Publications by authors named "Honnappa Jayakumar"

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Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): a highly selective 5-hydroxytryptamine2A receptor inverse agonist for the treatment of arterial thrombosis.
Yifeng Xiong, Bradley R Teegarden, Jin-Sun Karoline Choi, Sonja Strah-Pleynet, Marc Decaire, Honnappa Jayakumar

J Med Chem· June 2010

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Discovery of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (nelotanserin) and related 5-hydroxytryptamine2A inverse agonists for the treatment of insomnia.
Bradley R Teegarden, Hongmei Li, Honnappa Jayakumar, Sonja Strah-Pleynet, Peter I Dosa

J Med Chem· March 2010

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Solubilized phenyl-pyrazole ureas as potent, selective 5-HT(2A) inverse-agonists and their application as antiplatelet agents.
Peter I Dosa, Sonja Strah-Pleynet, Honnappa Jayakumar, Martin Casper, Marc Decaire

Bioorg Med Chem Lett· September 2009

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Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist.
Ila Sircar, Kristjan S Gudmundsson, Richard Martin, Jimmy Liang, Sumihiro Nomura, Honnappa Jayakumar

Bioorg Med Chem· June 2002

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