima, Toshihide Yokoyama

Eur J Pharmacol· September 2009

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TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells.
Katsura Nozawa, Eri Kawabata-Shoda, Hitoshi Doihara, Ryosuke Kojima, Hidetsugu Okada

Proc Natl Acad Sci U S A· March 2009

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