Publications by authors named "Hope Burks"

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Crosstalk in Skin: Loss of Desmoglein 1 in Keratinocytes Inhibits BRAF-Induced Cellular Senescence in Human Melanocytes.
Xin Tong, Hope E Burks, Ziyou Ren, Jennifer L Koetsier, Quinn R Roth-Carter

J Invest Dermatol· July 2025

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Melanoma cells repress Desmoglein 1 in keratinocytes to promote tumor cell migration.
Hope E Burks, Jenny L Pokorny, Jennifer L Koetsier, Quinn R Roth-Carter, Christopher R Arnette

J Cell Biol· November 2023

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Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis.
Quinn R Roth-Carter, Hope E Burks, Ziyou Ren, Jennifer L Koetsier, Lam C Tsoi

JCI Insight· August 2023

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Crosstalk in skin: Loss of desmoglein 1 in keratinocytes inhibits BRAF-induced cellular senescence in human melanocytes.
Xin Tong, Hope E Burks, Ziyou Ren, Jennifer L Koetsier, Quinn R Roth-Carter

bioRxiv· February 2023

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Liver Kinase B1 Regulates Remodeling of the Tumor Microenvironment in Triple-Negative Breast Cancer.
Connor T King, Margarite D Matossian, Jonathan J Savoie, Khoa Nguyen, Maryl K Wright, Hope E Burks

Front Mol Biosci· June 2022

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Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.
Lisa M Godsel, Quinn R Roth-Carter, Jennifer L Koetsier, Lam C Tsoi, Amber L Huffine, Hope E Burks

J Clin Invest· February 2022

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Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple-negative breast cancer through FRA-1 regulation.
Van T Hoang, Margarite D Matossian, Jacqueline La, Kristine Hoang, Deniz A Ucar, Hope E Burks

J Cell Biochem· August 2021

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NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells.
Margarite D Matossian, Steven Elliott, T Van Hoang, Hope E Burks, Maryl K Wright

Breast Cancer Res Treat· August 2021

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ZEB2 regulates endocrine therapy sensitivity and metastasis in luminal a breast cancer cells through a non-canonical mechanism.
Hope E Burks, Margarite D Matossian, Lyndsay Vanhoy Rhodes, Theresa Phamduy, Steven Elliott

Breast Cancer Res Treat· August 2021

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Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pathways that promote a mesenchymal and fulvestrant-resistant phenotype in breast cancer cells.
Margarite D Matossian, Steven Elliott, Lyndsay V Rhodes, Elizabeth C Martin, Van T Hoang, Hope E Burks

Oncol Lett· May 2021

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Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer.
Margarite D Matossian, Van T Hoang, Hope E Burks, Jacqueline La, Steven Elliott

Oncoscience· May 2021

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Correction: Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor.
Tiffany C Chang, Margarite D Matossian, Steven Elliott, Hope E Burks, Rachel A Sabol

PLoS One· April 2021

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Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor.
Tiffany C Chang, Margarite D Matossian, Steven Elliott, Hope E Burks, Rachel A Sabol

PLoS One· November 2020

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A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways.
Margarite D Matossian, Hope E Burks, Steven Elliott, Van T Hoang, William J Zuercher

Anticancer Drugs· September 2020

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ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer.
Van T Hoang, Margarite D Matossian, Deniz A Ucar, Steven Elliott, Jacqueline La, Hope E Burks

Front Oncol· August 2020

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Keratinocyte cadherin desmoglein 1 controls melanocyte behavior through paracrine signaling.
Christopher R Arnette, Quinn R Roth-Carter, Jennifer L Koetsier, Joshua A Broussard, Hope E Burks

Pigment Cell Melanoma Res· March 2020

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Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner.
Alejandra Valenzuela-Iglesias, Hope E Burks, Christopher R Arnette, Amulya Yalamanchili, Oxana Nekrasova

Mol Cancer Res· May 2019

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Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models.
Rachel A Sabol, Annie C Bowles, Alex Côté, Rachel Wise, Benjamen O'Donnell, Hope E Burks

Breast Cancer Res· May 2019

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Drug resistance profiling of a new triple negative breast cancer patient-derived xenograft model.
Margarite D Matossian, Hope E Burks, Steven Elliott, Van T Hoang, Annie C Bowles

BMC Cancer· March 2019

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A novel patient-derived xenograft model for claudin-low triple-negative breast cancer.
Margarite D Matossian, Hope E Burks, Annie C Bowles, Steven Elliott, Van T Hoang

Breast Cancer Res Treat· June 2018

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Panobinostat suppresses the mesenchymal phenotype in a novel claudin-low triple negative patient-derived breast cancer model.
Margarite D Matossian, Hope E Burks, Steven Elliott, Van T Hoang, Annie C Bowles

Oncoscience· March 2018

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Endocrine disruptors and the tumor microenvironment: A new paradigm in breast cancer biology.
Hope Burks, Nicholas Pashos, Elizabeth Martin, John Mclachlan, Bruce Bunnell

Mol Cell Endocrinol· December 2017

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Dual Src Kinase/Pretubulin Inhibitor KX-01, Sensitizes ERα-negative Breast Cancers to Tamoxifen through ERα Reexpression.
Muralidharan Anbalagan, Mei Sheng, Brian Fleischer, Yifang Zhang, Yuanjun Gao, Hope E Burks

Mol Cancer Res· November 2017

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Novel application of the published kinase inhibitor set to identify therapeutic targets and pathways in triple negative breast cancer subtypes.
Margarite D Matossian, Steven Elliott, Van T Hoang, Hope E Burks, Theresa B Phamduy

PLoS One· September 2017

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Aging is associated with impaired angiogenesis, but normal microvascular network structure, in the rat mesentery.
Richard S Sweat, David C Sloas, Scott A Stewart, Malwina Czarny-Ratajczak, Melody Baddoo, Hope E Burks

Am J Physiol Heart Circ Physiol· February 2017

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