Publications by authors named "Hongkai Bi"

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Switching the strict substrate specificities of the β-ketoacyl-acyl carrier protein synthases, FabH and BioZ.
Xudong Hang, Lin Zhang, Yanqiang Huang, Yuanyuan Hu, Qi Zeng, Hongkai Bi

Proc Natl Acad Sci U S A· November 2025

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Chemical constituents of the aerial parts of (L.) DC (Rubiaceae).
Xinyi Wei, Yingrun Ma, Mingming Xu, Ding Heng, Monday M Onakpa, Hongkai Bi

Nat Prod Res· August 2025

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Discovery of 1,3,4-Thiadiazole Sulfonamide-Based Potent Inhibitors against the Unsaturated Fatty Acid Synthase FabX of .
Xiaoxue Ruan, Lin Zhang, Linlin Dong, Yue Wang, Liping Zeng, Hongkai Bi

J Med Chem· August 2025

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2-oxoglutarate:acceptor oxidoreductase-catalyzed redox cycling effectively targets coccoid forms of Helicobacter pylori.
Xudong Hang, Weiqi Lan, Huang Yanqiang, Hongming Huang, Mingjing Zhang, Shuzhuang Bi, Hongkai Bi

Nat Commun· July 2025

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Antagonist Targeting the Species-Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti-H. pylori Infection.
Lin Zhang, Xiaoxue Ruan, Xudong Hang, Ding Heng, Chang Cai, Hongkai Bi

Adv Sci (Weinh)· May 2025

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siRNA-AGO2 complex inhibits bacterial gene translation: A promising therapeutic strategy for superbug infection.
Chen Wang, Wangjian Sheng, Yu Zhou, Xudong Hang, Jiayi Zhao, Hongkai Bi

Cell Rep Med· March 2025

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Novel antibody-antibiotic conjugate using KRM-1657 as payload eliminates intracellular MRSA in vitro and in vivo.
Shiyong Fan, Yuefan Bai, Qilong Li, Lianqi Liu, Yanming Wang, Hongkai Bi

Bioorg Chem· September 2024

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Correction for Huang et al., " and Activities of Zinc Linolenate, a Selective Antibacterial Agent against ".
Yanqiang Huang, Xudong Hang, Xueqing Jiang, Liping Zeng, Jia Jia, Hongkai Bi

Antimicrob Agents Chemother· August 2024

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Correction for Chen et al., "Repurposing a human acetyl-CoA carboxylase inhibitor firsocostat to treat fungal candidiasis alone and in combination".
Tianyu Chen, Jing Yao, Keao Quan, Jingchen Xu, Xudong Hang, Hongkai Bi

Antimicrob Agents Chemother· June 2024

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Loureirin A is a narrow-spectrum antimicrobial agent against .
Qian Tong, Chengqiang Yin, Xudong Hang, Yuefan Bai, Chongwen Zhang, Hongkai Bi

Antimicrob Agents Chemother· June 2024

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Evaluating the potency of zoliflodacin against Helicobacter pylori: In vitro activity and conserved GyrB target.
Jing Liu, Jia Jia, Ting Shi, Yuefan Bai, Yanqiang Huang, Hongkai Bi

Helicobacter· April 2024

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Design, Synthesis, and Biological Evaluation of 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine (AF-353) Derivatives as Novel DHFR Inhibitors against .
Zongkai Huang, Xupeng Gou, Xudong Hang, Ting Shi, Jiaxing Yang, Hongkai Bi

J Med Chem· March 2024

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Repurposing a human acetyl-CoA carboxylase inhibitor firsocostat to treat fungal candidiasis alone and in combination.
Tianyu Chen, Jing Yao, Keao Quan, Jingchen Xu, Xudong Hang, Hongkai Bi

Antimicrob Agents Chemother· January 2024

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Novel citrinin derivatives from fungus Penicillium sp. TW131-64 and their antimicrobial activities.
Changrong Lai, Danmei Tian, Mingxin Zheng, Binglei Li, Jia Jia, Bin Wu, Hongkai Bi

Appl Microbiol Biotechnol· November 2023

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Killing of persisters by a multitarget natural product chrysomycin A.
Jia Jia, Mingxin Zheng, Chongwen Zhang, Binglei Li, Cai Lu, Hongkai Bi

Sci Adv· August 2023

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Alternarialone A, a new curvularin-type metabolite from the mangrove-derived fungus .
Rui-Yun Huo, Jin-Xin Zhang, Jia Jia, Hong-Kai Bi, Ling Liu

J Asian Nat Prod Res· June 2023

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Polyketides with potential bioactivities from the mangrove-derived fungus sp. WHUF0362.
Huawei Lv, Haibo Su, Yaxin Xue, Jia Jia, Hongkai Bi

Mar Life Sci Technol· May 2023

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Aculeaxanthones A-E, new xanthones from the marine-derived fungus WHUF0198.
Jun Wu, Hua Shui, Mengke Zhang, Yida Zeng, Mingxin Zheng, Hongkai Bi

Front Microbiol· February 2023

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New Polyketides from a Hydrothermal Vent Sediment Fungus sp. JWM29-10-1 and Their Antimicrobial Effects.
Changrong Lai, Jiayi Chen, Jing Liu, Danmei Tian, Donghe Lan, Bin Wu, Hongkai Bi

Mar Drugs· November 2022

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Two New Austocystin Analogs from the Marine-Derived Fungus Aspergillus sp. WHUF05236.
Huawei Lv, Jinkun Zhang, Yaxin Xue, Songwei Li, Xiaoyu Sun, Hongkai Bi

Chem Biodivers· June 2022

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A phosphopantetheinyl transferase gene restricted to Porphyromonas.
Liping Zeng, Guowei Zhong, Yan Huang, Jia Jia, Hongkai Bi

Res Microbiol· May 2022

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Quinone Derivatives as Promising Anti- Agents from Aerial Parts of .
Mingming Xu, Junfei Zhou, Ding Heng, Xiaorong Su, Monday M Onakpa, Hongkai Bi

J Nat Prod· April 2022

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KCNN4-mediated Ca/MET/AKT axis is promising for targeted therapy of pancreatic ductal adenocarcinoma.
Xiao Mo, Cheng-Fei Zhang, Ping Xu, Min Ding, Zhi-Jie Ma, Hong-Kai Bi

Acta Pharmacol Sin· March 2022

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New diketopiperazine alkaloid and polyketides from marine-derived fungus Penicillium sp. TW58-16 with antibacterial activity against Helicobacter pylori.
Danmei Tian, Xiaoshuang Gou, Jia Jia, Jihua Wei, Mingxin Zheng, Hongkai Bi, Bin Wu

Fitoterapia· January 2022

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Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis.
Jiashen Zhou, Lin Zhang, Liping Zeng, Lu Yu, Yuanyuan Duan, Hongkai Bi

Nat Commun· November 2021

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