Publications by authors named "Hong-Jen Lee"

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MIG-6 is essential for promoting glucose metabolic reprogramming and tumor growth in triple-negative breast cancer.
Jiabei He, Chien-Feng Li, Hong-Jen Lee, Dong-Hui Shin, Yi-Jye Chern

EMBO Rep· May 2021

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HectH9 hijacks glucose metabolism to fuel tumor growth.
Hong-Jen Lee, Jiabei He, Chia-Hsin Chan

Mol Cell Oncol· July 2019

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Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion.
Hong-Jen Lee, Chien-Feng Li, Diane Ruan, Jiabei He, Emily D Montal

Nat Commun· June 2019

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Inhibition of USP2 eliminates cancer stem cells and enhances TNBC responsiveness to chemotherapy.
Jiabei He, Hong-Jen Lee, Suchandrima Saha, Diane Ruan, Hua Guo

Cell Death Dis· March 2019

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Two-faced activity of RNF8: What "twists" it from a genome guardian to a cancer facilitator?
Hong-Jen Lee, Diane Ruan, Jiabei He, Chia-Hsin Chan

Mol Cell Oncol· October 2016

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The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation.
Hong-Jen Lee, Chien-Feng Li, Diane Ruan, Scott Powers, Patricia A Thompson

Mol Cell· September 2016

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PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response.
Hsin-Wei Liao, Jung-Mao Hsu, Weiya Xia, Hung-Ling Wang, Ying-Nai Wang, Hong-Jen Lee, Heng-Huan Lee

J Clin Invest· December 2015

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Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response.
Hong-Jen Lee, Li Lan, Guang Peng, Wei-Chao Chang, Ming-Chuan Hsu

Cell Res· February 2015

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EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4.
Ruey-Hwang Chou, Ying-Nai Wang, Yi-Hsien Hsieh, Long-Yuan Li, Weiya Xia, Hong-Jen Lee

Dev Cell· July 2014

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mMAPS: a flow-proteometric technique to analyze protein-protein interactions in individual signaling complexes.
Chao-Kai Chou, Heng-Huan Lee, Pei-Hsiang Tsou, Chun-Te Chen, Jung-Mao Hsu, Hong-Jen Lee, Jin-Fong Lee

Sci Signal· March 2014

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Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776.
Yung-Luen Yu, Ruey-Hwang Chou, Chia-Han Wu, Ying-Nai Wang, Wei-Jung Chang, Hong-Jen Lee

J Biol Chem· September 2012

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Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.
Ying-Nai Wang, Heng-Huan Lee, Hong-Jen Lee, Yi Du, Hirohito Yamaguchi

J Biol Chem· May 2012

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IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression.
Mo Liu, Dung-Fang Lee, Chun-Te Chen, Chia-Jui Yen, Long-Yuan Li, Hong-Jen Lee

Mol Cell· January 2012

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Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase.
Chun-Te Chen, Hirohito Yamaguchi, Hong-Jen Lee, Yi Du, Heng-Huan Lee

Mol Cancer Ther· August 2011

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Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation.
Jung-Mao Hsu, Chun-Te Chen, Chao-Kai Chou, Hsu-Ping Kuo, Long-Yuan Li, Hong-Jen Lee

Nat Cell Biol· February 2011

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The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus.
Ying-Nai Wang, Hirohito Yamaguchi, Longfei Huo, Yi Du, Hong-Jen Lee, Heng-Huan Lee

J Biol Chem· December 2010

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COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport.
Ying-Nai Wang, Hongmei Wang, Hirohito Yamaguchi, Hong-Jen Lee, Heng-Huan Lee

Biochem Biophys Res Commun· September 2010

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ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.
Hsu-Ping Kuo, Dung-Fang Lee, Chun-Te Chen, Mo Liu, Chao-Kai Chou, Hong-Jen Lee

Sci Signal· February 2010

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Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.
Hong-Jen Lee, Yuan-Shou Chen, Chi-Yuan Chou, Chia-Hui Chien, Chun-Hung Lin

J Biol Chem· December 2006

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Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists.
Neeraj Mahindroo, Yi-Hui Peng, Chia-Hui Lin, Uan-Kang Tan, Ekambaranellore Prakash, Hong-Jen Lee

J Med Chem· October 2006

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Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors.
Ting-Yueh Tsai, Mohane Selvaraj Coumar, Tsu Hsu, Hsing-Pang Hsieh, Chia-Hui Chien, Hong-Jen Lee

Bioorg Med Chem Lett· June 2006

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Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition.
Yu-San Han, Gu-Gang Chang, Chiun-Gung Juo, Hong-Jen Lee, Shiou-Hwei Yeh

Biochemistry· August 2005

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Large-scale sequencing analysis of the full-length cDNA library of human hepatocellular carcinoma.
Chia-Chu Tsai, Yi-Da Chung, Hong-Jen Lee, Wen-Hsin Chang, Yutaka Suzuku

J Biomed Sci· July 2004

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