Publications by authors named "Holger Winkels"

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Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease.
Dennis Mehrkens, Johannes Dohr, Felix Sebastian Nettersheim, Felix Ballmann, Jil Bastigkeit, Holger Winkels

Cardiovasc Res· December 2025

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An improved porcine model of infrarenal abdominal aortic aneurysm.
Marta Stei, Per Arkenberg, Theresa Uebing, Agnesa Mazrekaj, Joscha Mulorz, Holger Winkels

Sci Rep· December 2025

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High-Resolution Spatial Profiling Unveils Cellular Heterogeneity in Murine Atherosclerosis.
Jan Wrobel, Samuel Jung, Paul Kießling, Emilia Scheidereit, Christoph Kuppe, Holger Winkels

Thromb Haemost· November 2025

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Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome.
Ximena Hildebrandt, Önay Veli, Armel Hyoubi, Julia Zinngrebe, Ali T Abdallah, Holger Winkels

Sci Adv· September 2025

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Bacterial Infections Shape Cardiac Macrophages' Response to Ischemia.
Simon Geissen, Alexander Hof, Elvina Santhamma Philip, Elena Wagner, Charlotte Schreiber, Holger Winkels

Circ Res· August 2025

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Myeloperoxidase impacts vascular function by altering perivascular adipocytes' secretome and phenotype in obesity.
Alexander Hof, Max Landerer, Philipp Peitsmeyer, Ronja Herzog, Jens Alber, Holger Winkels

Cell Rep Med· May 2025

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Cancer Development and Progression in Patients with Heart Failure.
Katharina Seuthe, Felix Simon Ruben Picard, Holger Winkels, Roman Pfister

Curr Heart Fail Rep· December 2024

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Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition.
Anna C Beielstein, Elena Izquierdo, Stuart Blakemore, Nadine Nickel, Michael Michalik, Holger Winkels

Cell Rep Med· December 2024

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Cross-species single-cell RNA sequencing reveals divergent phenotypes and activation states of adaptive immunity in human carotid and experimental murine atherosclerosis.
Hauke Horstmann, Nathaly Anto Michel, Xia Sheng, Sophie Hansen, Alexandra Lindau, Holger Winkels

Cardiovasc Res· November 2024

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Hematopoietic PI3Kδ deficiency aggravates murine atherosclerosis through impairment of Tregs.
Mario Zierden, Eva Maria Berghausen, Leoni Gnatzy-Feik, Christopher Millarg, Felix Simon Ruben Picard, Holger Winkels

JCI Insight· November 2024

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Decoding Macrophage Heterogeneity to Unravel Vascular Inflammation as a Path to Precision Medicine.
Sarvesh Chelvanambi, Julius L Decano, Holger Winkels, Chiara Giannarelli, Masanori Aikawa

Arterioscler Thromb Vasc Biol· November 2024

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Physiologists as medical scientists: An early warning from the German academic system.
Katrin Streckfuss-Bömeke, Nicolle Kränkel, Christoph Maack, Renate B Schnabel, Laura C Zelarayán, Holger Winkels

Physiol Rep· November 2024

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Inhibition of myeloperoxidase to treat left ventricular dysfunction in non-ischaemic cardiomyopathy.
Simon Geissen, Simon Braumann, Joana Adler, Felix Sebastian Nettersheim, Dennis Mehrkens, Holger Winkels

Eur J Heart Fail· October 2024

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Myeloperoxidase induces monocyte migration and activation after acute myocardial infarction.
Vera B M Peters, Friederike Matheis, Immanuel Erdmann, Harshal N Nemade, David Muders, Holger Winkels

Front Immunol· May 2024

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Acute and short-term fluctuations in gravity are associated with changes in circulatory plasma protein levels.
Alexander Lang, Stephan Binneboessel, Fabian Nienhaus, Raphael Romano Bruno, Georg Wolff, Holger Winkels

NPJ Microgravity· March 2024

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Macrophage mediators and mechanisms in cardiovascular disease.
Patrik Schelemei, Elena Wagner, Felix Simon Ruben Picard, Holger Winkels

FASEB J· February 2024

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Editorial: Role of innate and adaptive immune cells in the metabolic syndrome.
Payel Roy, Holger Winkels, Marco Orecchioni, Estefania Quesada-Masachs, Thomas Riffelmacher

Front Cell Dev Biol· February 2024

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Application and challenges of TCR and BCR sequencing to investigate T- and B-cell clonality in elastase-induced experimental murine abdominal aortic aneurysm.
Christin Elster, Miriam Ommer-Bläsius, Alexander Lang, Tanja Vajen, Susanne Pfeiler, Holger Winkels

Front Cardiovasc Med· November 2023

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Identification of human exT cells as CD16CD56 cytotoxic CD4 T cells.
Antoine Freuchet, Payel Roy, Sujit Silas Armstrong, Mohammad Oliaeimotlagh, Sunil Kumar, Holger Winkels

Nat Immunol· October 2023

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Vascular Ultrasound for In Vivo Assessment of Arterial Pathologies in a Murine Model of Atherosclerosis and Aortic Aneurysm.
Alexander Hof, Henning Guthoff, Maysam Ahdab, Max Landerer, Jasper Schäkel, Holger Winkels

Int J Mol Sci· October 2023

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Rational and design of the REMOTE trial: An exploratory, pilot study to analyze REtinal MicrOcirculaTion in wEightlessness.
Stephan Binneboessel, Maryna Masyuk, Kerstin Piayda, Raphael Romano Bruno, Bernhard Wernly, Holger Winkels

Clin Hemorheol Microcirc· September 2023

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Myeloperoxidase is a critical mediator of anthracycline-induced cardiomyopathy.
Felix Sebastian Nettersheim, Johannes David Schlüter, Wiebke Kreuzberg, Dennis Mehrkens, Simon Grimm, Holger Winkels

Basic Res Cardiol· September 2023

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Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells.
Felix Sebastian Nettersheim, Yanal Ghosheh, Holger Winkels, Kouji Kobiyama, Christopher Durant

Front Cardiovasc Med· January 2023

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Editorial: Immune and autoimmune mechanisms in cardiovascular disease.
Holger Winkels, Norbert Gerdes, Florian Kahles, Partha Dutta, Chiara Giannarelli

Front Cardiovasc Med· January 2023

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Protective Effects of Therapeutic Neutrophil Depletion and Myeloperoxidase Inhibition on Left Ventricular Function and Remodeling in Myocardial Infarction.
Henning Guthoff, Alexander Hof, Anna Klinke, Martina Maaß, Jürgen Konradi, Holger Winkels

Antioxidants (Basel)· December 2022

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